ID A0A2T0M672_9ACTN Unreviewed; 971 AA.
AC A0A2T0M672;
DT 18-JUL-2018, integrated into UniProtKB/TrEMBL.
DT 18-JUL-2018, sequence version 1.
DT 24-JAN-2024, entry version 20.
DE SubName: Full=DNA-binding SARP family transcriptional activator {ECO:0000313|EMBL:PRX52885.1};
GN ORFNames=B0I32_1293 {ECO:0000313|EMBL:PRX52885.1};
OS Nonomuraea fuscirosea.
OC Bacteria; Actinomycetota; Actinomycetes; Streptosporangiales;
OC Streptosporangiaceae; Nonomuraea.
OX NCBI_TaxID=1291556 {ECO:0000313|EMBL:PRX52885.1, ECO:0000313|Proteomes:UP000238312};
RN [1] {ECO:0000313|EMBL:PRX52885.1, ECO:0000313|Proteomes:UP000238312}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CGMCC 4.7104 {ECO:0000313|EMBL:PRX52885.1,
RC ECO:0000313|Proteomes:UP000238312};
RA Whitman W.;
RT "Genomic Encyclopedia of Type Strains, Phase III (KMG-III): the genomes of
RT soil and plant-associated and newly described type strains.";
RL Submitted (MAR-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the AfsR/DnrI/RedD regulatory family.
CC {ECO:0000256|ARBA:ARBA00005820}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PRX52885.1}.
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DR EMBL; PVNG01000029; PRX52885.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2T0M672; -.
DR Proteomes; UP000238312; Unassembled WGS sequence.
DR GO; GO:0043531; F:ADP binding; IEA:InterPro.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0000160; P:phosphorelay signal transduction system; IEA:InterPro.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR CDD; cd15831; BTAD; 1.
DR Gene3D; 1.10.8.430; Helical domain of apoptotic protease-activating factors; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR Gene3D; 1.25.40.10; Tetratricopeptide repeat domain; 2.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR042197; Apaf_helical.
DR InterPro; IPR005158; BTAD.
DR InterPro; IPR002182; NB-ARC.
DR InterPro; IPR001867; OmpR/PhoB-type_DNA-bd.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR016032; Sig_transdc_resp-reg_C-effctor.
DR InterPro; IPR011990; TPR-like_helical_dom_sf.
DR InterPro; IPR019734; TPR_repeat.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR PANTHER; PTHR47691:SF3; HTH-TYPE TRANSCRIPTIONAL REGULATOR RV0890C-RELATED; 1.
DR PANTHER; PTHR47691; REGULATOR-RELATED; 1.
DR Pfam; PF03704; BTAD; 1.
DR Pfam; PF00931; NB-ARC; 1.
DR Pfam; PF13374; TPR_10; 1.
DR Pfam; PF13424; TPR_12; 1.
DR Pfam; PF00486; Trans_reg_C; 1.
DR PRINTS; PR00364; DISEASERSIST.
DR SMART; SM01043; BTAD; 1.
DR SMART; SM00028; TPR; 5.
DR SMART; SM00862; Trans_reg_C; 1.
DR SUPFAM; SSF46894; C-terminal effector domain of the bipartite response regulators; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF48452; TPR-like; 3.
PE 3: Inferred from homology;
KW DNA-binding {ECO:0000313|EMBL:PRX52885.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000238312}.
FT DOMAIN 17..93
FT /note="OmpR/PhoB-type"
FT /evidence="ECO:0000259|SMART:SM00862"
FT DOMAIN 100..244
FT /note="Bacterial transcriptional activator"
FT /evidence="ECO:0000259|SMART:SM01043"
FT REGION 289..334
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 971 AA; 104797 MW; F2219C9FA214BF52 CRC64;
MRLEIRCLGP WEVEADGEPV QIAGARRVGV LARLALAAGR SVAAERLLSD VWESSSAATA
GKQVHIVISK LREAFAAHGG AELIETVPGG YRLAMEPDHV DAHAFTSLAG RARAAHAGGS
LATADALFRG ALGLWRGTAL AEVDATWARI ESDRLEAERL AVLEDHADLR LSAGEHRALA
GELAAYVSTH PLRERPAAQL MLALYRDGRA PEALEVYQRL RRIMVEELGV EPGTEIRELQ
QAVLVKDPEL DLPPEHRAEP GRPVAPAELP AGTQAFTARA AEIERLRADL TGDSGTEQPG
SGPTGGFKAE PPGTALTGAT RGEPPRTGAA GGGAVTVISG PGGIGKSALA VHVAHTVARR
FTDGVIYVDL HGSTAGLTPL TPVEALRHLL RSLGLDGTAV PVDAEEAAAR YRSLTAAGHL
LVILDNARDA RQVRSLLPAG PGCRVLVTSR DPLVTLDNAR HLRLGRLDDT EAVALLARVA
GAGRVEAEPE AALEIARLCG GFPLALRIMG ARLAARPDWS PADLAVRLAD ATRRLDLLEY
ADLAVRASIA VSHEQLREEP GRRDAARLLA LLGLVDLPTH TLATTAALTD WTERRAETAL
EHLTDARLLE PAESGRYRMH DLVRLYAREQ QVPDDDRAGA AGRVLDHYLA TAQQACTLLF
GGGVVNGMVP TERPGEELTT LADANDWVRR ERDNLLATAR QAARDAHSPA ANLANAIIWL
FERRGWFPEL IEVTEEALRL TEEEQDWTAR AYLLQGLGGI HQQLGRFRTG VTHLEEGLAC
WDRAGQPDNK AGILNDLGVT YTVMGRYDDA HAALEAALAI IERTKRKDRE SYVRNNRVHV
FYRQGRHEEA VSEARHALAL TEESGDTGDL GIANDSLADA YRACGMLSDA VGKYRRAIEL
QRTAGFAVGT AVSCWWLGHT LYDLGRHEEA RESWQESLEI LREARLLTPA EVAGYLAQPI
PDTPVPIRNQ L
//
