ID A0A2T0TKH3_9PSEU Unreviewed; 400 AA.
AC A0A2T0TKH3;
DT 18-JUL-2018, integrated into UniProtKB/TrEMBL.
DT 18-JUL-2018, sequence version 1.
DT 27-MAR-2024, entry version 21.
DE RecName: Full=DNA-directed DNA polymerase {ECO:0000256|ARBA:ARBA00012417};
DE EC=2.7.7.7 {ECO:0000256|ARBA:ARBA00012417};
GN ORFNames=CLV43_101494 {ECO:0000313|EMBL:PRY46222.1};
OS Umezawaea tangerina.
OC Bacteria; Actinomycetota; Actinomycetes; Pseudonocardiales;
OC Pseudonocardiaceae; Umezawaea.
OX NCBI_TaxID=84725 {ECO:0000313|EMBL:PRY46222.1, ECO:0000313|Proteomes:UP000239494};
RN [1] {ECO:0000313|EMBL:PRY46222.1, ECO:0000313|Proteomes:UP000239494}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 44720 {ECO:0000313|EMBL:PRY46222.1,
RC ECO:0000313|Proteomes:UP000239494};
RA Goeker M.;
RT "Genomic Encyclopedia of Archaeal and Bacterial Type Strains, Phase II
RT (KMG-II): from individual species to whole genera.";
RL Submitted (MAR-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PRY46222.1}.
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DR EMBL; PVTF01000001; PRY46222.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2T0TKH3; -.
DR OrthoDB; 9809531at2; -.
DR Proteomes; UP000239494; Unassembled WGS sequence.
DR GO; GO:0008408; F:3'-5' exonuclease activity; IEA:InterPro.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR GO; GO:0003887; F:DNA-directed DNA polymerase activity; IEA:UniProtKB-KW.
DR GO; GO:0006260; P:DNA replication; IEA:UniProtKB-KW.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR004622; DNA_pol_HolB.
DR InterPro; IPR027417; P-loop_NTPase.
DR NCBIfam; TIGR00678; holB; 1.
DR PANTHER; PTHR11669:SF70; POSSIBLE DNA POLYMERASE; 1.
DR PANTHER; PTHR11669; REPLICATION FACTOR C / DNA POLYMERASE III GAMMA-TAU SUBUNIT; 1.
DR Pfam; PF13177; DNA_pol3_delta2; 1.
DR SMART; SM00382; AAA; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
PE 4: Predicted;
KW DNA-directed DNA polymerase {ECO:0000256|ARBA:ARBA00022932};
KW Nucleotidyltransferase {ECO:0000256|ARBA:ARBA00022695};
KW Reference proteome {ECO:0000313|Proteomes:UP000239494};
KW Transferase {ECO:0000256|ARBA:ARBA00022932}.
FT DOMAIN 40..183
FT /note="AAA+ ATPase"
FT /evidence="ECO:0000259|SMART:SM00382"
FT REGION 280..315
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 299..315
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 400 AA; 41947 MW; A827E737E04AC852 CRC64;
MNTSVWAEVV GQPAAVEVLS AAAEAAATIV AGGTPAPGTM THAWLFTGPP GSGRSVTAKA
FAAALECTAT DDRPGCGECS GCHTTMAATH ADVRFVAPEG LSISVAEMRA LVQAAARRPT
GGRWQVVIIE DADRLTEGAA NALLKAVEEP PDRTVFLLCA PSDHPEDVSV TIRSRCRIVP
LGTPPPSAIA DVLRSHDGVS ADMAEWAASV CAGHVGRARR LAVDEQVRTR RESVLRIPLA
VRRPQDVFTC ADQLVAAAEG DATTANEARN EDERAALETA MGAGGTGKGT AAATRGAKGA
MKDLEKRQKS RATRTQRDSY DIALVDLAGF YRDVLVTATG SGARLNHPDR AADTRTAAES
WTPESTLRRL EAVLACREAL ETNVKPRIAI DALVTALHHG
//
