ID   A0A2T0SBX7_9PSEU        Unreviewed;       797 AA.
AC   A0A2T0SBX7;
DT   18-JUL-2018, integrated into UniProtKB/TrEMBL.
DT   18-JUL-2018, sequence version 1.
DT   27-MAR-2024, entry version 15.
DE   SubName: Full=Dimethylglycine oxidase {ECO:0000313|EMBL:PRY30930.1};
GN   ORFNames=CLV43_12332 {ECO:0000313|EMBL:PRY30930.1};
OS   Umezawaea tangerina.
OC   Bacteria; Actinomycetota; Actinomycetes; Pseudonocardiales;
OC   Pseudonocardiaceae; Umezawaea.
OX   NCBI_TaxID=84725 {ECO:0000313|EMBL:PRY30930.1, ECO:0000313|Proteomes:UP000239494};
RN   [1] {ECO:0000313|EMBL:PRY30930.1, ECO:0000313|Proteomes:UP000239494}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 44720 {ECO:0000313|EMBL:PRY30930.1,
RC   ECO:0000313|Proteomes:UP000239494};
RA   Goeker M.;
RT   "Genomic Encyclopedia of Archaeal and Bacterial Type Strains, Phase II
RT   (KMG-II): from individual species to whole genera.";
RL   Submitted (MAR-2018) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the GcvT family.
CC       {ECO:0000256|ARBA:ARBA00008609}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:PRY30930.1}.
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DR   EMBL; PVTF01000023; PRY30930.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A2T0SBX7; -.
DR   OrthoDB; 2055370at2; -.
DR   Proteomes; UP000239494; Unassembled WGS sequence.
DR   GO; GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
DR   Gene3D; 2.40.30.110; Aminomethyltransferase beta-barrel domains; 1.
DR   Gene3D; 3.30.70.1400; Aminomethyltransferase beta-barrel domains; 1.
DR   Gene3D; 3.30.9.10; D-Amino Acid Oxidase, subunit A, domain 2; 1.
DR   Gene3D; 3.50.50.60; FAD/NAD(P)-binding domain; 1.
DR   InterPro; IPR006076; FAD-dep_OxRdtase.
DR   InterPro; IPR036188; FAD/NAD-bd_sf.
DR   InterPro; IPR032503; FAO_M.
DR   InterPro; IPR028896; GCST/YgfZ/DmdA.
DR   InterPro; IPR013977; GCV_T_C.
DR   InterPro; IPR006222; GCV_T_N.
DR   InterPro; IPR029043; GcvT/YgfZ_C.
DR   InterPro; IPR027266; TrmE/GcvT_dom1.
DR   PANTHER; PTHR43757; AMINOMETHYLTRANSFERASE; 1.
DR   PANTHER; PTHR43757:SF2; AMINOMETHYLTRANSFERASE, MITOCHONDRIAL; 1.
DR   Pfam; PF01266; DAO; 1.
DR   Pfam; PF16350; FAO_M; 1.
DR   Pfam; PF01571; GCV_T; 1.
DR   Pfam; PF08669; GCV_T_C; 1.
DR   SUPFAM; SSF101790; Aminomethyltransferase beta-barrel domain; 1.
DR   SUPFAM; SSF54373; FAD-linked reductases, C-terminal domain; 1.
DR   SUPFAM; SSF51905; FAD/NAD(P)-binding domain; 1.
DR   SUPFAM; SSF103025; Folate-binding domain; 1.
DR   PROSITE; PS51257; PROKAR_LIPOPROTEIN; 1.
PE   3: Inferred from homology;
KW   Reference proteome {ECO:0000313|Proteomes:UP000239494}.
FT   DOMAIN          6..358
FT                   /note="FAD dependent oxidoreductase"
FT                   /evidence="ECO:0000259|Pfam:PF01266"
FT   DOMAIN          361..416
FT                   /note="FAD dependent oxidoreductase central"
FT                   /evidence="ECO:0000259|Pfam:PF16350"
FT   DOMAIN          418..689
FT                   /note="Aminomethyltransferase folate-binding"
FT                   /evidence="ECO:0000259|Pfam:PF01571"
FT   DOMAIN          710..789
FT                   /note="Glycine cleavage T-protein C-terminal barrel"
FT                   /evidence="ECO:0000259|Pfam:PF08669"
SQ   SEQUENCE   797 AA;  86326 MW;  77937137CDC63094 CRC64;
     MAGRPRVVIV GAGIVGCALA DELTERGWTD VTVLEQGPLF ATGGSSSHAP GLVFQTTGNK
     TMTEFASYTA RKYGELGCFD AVGGLEVATT PERLTELKRR HGWATAWGVE TSLVSPEECV
     ALHPLIAADK VLGGFHIPTD GLAKPVAAAR AQAERAIARG ATFVPDQQVT AVERSAGRVT
     GVTTRGGTFK ADVVVSCAGM WGPLLGEMVD LTVPLVPMAH QYAKTTALAS GRVGGPILRH
     QDADLYFRGH GDRLGIGAYG HDPMPIDPRE IGDPRFTKSM PSERLFTPED FDDSWAAAVD
     LLPVLAESKV DDGINGLFSF TTDGMPLLGE HPDLDGFWVA EAVWITHSAG VARAVAQWLV
     DGQPEQDLHS ADLNRFEDVQ LSPGYIRERS CRNFVEVYDI LHPLQPMESP RPLRTSPFYE
     RQQALGAVFL EGAGWERPHW YEANADLSEV AEVPARNEWA SRFWSPIAGA EALVTRSRVA
     LFDMTPLKRL EVTGPGALDF LQTMTTNNLA RKPGAVTYTL LLGEDGGVRS DLTVARLADN
     RFQVGANGNL DLDWLGRHLP GDGSVQVRDI TSGTCCIGLW GPLARELVEP ISTVDTRLGY
     FKAQRAYVGH VPVTALRLSY VGELGWELYT TADLGRELWD TLWEAGQSHG VIAAGRGAFN
     SLRLEKGYRS WGTDMTTEHD PHEAGVGFAV RMDKGYFVGR DALAARTRTR KLACLTITDP
     HAVVLGNEPV HVDGAPVGYV TSAAYGYTTG VNIAYAWLPA ELAEPGRAVE VEYFGERVAA
     VVAEEPLFDP KMTRLRS
//