ID   A0A2T0QF65_9ACTN        Unreviewed;       612 AA.
AC   A0A2T0QF65;
DT   18-JUL-2018, integrated into UniProtKB/TrEMBL.
DT   18-JUL-2018, sequence version 1.
DT   24-JAN-2024, entry version 13.
DE   RecName: Full=beta-N-acetylhexosaminidase {ECO:0000256|ARBA:ARBA00012663};
DE            EC=3.2.1.52 {ECO:0000256|ARBA:ARBA00012663};
GN   ORFNames=CLV72_1011179 {ECO:0000313|EMBL:PRY02576.1};
OS   Allonocardiopsis opalescens.
OC   Bacteria; Actinomycetota; Actinomycetes; Streptosporangiales;
OC   Allonocardiopsis.
OX   NCBI_TaxID=1144618 {ECO:0000313|EMBL:PRY02576.1, ECO:0000313|Proteomes:UP000237846};
RN   [1] {ECO:0000313|EMBL:PRY02576.1, ECO:0000313|Proteomes:UP000237846}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 45601 {ECO:0000313|EMBL:PRY02576.1,
RC   ECO:0000313|Proteomes:UP000237846};
RA   Goeker M.;
RT   "Genomic Encyclopedia of Archaeal and Bacterial Type Strains, Phase II
RT   (KMG-II): from individual species to whole genera.";
RL   Submitted (MAR-2018) to the EMBL/GenBank/DDBJ databases.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=Hydrolysis of terminal non-reducing N-acetyl-D-hexosamine
CC         residues in N-acetyl-beta-D-hexosaminides.; EC=3.2.1.52;
CC         Evidence={ECO:0000256|ARBA:ARBA00001231};
CC   -!- SIMILARITY: Belongs to the glycosyl hydrolase 3 family.
CC       {ECO:0000256|ARBA:ARBA00005336, ECO:0000256|RuleBase:RU361161}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:PRY02576.1}.
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DR   EMBL; PVZC01000001; PRY02576.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A2T0QF65; -.
DR   OrthoDB; 9805821at2; -.
DR   Proteomes; UP000237846; Unassembled WGS sequence.
DR   GO; GO:0004553; F:hydrolase activity, hydrolyzing O-glycosyl compounds; IEA:InterPro.
DR   GO; GO:0005975; P:carbohydrate metabolic process; IEA:InterPro.
DR   Gene3D; 3.40.50.1700; Glycoside hydrolase family 3 C-terminal domain; 1.
DR   Gene3D; 3.20.20.300; Glycoside hydrolase, family 3, N-terminal domain; 1.
DR   InterPro; IPR019800; Glyco_hydro_3_AS.
DR   InterPro; IPR002772; Glyco_hydro_3_C.
DR   InterPro; IPR036881; Glyco_hydro_3_C_sf.
DR   InterPro; IPR001764; Glyco_hydro_3_N.
DR   InterPro; IPR036962; Glyco_hydro_3_N_sf.
DR   InterPro; IPR017853; Glycoside_hydrolase_SF.
DR   PANTHER; PTHR30480:SF13; BETA-HEXOSAMINIDASE; 1.
DR   PANTHER; PTHR30480; BETA-HEXOSAMINIDASE-RELATED; 1.
DR   Pfam; PF00933; Glyco_hydro_3; 1.
DR   Pfam; PF01915; Glyco_hydro_3_C; 1.
DR   PRINTS; PR00133; GLHYDRLASE3.
DR   SUPFAM; SSF51445; (Trans)glycosidases; 1.
DR   SUPFAM; SSF52279; Beta-D-glucan exohydrolase, C-terminal domain; 1.
DR   PROSITE; PS00775; GLYCOSYL_HYDROL_F3; 1.
PE   3: Inferred from homology;
KW   Glycosidase {ECO:0000256|RuleBase:RU361161};
KW   Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000256|RuleBase:RU361161};
KW   Reference proteome {ECO:0000313|Proteomes:UP000237846};
KW   Signal {ECO:0000256|SAM:SignalP}.
FT   SIGNAL          1..29
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT   CHAIN           30..612
FT                   /note="beta-N-acetylhexosaminidase"
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT                   /id="PRO_5015474060"
FT   DOMAIN          64..406
FT                   /note="Glycoside hydrolase family 3 N-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF00933"
FT   DOMAIN          446..612
FT                   /note="Glycoside hydrolase family 3 C-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF01915"
SQ   SEQUENCE   612 AA;  63738 MW;  2E29A831A66E3D31 CRC64;
     MVRRSLRSLL SAGGLAVLVS AGAVIPAQAE PAPGSGGPPD PAALRQVERT ADPDEIAEIV
     AGMTVEQKVG QLFVPHVYGD DAENPDPADA AMNMELFGVE TPAEVVSRYH LGGVIYFEWS
     NNLRGGPEQI AGLSNGLQRA AADSGAGVPL VIGTDQEQGV VTRIREPATT FPGNMALAAG
     RSVLGATTAA YITGAELRAM GINQNYAPTA DVNVNPLNPV IGVRSFSSDP GLAARYSAAQ
     VLGYQAADVT ATTKHFPGHG DTHQDSHLEV PQIDHTREEW ERLDLPPFRA AVDAGIDSVM
     TGHLVVPALD PTGTPATLSE PIITGVLRGE LGFDGVVVTD GLDMEGVRQD YTDEEIAVRA
     VQAGVDMLLK SPEGAFAAQY NAVLAAVDSG EISMERLDAS VVRILTMKYE RGLFDDPYAD
     TGTVDRIVGN RLHQAAAGRI TDRTTTLVSN DGVLPLDAGT TGSVLVTGTL TEPLVAGMAE
     RGVAAEGVGT GLNPTPAQID AAVAAAAGHD LVVVATNRAG DARWAEQREL VNELVATGVP
     VVAVAMRDPY DIAYFTGVDA YLATYSATSA SNRSLLRVLF GEVEPSGRLP VDIPVAGSAT
     EVLYPFGHGL GY
//