ID   A0A2T0SEZ2_9ACTN        Unreviewed;       501 AA.
AC   A0A2T0SEZ2;
DT   18-JUL-2018, integrated into UniProtKB/TrEMBL.
DT   18-JUL-2018, sequence version 1.
DT   27-MAR-2024, entry version 12.
DE   SubName: Full=Multisubunit sodium/proton antiporter MrpD subunit {ECO:0000313|EMBL:PRY31986.1};
GN   ORFNames=CLV70_102197 {ECO:0000313|EMBL:PRY31986.1};
OS   Pseudosporangium ferrugineum.
OC   Bacteria; Actinomycetota; Actinomycetes; Micromonosporales;
OC   Micromonosporaceae; Pseudosporangium.
OX   NCBI_TaxID=439699 {ECO:0000313|EMBL:PRY31986.1, ECO:0000313|Proteomes:UP000239209};
RN   [1] {ECO:0000313|EMBL:PRY31986.1, ECO:0000313|Proteomes:UP000239209}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 45348 {ECO:0000313|EMBL:PRY31986.1,
RC   ECO:0000313|Proteomes:UP000239209};
RA   Goeker M.;
RT   "Genomic Encyclopedia of Archaeal and Bacterial Type Strains, Phase II
RT   (KMG-II): from individual species to whole genera.";
RL   Submitted (MAR-2018) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|RuleBase:RU000320}; Multi-
CC       pass membrane protein {ECO:0000256|RuleBase:RU000320}.
CC   -!- SIMILARITY: Belongs to the CPA3 antiporters (TC 2.A.63) subunit D
CC       family. {ECO:0000256|ARBA:ARBA00005346}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:PRY31986.1}.
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DR   EMBL; PVZG01000002; PRY31986.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A2T0SEZ2; -.
DR   OrthoDB; 9768329at2; -.
DR   Proteomes; UP000239209; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0008137; F:NADH dehydrogenase (ubiquinone) activity; IEA:InterPro.
DR   GO; GO:0042773; P:ATP synthesis coupled electron transport; IEA:InterPro.
DR   InterPro; IPR003918; NADH_UbQ_OxRdtase.
DR   InterPro; IPR001750; ND/Mrp_mem.
DR   PANTHER; PTHR42703:SF1; NA(+)_H(+) ANTIPORTER SUBUNIT D1; 1.
DR   PANTHER; PTHR42703; NADH DEHYDROGENASE; 1.
DR   Pfam; PF00361; Proton_antipo_M; 1.
DR   PRINTS; PR01437; NUOXDRDTASE4.
PE   3: Inferred from homology;
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000239209};
KW   Transmembrane {ECO:0000256|RuleBase:RU000320, ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        6..22
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        34..54
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        77..98
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        110..130
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        136..154
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        166..187
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        207..232
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        239..260
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        272..293
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        300..320
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        326..348
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        369..387
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        407..430
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        450..471
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          130..417
FT                   /note="NADH:quinone oxidoreductase/Mrp antiporter membrane
FT                   subunit"
FT                   /evidence="ECO:0000259|Pfam:PF00361"
SQ   SEQUENCE   501 AA;  51976 MW;  368BA3AEA11F237E CRC64;
     MTWLVPLPVV MPLLGAAVAM LLRRHPGLQR GVSLVVLGAT LAVAVALLAL TATGEPLTVA
     VGGWAAPMGI VLVADRLAAL MLVVSAAVTL CVLVYSIGQG MAGGNDVTPV AVYHPAYLIL
     TAGVTNAFLA GDLFNLYVGF EILLAASYVL ITMGATRSRI RDGTTYVVVS LLSSLIFLTA
     IGLTYAATGT LNLAQLAGRL DALPDGLQLA LQSMLLLAFG IKAAVFPLSA WLPDSYPTAI
     APVTAVFAGL LTKVGVYAII RTQTLLFPDG PAANVLLVAA LLTMIVGILG AVAQSDIKRL
     LSFTLVSHIG YMLFGIGLAS DAGLSGAIYY VVHHIIIQTT LFLAAGLIER RGGSTSLDRL
     GGLARLTPVL AVLFFLPALN LAGIPPFSGF FGKLGLLQAG VAEGGALAWI LVAGSVVTSL
     LTLYAIGRVW NLAFWRTPRL PVPADRVRAL PRLMVGATLA LVVLGTGLTV VSGPLFDVTG
     RAATELLDRE PYVRAVFGEA P
//