ID   A0A2T0TK86_9PSEU        Unreviewed;       656 AA.
AC   A0A2T0TK86;
DT   18-JUL-2018, integrated into UniProtKB/TrEMBL.
DT   18-JUL-2018, sequence version 1.
DT   27-MAR-2024, entry version 16.
DE   SubName: Full=Acetoacetyl-CoA synthetase {ECO:0000313|EMBL:PRY46086.1};
GN   ORFNames=CLV43_101351 {ECO:0000313|EMBL:PRY46086.1};
OS   Umezawaea tangerina.
OC   Bacteria; Actinomycetota; Actinomycetes; Pseudonocardiales;
OC   Pseudonocardiaceae; Umezawaea.
OX   NCBI_TaxID=84725 {ECO:0000313|EMBL:PRY46086.1, ECO:0000313|Proteomes:UP000239494};
RN   [1] {ECO:0000313|EMBL:PRY46086.1, ECO:0000313|Proteomes:UP000239494}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 44720 {ECO:0000313|EMBL:PRY46086.1,
RC   ECO:0000313|Proteomes:UP000239494};
RA   Goeker M.;
RT   "Genomic Encyclopedia of Archaeal and Bacterial Type Strains, Phase II
RT   (KMG-II): from individual species to whole genera.";
RL   Submitted (MAR-2018) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:PRY46086.1}.
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DR   EMBL; PVTF01000001; PRY46086.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A2T0TK86; -.
DR   OrthoDB; 9803968at2; -.
DR   Proteomes; UP000239494; Unassembled WGS sequence.
DR   GO; GO:0030729; F:acetoacetate-CoA ligase activity; IEA:InterPro.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0006629; P:lipid metabolic process; IEA:InterPro.
DR   CDD; cd05943; AACS; 1.
DR   Gene3D; 3.30.300.30; -; 1.
DR   Gene3D; 3.40.50.12780; N-terminal domain of ligase-like; 1.
DR   InterPro; IPR005914; Acac_CoA_synth.
DR   InterPro; IPR032387; ACAS_N.
DR   InterPro; IPR045851; AMP-bd_C_sf.
DR   InterPro; IPR020845; AMP-binding_CS.
DR   InterPro; IPR000873; AMP-dep_Synth/Lig_com.
DR   InterPro; IPR042099; ANL_N_sf.
DR   NCBIfam; TIGR01217; ac_ac_CoA_syn; 1.
DR   PANTHER; PTHR42921; ACETOACETYL-COA SYNTHETASE; 1.
DR   PANTHER; PTHR42921:SF1; ACETOACETYL-COA SYNTHETASE; 1.
DR   Pfam; PF16177; ACAS_N; 1.
DR   Pfam; PF00501; AMP-binding; 1.
DR   SUPFAM; SSF56801; Acetyl-CoA synthetase-like; 1.
DR   PROSITE; PS00455; AMP_BINDING; 1.
PE   4: Predicted;
KW   ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW   Ligase {ECO:0000256|ARBA:ARBA00022598};
KW   Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW   Reference proteome {ECO:0000313|Proteomes:UP000239494}.
FT   DOMAIN          42..98
FT                   /note="Acetyl-coenzyme A synthetase N-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF16177"
FT   DOMAIN          108..475
FT                   /note="AMP-dependent synthetase/ligase"
FT                   /evidence="ECO:0000259|Pfam:PF00501"
SQ   SEQUENCE   656 AA;  71147 MW;  659A24BB2F67A46C CRC64;
     MTDTHAEAEL LWRPDPDRVA DSRIAAFRDW LRAERGLDLA DYAELWTWST TDLEAFWGAI
     AEFFDVAFHT PPERVLGAAT MPGAQWFPGA TLNYAEHALR PGPGRADDDL AVIFHREDGL
     AENLTYGELR RRVAAVRAGL VALGVAKGDR VVALVPNSPE ALIAFLAAAS LGATWSSCSP
     DFGARAISDR FTQIEPTVLI AVDGYRYNGR AFDVRPTVDK LRSEIGSLKA TVLVDYTGGA
     LPDAVGWADL LAEHDGAPMA YEPVPFDHPL WVLYSSGTTG LPKGIVQGHG GIVLEHLKML
     GLHADLGPGD RFFWFTTTGW MMWNYVIAGL LVGTTVVLFD GSPGYPDLNA LWHLAEQHRV
     TYFGTSAPYI QSCLKEELRP GERYDLTGLR VVGSTGAPLT PEGFRWIADA IGEDVQIASV
     SGGTDLCTAF VCAAPDLPVW LGELSCRALG AAVTAYDEAG HEVVDQVGEL VVTKPMPSMP
     VFFWGDDDGS RLREAYFEDF PGVWRHGDWI RITPRGSSVI YGRSDSTLNR GGVRMGTSEF
     YRVVEAVPGV ADSLVIDTSG AGLTDGQLLC FLVLADGTAL EDVEPTLRKD LRTNLSPRHV
     PDRFITVTEI PRTLNGKKCE VPVKKILAGT PPTSAVSLDA LRNPDSLTPF LDLAPN
//