ID   A0A2T0TJW7_9PSEU        Unreviewed;       362 AA.
AC   A0A2T0TJW7;
DT   18-JUL-2018, integrated into UniProtKB/TrEMBL.
DT   18-JUL-2018, sequence version 1.
DT   24-JAN-2024, entry version 17.
DE   SubName: Full=Nitric-oxide synthase {ECO:0000313|EMBL:PRY45808.1};
GN   ORFNames=CLV43_10168 {ECO:0000313|EMBL:PRY45808.1};
OS   Umezawaea tangerina.
OC   Bacteria; Actinomycetota; Actinomycetes; Pseudonocardiales;
OC   Pseudonocardiaceae; Umezawaea.
OX   NCBI_TaxID=84725 {ECO:0000313|EMBL:PRY45808.1, ECO:0000313|Proteomes:UP000239494};
RN   [1] {ECO:0000313|EMBL:PRY45808.1, ECO:0000313|Proteomes:UP000239494}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 44720 {ECO:0000313|EMBL:PRY45808.1,
RC   ECO:0000313|Proteomes:UP000239494};
RA   Goeker M.;
RT   "Genomic Encyclopedia of Archaeal and Bacterial Type Strains, Phase II
RT   (KMG-II): from individual species to whole genera.";
RL   Submitted (MAR-2018) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:PRY45808.1}.
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DR   EMBL; PVTF01000001; PRY45808.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A2T0TJW7; -.
DR   Proteomes; UP000239494; Unassembled WGS sequence.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0004517; F:nitric-oxide synthase activity; IEA:InterPro.
DR   GO; GO:0006809; P:nitric oxide biosynthetic process; IEA:InterPro.
DR   Gene3D; 3.90.440.10; Nitric Oxide Synthase;Heme Domain;Chain A domain 2; 1.
DR   InterPro; IPR044943; NOS_dom_1.
DR   InterPro; IPR044940; NOS_dom_2.
DR   InterPro; IPR044944; NOS_dom_3.
DR   InterPro; IPR004030; NOS_N.
DR   InterPro; IPR036119; NOS_N_sf.
DR   PANTHER; PTHR43410; NITRIC OXIDE SYNTHASE OXYGENASE; 1.
DR   PANTHER; PTHR43410:SF1; NITRIC OXIDE SYNTHASE OXYGENASE; 1.
DR   Pfam; PF02898; NO_synthase; 1.
DR   SUPFAM; SSF56512; Nitric oxide (NO) synthase oxygenase domain; 1.
PE   4: Predicted;
KW   Heme {ECO:0000256|ARBA:ARBA00022617}; Iron {ECO:0000256|ARBA:ARBA00023004};
KW   Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW   Oxidoreductase {ECO:0000256|ARBA:ARBA00023002};
KW   Reference proteome {ECO:0000313|Proteomes:UP000239494}.
FT   DOMAIN          11..301
FT                   /note="Nitric oxide synthase (NOS)"
FT                   /evidence="ECO:0000259|Pfam:PF02898"
FT   REGION          297..362
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        342..362
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   362 AA;  39813 MW;  A4DF7389C4835B98 CRC64;
     MFHIAHPEAG AIGTRLAAVR AEVAQTGTYR HTTQELSYGA RIAMRDSGWC TSGLPWRRLK
     VRDLRGLRNA AAVANECVEH LRLATNGGEI RPLVTVFAPD SPSGPGPCVW NEQLIRYAGY
     SDGIGDPRYA AFTDAVQGMG WKAPTMRSRF DVLPLVVETA HEGPRLFTLP PEVVHEVPIE
     HPDLPWFGGL GLRWHAVPVI GNMRLSIGGV SYPAAPFNSW FVGSEIGTRS LGDENGYAAA
     KPVAQALGLD TTSERTLWRD RAVVELNRAV LHSFDRAEVT ITDHHAESQH RLSWLRARQR
     HSGNRPTFRL DPGSAQRART GGPARFSASE SETTRPQSPG RLAELLRHHN DRSSGLHSDD
     SR
//