ID A0A2T0SA72_9PSEU Unreviewed; 890 AA.
AC A0A2T0SA72;
DT 18-JUL-2018, integrated into UniProtKB/TrEMBL.
DT 18-JUL-2018, sequence version 1.
DT 24-JAN-2024, entry version 16.
DE SubName: Full=Acyl-CoA synthetase (NDP forming) {ECO:0000313|EMBL:PRY30325.1};
GN ORFNames=CLV43_12457 {ECO:0000313|EMBL:PRY30325.1};
OS Umezawaea tangerina.
OC Bacteria; Actinomycetota; Actinomycetes; Pseudonocardiales;
OC Pseudonocardiaceae; Umezawaea.
OX NCBI_TaxID=84725 {ECO:0000313|EMBL:PRY30325.1, ECO:0000313|Proteomes:UP000239494};
RN [1] {ECO:0000313|EMBL:PRY30325.1, ECO:0000313|Proteomes:UP000239494}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 44720 {ECO:0000313|EMBL:PRY30325.1,
RC ECO:0000313|Proteomes:UP000239494};
RA Goeker M.;
RT "Genomic Encyclopedia of Archaeal and Bacterial Type Strains, Phase II
RT (KMG-II): from individual species to whole genera.";
RL Submitted (MAR-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PRY30325.1}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; PVTF01000024; PRY30325.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2T0SA72; -.
DR OrthoDB; 190266at2; -.
DR Proteomes; UP000239494; Unassembled WGS sequence.
DR GO; GO:0016747; F:acyltransferase activity, transferring groups other than amino-acyl groups; IEA:InterPro.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR GO; GO:0046872; F:metal ion binding; IEA:InterPro.
DR CDD; cd04301; NAT_SF; 1.
DR Gene3D; 3.40.630.30; -; 1.
DR Gene3D; 3.30.1490.20; ATP-grasp fold, A domain; 1.
DR Gene3D; 3.30.470.20; ATP-grasp fold, B domain; 1.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR Gene3D; 3.40.50.261; Succinyl-CoA synthetase domains; 2.
DR InterPro; IPR016181; Acyl_CoA_acyltransferase.
DR InterPro; IPR011761; ATP-grasp.
DR InterPro; IPR013815; ATP_grasp_subdomain_1.
DR InterPro; IPR003781; CoA-bd.
DR InterPro; IPR000182; GNAT_dom.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR InterPro; IPR032875; Succ_CoA_lig_flav_dom.
DR InterPro; IPR016102; Succinyl-CoA_synth-like.
DR PANTHER; PTHR43334; ACETATE--COA LIGASE [ADP-FORMING]; 1.
DR PANTHER; PTHR43334:SF1; ACETATE--COA LIGASE [ADP-FORMING]; 1.
DR Pfam; PF00583; Acetyltransf_1; 1.
DR Pfam; PF13549; ATP-grasp_5; 1.
DR Pfam; PF13380; CoA_binding_2; 1.
DR Pfam; PF13607; Succ_CoA_lig; 1.
DR SMART; SM00881; CoA_binding; 1.
DR SUPFAM; SSF55729; Acyl-CoA N-acyltransferases (Nat); 1.
DR SUPFAM; SSF56059; Glutathione synthetase ATP-binding domain-like; 1.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
DR SUPFAM; SSF52210; Succinyl-CoA synthetase domains; 2.
DR PROSITE; PS50975; ATP_GRASP; 1.
DR PROSITE; PS51186; GNAT; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|PROSITE-ProRule:PRU00409};
KW Nucleotide-binding {ECO:0000256|PROSITE-ProRule:PRU00409};
KW Reference proteome {ECO:0000313|Proteomes:UP000239494}.
FT DOMAIN 25..178
FT /note="N-acetyltransferase"
FT /evidence="ECO:0000259|PROSITE:PS51186"
FT DOMAIN 671..707
FT /note="ATP-grasp"
FT /evidence="ECO:0000259|PROSITE:PS50975"
FT REGION 871..890
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 890 AA; 93912 MW; BF093035FD4B72FD CRC64;
MAEVDPYDFP EHWEADVVLS DGGTVHLRPI TPDDGERLLA FHGRLSERTR YFRYFGPYPR
MPKRDLERFS TVDHRDRVAL VASLGDDIVA VGRFDRLDGG DSAEIAFVVQ DGHQGRGLGS
ILLEHLAAAA RERGLGRFVA EVLAENGQMV RVFRDAGYVV SREFEEGVLH LEFAIDPTDQ
SVEVARSREQ AAEARSVHNL LHPRSVAVIG ASTDPTKIGN AVLSNLLAAD FTGPVYPVNA
EHRSVRGVRA YPSVLDIPDD VDLAVVAVPA ASVDEVMDAC LAKGVKALLV VSSGFGETGP
DGRSAERRLA AEARSHGMRV VGPNALGVLN TDPGVRLNAT LAPRLPARGR TGFFCQSGAL
GTAILANAAE RGLGLSTFVS AGNRADVSGN DLLQYWETDP ATDLVLLYLE SFGNPRKFAR
LARRLGRTKP IVAVKSGRHA VTPALAENSV AMDEASVQAL FEQAGVIRVE SLAQLFDTAL
LLAHQPLPRG NRVAVVGNST AIGLLAADTA LAQGLELAGD PVDIGAQGGP EEFAAAVRDA
LLRDDTDALV VVFVPPLAVP GTAYARALRE VVEESGLAKP IASTFLAVEG VPDELAVAGP
GGAPGRGSVP SYPSPERAVL SLSRATRYAR WRSAPQGTFT RPSGIDSDRA SALVTALLAE
GVERVDDDTS VRLLACYGID VVPFRVVTSA DDAVAAAVEL GYPVAMKSTD DRLRHRYDLV
GVRLDLGGEE AVRAAYEALT EVADGPGAYV QRMAPKGISC TLGLQDDPSF GTLLSFGLSG
LVSDLLGDRA YRSVPVSDTD AAALVRAPKA APLLAGYRGD VPADLPALED LVLRLAALAE
DLPEVRSLAL EPVLASAAGA FVSSARIVVG PPPSRNDGGP RRLRSTGIGR
//
