ID   A0A2T0Q4B8_9ACTN        Unreviewed;       356 AA.
AC   A0A2T0Q4B8;
DT   18-JUL-2018, integrated into UniProtKB/TrEMBL.
DT   18-JUL-2018, sequence version 1.
DT   24-JAN-2024, entry version 17.
DE   SubName: Full=Prephenate dehydrogenase {ECO:0000313|EMBL:PRX98655.1};
GN   ORFNames=CLV72_104233 {ECO:0000313|EMBL:PRX98655.1};
OS   Allonocardiopsis opalescens.
OC   Bacteria; Actinomycetota; Actinomycetes; Streptosporangiales;
OC   Allonocardiopsis.
OX   NCBI_TaxID=1144618 {ECO:0000313|EMBL:PRX98655.1, ECO:0000313|Proteomes:UP000237846};
RN   [1] {ECO:0000313|EMBL:PRX98655.1, ECO:0000313|Proteomes:UP000237846}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 45601 {ECO:0000313|EMBL:PRX98655.1,
RC   ECO:0000313|Proteomes:UP000237846};
RA   Goeker M.;
RT   "Genomic Encyclopedia of Archaeal and Bacterial Type Strains, Phase II
RT   (KMG-II): from individual species to whole genera.";
RL   Submitted (MAR-2018) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:PRX98655.1}.
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DR   EMBL; PVZC01000004; PRX98655.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A2T0Q4B8; -.
DR   OrthoDB; 9802008at2; -.
DR   Proteomes; UP000237846; Unassembled WGS sequence.
DR   GO; GO:0070403; F:NAD+ binding; IEA:InterPro.
DR   GO; GO:0008977; F:prephenate dehydrogenase (NAD+) activity; IEA:InterPro.
DR   GO; GO:0004665; F:prephenate dehydrogenase (NADP+) activity; IEA:InterPro.
DR   GO; GO:0006571; P:tyrosine biosynthetic process; IEA:InterPro.
DR   Gene3D; 1.10.3660.10; 6-phosphogluconate dehydrogenase C-terminal like domain; 1.
DR   Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR   InterPro; IPR008927; 6-PGluconate_DH-like_C_sf.
DR   InterPro; IPR045865; ACT-like_dom_sf.
DR   InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR   InterPro; IPR046825; PDH_C.
DR   InterPro; IPR046826; PDH_N.
DR   InterPro; IPR003099; Prephen_DH.
DR   PANTHER; PTHR21363; PREPHENATE DEHYDROGENASE; 1.
DR   PANTHER; PTHR21363:SF0; PREPHENATE DEHYDROGENASE [NADP(+)]; 1.
DR   Pfam; PF20463; PDH_C; 1.
DR   Pfam; PF02153; PDH_N; 1.
DR   SUPFAM; SSF48179; 6-phosphogluconate dehydrogenase C-terminal domain-like; 1.
DR   SUPFAM; SSF55021; ACT-like; 1.
DR   SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
DR   PROSITE; PS51176; PDH_ADH; 1.
PE   4: Predicted;
KW   Oxidoreductase {ECO:0000256|ARBA:ARBA00023002};
KW   Reference proteome {ECO:0000313|Proteomes:UP000237846}.
FT   DOMAIN          4..284
FT                   /note="Prephenate/arogenate dehydrogenase"
FT                   /evidence="ECO:0000259|PROSITE:PS51176"
SQ   SEQUENCE   356 AA;  35747 MW;  2D1693A12F7012F5 CRC64;
     MALERVVVLG AGLIGTSVAL ALRERGVRVW LDDADPATLR LAADLGAGAP LRADPPDRPA
     DVALIAVPPA AVAAVLRSAQ DRQLAHTYTD AASVKAGPLA EAAEHGCDLA TFVPGHPMAG
     RELRGPGAAR ADLFLGRPWA LCPAPKTDAA ALAAVADLAR ACGAEPVVVD AEVHDRAVAL
     VSHAPHVAAA AVAARLAEAD DTALGLAGQG VRDVTRIAAG DPGLWTDILA RNAAPVADVV
     EALAADLAAL AAALRAADPE GLDALLRRGA AGRARIPGKH GGPAPAYALV PVVIPDEPNA
     LARLFGAAGD AGVNIEDVRL EHSPGLPVGV AVLHVRPEAA GRLGAALRDG GWSVHA
//