ID A0A2T0N8M8_9ACTN Unreviewed; 470 AA.
AC A0A2T0N8M8;
DT 18-JUL-2018, integrated into UniProtKB/TrEMBL.
DT 18-JUL-2018, sequence version 1.
DT 27-MAR-2024, entry version 18.
DE SubName: Full=DNA-binding transcriptional MocR family regulator {ECO:0000313|EMBL:PRX69125.1};
GN ORFNames=B0I32_102182 {ECO:0000313|EMBL:PRX69125.1};
OS Nonomuraea fuscirosea.
OC Bacteria; Actinomycetota; Actinomycetes; Streptosporangiales;
OC Streptosporangiaceae; Nonomuraea.
OX NCBI_TaxID=1291556 {ECO:0000313|EMBL:PRX69125.1, ECO:0000313|Proteomes:UP000238312};
RN [1] {ECO:0000313|EMBL:PRX69125.1, ECO:0000313|Proteomes:UP000238312}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CGMCC 4.7104 {ECO:0000313|EMBL:PRX69125.1,
RC ECO:0000313|Proteomes:UP000238312};
RA Whitman W.;
RT "Genomic Encyclopedia of Type Strains, Phase III (KMG-III): the genomes of
RT soil and plant-associated and newly described type strains.";
RL Submitted (MAR-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: In the C-terminal section; belongs to the class-I
CC pyridoxal-phosphate-dependent aminotransferase family.
CC {ECO:0000256|ARBA:ARBA00005384}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PRX69125.1}.
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DR EMBL; PVNG01000002; PRX69125.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2T0N8M8; -.
DR OrthoDB; 9802328at2; -.
DR Proteomes; UP000238312; Unassembled WGS sequence.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR GO; GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
DR GO; GO:0009058; P:biosynthetic process; IEA:InterPro.
DR CDD; cd00609; AAT_like; 1.
DR CDD; cd07377; WHTH_GntR; 1.
DR Gene3D; 3.90.1150.10; Aspartate Aminotransferase, domain 1; 1.
DR Gene3D; 3.40.640.10; Type I PLP-dependent aspartate aminotransferase-like (Major domain); 1.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR004839; Aminotransferase_I/II.
DR InterPro; IPR015424; PyrdxlP-dep_Trfase.
DR InterPro; IPR015421; PyrdxlP-dep_Trfase_major.
DR InterPro; IPR015422; PyrdxlP-dep_Trfase_small.
DR InterPro; IPR000524; Tscrpt_reg_HTH_GntR.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR PANTHER; PTHR46577; HTH-TYPE TRANSCRIPTIONAL REGULATORY PROTEIN GABR; 1.
DR PANTHER; PTHR46577:SF2; TRANSCRIPTIONAL REGULATORY PROTEIN; 1.
DR Pfam; PF00155; Aminotran_1_2; 1.
DR Pfam; PF00392; GntR; 1.
DR SMART; SM00345; HTH_GNTR; 1.
DR SUPFAM; SSF53383; PLP-dependent transferases; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR PROSITE; PS50949; HTH_GNTR; 1.
PE 3: Inferred from homology;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125, ECO:0000313|EMBL:PRX69125.1};
KW Pyridoxal phosphate {ECO:0000256|ARBA:ARBA00022898};
KW Reference proteome {ECO:0000313|Proteomes:UP000238312};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT DOMAIN 4..70
FT /note="HTH gntR-type"
FT /evidence="ECO:0000259|PROSITE:PS50949"
SQ SEQUENCE 470 AA; 49725 MW; 887CF9A5761DAD80 CRC64;
MNNDSSIAQI AAILREEAER LGPGARLPSS REIMRRHNVS PVTVSRAIGQ LAAEGRVVTR
PGSGAFVAQP VHPTRDAADL SWQTVALGDR VVDDGPITAL LGTAPEGVVP LTGGYLRPGL
RPDEQLAAAA ARAVRRPGAW ARPPLTGLPE LRRWFATQAG GDVTAADALI VSGGQAALTN
AFRALAAPGT PILVETPTYP GALAAAKAAG LRAMAVPMDR DGVRPELLAE AFAMTGARVF
FCQPTLHNPT GATLPVERRE QVLQVARAAG AFVVEDDYAR YLTGQAPPSL ASMDRDGTVV
HIGSLTKILA PSLRVAAVIA RGPAAHRLRA AQLVESFFVA RPLQETALEF VGSPAWRRHL
AAVHAEIMIR RDALAAALAE HMPTAEPHLL PIGGMHLWVR LPADVDEGAL VETARQNGVL
VSPGRMYYPS EPPGPRIRVT HMAAAHLAEL REGVRRLAEA LMITGERAAP
//
