ID A0A2T0MCW4_9FLAO Unreviewed; 969 AA.
AC A0A2T0MCW4;
DT 18-JUL-2018, integrated into UniProtKB/TrEMBL.
DT 18-JUL-2018, sequence version 1.
DT 24-JAN-2024, entry version 13.
DE RecName: Full=beta-N-acetylhexosaminidase {ECO:0000256|ARBA:ARBA00012663};
DE EC=3.2.1.52 {ECO:0000256|ARBA:ARBA00012663};
GN ORFNames=CLV81_3722 {ECO:0000313|EMBL:PRX55313.1};
OS Allomuricauda pacifica.
OC Bacteria; Bacteroidota; Flavobacteriia; Flavobacteriales;
OC Flavobacteriaceae; Allomuricauda.
OX NCBI_TaxID=1080225 {ECO:0000313|EMBL:PRX55313.1, ECO:0000313|Proteomes:UP000237640};
RN [1] {ECO:0000313|EMBL:PRX55313.1, ECO:0000313|Proteomes:UP000237640}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 25027 {ECO:0000313|EMBL:PRX55313.1,
RC ECO:0000313|Proteomes:UP000237640};
RA Goeker M.;
RT "Genomic Encyclopedia of Archaeal and Bacterial Type Strains, Phase II
RT (KMG-II): from individual species to whole genera.";
RL Submitted (MAR-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=Hydrolysis of terminal non-reducing N-acetyl-D-hexosamine
CC residues in N-acetyl-beta-D-hexosaminides.; EC=3.2.1.52;
CC Evidence={ECO:0000256|ARBA:ARBA00001231};
CC -!- SIMILARITY: Belongs to the glycosyl hydrolase 3 family.
CC {ECO:0000256|ARBA:ARBA00005336}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PRX55313.1}.
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DR EMBL; PVYX01000002; PRX55313.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2T0MCW4; -.
DR OrthoDB; 9805821at2; -.
DR Proteomes; UP000237640; Unassembled WGS sequence.
DR GO; GO:0004553; F:hydrolase activity, hydrolyzing O-glycosyl compounds; IEA:InterPro.
DR GO; GO:0005975; P:carbohydrate metabolic process; IEA:InterPro.
DR Gene3D; 3.40.710.10; DD-peptidase/beta-lactamase superfamily; 1.
DR Gene3D; 3.40.50.1700; Glycoside hydrolase family 3 C-terminal domain; 1.
DR Gene3D; 3.20.20.300; Glycoside hydrolase, family 3, N-terminal domain; 1.
DR InterPro; IPR001466; Beta-lactam-related.
DR InterPro; IPR012338; Beta-lactam/transpept-like.
DR InterPro; IPR036881; Glyco_hydro_3_C_sf.
DR InterPro; IPR001764; Glyco_hydro_3_N.
DR InterPro; IPR036962; Glyco_hydro_3_N_sf.
DR InterPro; IPR017853; Glycoside_hydrolase_SF.
DR PANTHER; PTHR30480:SF13; BETA-HEXOSAMINIDASE; 1.
DR PANTHER; PTHR30480; BETA-HEXOSAMINIDASE-RELATED; 1.
DR Pfam; PF00144; Beta-lactamase; 1.
DR Pfam; PF00933; Glyco_hydro_3; 1.
DR PRINTS; PR00133; GLHYDRLASE3.
DR SUPFAM; SSF51445; (Trans)glycosidases; 1.
DR SUPFAM; SSF56601; beta-lactamase/transpeptidase-like; 1.
PE 3: Inferred from homology;
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000313|EMBL:PRX55313.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000237640};
KW Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..19
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 20..969
FT /note="beta-N-acetylhexosaminidase"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5015641639"
FT DOMAIN 43..358
FT /note="Glycoside hydrolase family 3 N-terminal"
FT /evidence="ECO:0000259|Pfam:PF00933"
FT DOMAIN 590..946
FT /note="Beta-lactamase-related"
FT /evidence="ECO:0000259|Pfam:PF00144"
SQ SEQUENCE 969 AA; 108860 MW; 44E312A20C171BE3 CRC64;
MRINVYFPLL LLFFLGAKAQ NPLVAKDTLA QMEWVDNTYN NLTLEEKIGQ LFMVSIGSNK
SVESTNRIQS LIENQHVGGV IFLKGGPVQQ VRLTNEFQSK SKIPLMIGMD AEWGLAMRLD
STYAFPWNMT LGAIQDDKIV EKVGFQIGKH AKRMGVHINF APDIDVNNNP RNPIIGNRSF
GESPENVANK GLAIMKGMQK AGILACGKHF PGHGDTDVDS HKALPIIDAD RQRLDSIELY
PFKYLIKNGL SSVMVAHLDV PCLESRDGHP SSLSKSIISD LLIKELGFEG LVFTDALNMK
AVSQFANEGE VELESFLAGT DVLLMPQNPM ESIKRFIDAY NTGRISEYRL SLSVKKILMA
KYKAGLHTYV PVAEENLLNE LNGVENDIIY EESIEKALTV AKNNFSLLPI KNLENKRIAY
VQFGDADGSP FYDILSKYTK VTWVKEKNIA DYRKELAEYN LVIIGFHKNN DSPWKSYKFS
DTELFWLQEI SKLRTSNTIL SIFAKPYALL DVVNSTTIDA LLIGYQNSEL AQKKAAQAIF
GAIGANGKLP VSVGSTFQEG TGLEVKPIQR LGYSIPEKVG MSSKNLKAVD SLVQIGLDSL
MFPGAQILIA KKGKVIYNKN FGKPTYGSDG KVNKDHIYDL ASLTKILSTL PMIMKMEEEG
NIALNDTFKE LVPEYEDSEL KDVTVLKALS HYGRLPAWIA FYIDTLSEDR KPSPDFYRNH
PAEGFPFKVA DNLYLTSAYK DSIYNRIGRQ DLKSNRYRYS DVGYYVFKKY IEEFYGSSID
ELVDRFFYRP MGLQYTGFNP LGKFKKNQII PTEEDTYFRY QTIQGYVHDM GAAMQGGVGG
HAGLFSNAND VAKIMQMYLQ GGVYGGRRFL NDRTIQKFNT CYFCHKMVRR GVGFDKPQLE
EKGPTCGCVS RKSFGHSGFT GTYTWADPDE ELIYVFLSNR TFPTASNTLL IKSGLRTRIQ
QAIYDSIIN
//
