ID A0A2T0MDG4_9ACTN Unreviewed; 346 AA.
AC A0A2T0MDG4;
DT 18-JUL-2018, integrated into UniProtKB/TrEMBL.
DT 18-JUL-2018, sequence version 1.
DT 27-MAR-2024, entry version 19.
DE SubName: Full=LacI family transcriptional regulator {ECO:0000313|EMBL:PRX55552.1};
GN ORFNames=B0I32_12612 {ECO:0000313|EMBL:PRX55552.1};
OS Nonomuraea fuscirosea.
OC Bacteria; Actinomycetota; Actinomycetes; Streptosporangiales;
OC Streptosporangiaceae; Nonomuraea.
OX NCBI_TaxID=1291556 {ECO:0000313|EMBL:PRX55552.1, ECO:0000313|Proteomes:UP000238312};
RN [1] {ECO:0000313|EMBL:PRX55552.1, ECO:0000313|Proteomes:UP000238312}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CGMCC 4.7104 {ECO:0000313|EMBL:PRX55552.1,
RC ECO:0000313|Proteomes:UP000238312};
RA Whitman W.;
RT "Genomic Encyclopedia of Type Strains, Phase III (KMG-III): the genomes of
RT soil and plant-associated and newly described type strains.";
RL Submitted (MAR-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PRX55552.1}.
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DR EMBL; PVNG01000026; PRX55552.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2T0MDG4; -.
DR OrthoDB; 3510266at2; -.
DR Proteomes; UP000238312; Unassembled WGS sequence.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR CDD; cd01392; HTH_LacI; 1.
DR Gene3D; 3.40.50.2300; -; 2.
DR Gene3D; 1.10.260.40; lambda repressor-like DNA-binding domains; 1.
DR InterPro; IPR000843; HTH_LacI.
DR InterPro; IPR046335; LacI/GalR-like_sensor.
DR InterPro; IPR010982; Lambda_DNA-bd_dom_sf.
DR InterPro; IPR028082; Peripla_BP_I.
DR PANTHER; PTHR30146:SF121; HTH-TYPE TRANSCRIPTIONAL REPRESSOR CYTR; 1.
DR PANTHER; PTHR30146; LACI-RELATED TRANSCRIPTIONAL REPRESSOR; 1.
DR Pfam; PF00356; LacI; 1.
DR Pfam; PF13377; Peripla_BP_3; 1.
DR SMART; SM00354; HTH_LACI; 1.
DR SUPFAM; SSF47413; lambda repressor-like DNA-binding domains; 1.
DR SUPFAM; SSF53822; Periplasmic binding protein-like I; 1.
DR PROSITE; PS50932; HTH_LACI_2; 1.
PE 4: Predicted;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Reference proteome {ECO:0000313|Proteomes:UP000238312};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT DOMAIN 10..52
FT /note="HTH lacI-type"
FT /evidence="ECO:0000259|PROSITE:PS50932"
SQ SEQUENCE 346 AA; 36326 MW; 735BBB5D775D21B5 CRC64;
MAAREGRARA TVRDVAAETG LSIATVSRVL NGQANVAPHT RELVLRAVGR LGDQAPRPRA
APDAHGPVHG GAVYVRCPYV LTDYFGLIVS SVGETIELHG REMILGAGEA AQESAVLPGL
PDRPGVAGAI LILPPEPGEA LVRLRDRGFP FVVIDPRTPP PRDIAAVSAA HFAGGRKLMA
HVTGLGHRRI GIIGGPVTWL PSEARLAGYT ASLADAGVLQ APELLRHVPE PNIEQGYLAA
GELLDLPERP TALVAFNDKT AVGALRAAAE RRLSVPGDLS VAGFDDIDVS RATSPPLTTV
RQPLQEMGRM GVTLLMRLLS RHTLEALHVS LGAELVVRGS TGPVRG
//
