ID   A0A2T0TNY6_9BACT        Unreviewed;      1034 AA.
AC   A0A2T0TNY6;
DT   18-JUL-2018, integrated into UniProtKB/TrEMBL.
DT   18-JUL-2018, sequence version 1.
DT   27-MAR-2024, entry version 14.
DE   SubName: Full=Multidrug efflux pump {ECO:0000313|EMBL:PRY47366.1};
GN   ORFNames=CLV58_101434 {ECO:0000313|EMBL:PRY47366.1};
OS   Spirosoma oryzae.
OC   Bacteria; Bacteroidota; Cytophagia; Cytophagales; Cytophagaceae; Spirosoma.
OX   NCBI_TaxID=1469603 {ECO:0000313|EMBL:PRY47366.1, ECO:0000313|Proteomes:UP000238375};
RN   [1] {ECO:0000313|EMBL:PRY47366.1, ECO:0000313|Proteomes:UP000238375}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 28354 {ECO:0000313|EMBL:PRY47366.1,
RC   ECO:0000313|Proteomes:UP000238375};
RA   Goeker M.;
RT   "Genomic Encyclopedia of Archaeal and Bacterial Type Strains, Phase II
RT   (KMG-II): from individual species to whole genera.";
RL   Submitted (MAR-2018) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:PRY47366.1}.
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DR   EMBL; PVTE01000001; PRY47366.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A2T0TNY6; -.
DR   OrthoDB; 9758234at2; -.
DR   Proteomes; UP000238375; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   GO; GO:0022857; F:transmembrane transporter activity; IEA:InterPro.
DR   Gene3D; 3.30.70.1430; Multidrug efflux transporter AcrB pore domain; 2.
DR   Gene3D; 3.30.70.1440; Multidrug efflux transporter AcrB pore domain; 1.
DR   Gene3D; 3.30.70.1320; Multidrug efflux transporter AcrB pore domain like; 1.
DR   Gene3D; 1.20.1640.10; Multidrug efflux transporter AcrB transmembrane domain; 2.
DR   InterPro; IPR027463; AcrB_DN_DC_subdom.
DR   InterPro; IPR001036; Acrflvin-R.
DR   PANTHER; PTHR32063; -; 1.
DR   PANTHER; PTHR32063:SF28; BLR2861 PROTEIN; 1.
DR   Pfam; PF00873; ACR_tran; 1.
DR   PRINTS; PR00702; ACRIFLAVINRP.
DR   SUPFAM; SSF82866; Multidrug efflux transporter AcrB transmembrane domain; 2.
PE   4: Predicted;
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        12..34
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        334..353
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        360..380
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        386..411
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        431..451
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        463..487
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        527..547
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        857..875
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        882..902
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        908..932
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        957..979
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        985..1011
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
SQ   SEQUENCE   1034 AA;  114008 MW;  A11D9E08F67852BD CRC64;
     MSLPELSLNR PVLAMVMSIV IVLFGVIGFT FLGVREYPAI DPPVITVRTN YTGANPDIVE
     SQITEPIEKS LNSVEGIRTI SSNSALGAST ITVEFNLDVD LERAANDVRD KVAQAQRQLP
     QDIDAPPVVT KADANSDPII FMTVQSTTRN PTQLSDYAEN VLQERLQTIP GVSQANIYGL
     KRQAMRLWID PIKLSAYRLT SQDIQAALNA QNVELPSGKV YGNTTELTVK AVGRLTTEED
     FNNLILRQTA NQIVRFKDVG YATLGAENEE TISKQNGAVG VILVLIPQPG ANYVSIADEF
     YKRFDALKKD LPKDIIVSIG IDRSTFIRRA IEEVGETLLL SFVLVVLVIY LFFRDWLIAF
     RPLIDIPVSL IGAFFIMYVA DFSINVLTLL GIVLATGLVV DDGIVVTENI YKKIEQGMDT
     QQAAKEGSNE IFFAVLATSI TLAVVFLPII FLEGFVGRLF REFGIVVAGA VLISAFVSLT
     LTPVLSVKMT AKDHSKRSWF YQKTEPFFQW LDDSYRQSLD TFMKKRGWAF VMIAACLLLI
     VGLGSLLKSE LAPLEDRSRT RIAITSPEGT SYESQANVTD RVMQFVLDSI PETRLAFSVV
     APGFSGAGAV NSSFVIVNLS EPTERTRSQQ DIVDYITKNL KKFSEARMFA TQDQTIQVGR
     GGGLPVQFVL QNLNFDKLRQ KLPLFLDEVA KDPTFQNSDV DLKFNKPELN ISIDREKATN
     LGISVQDVAQ TLQLALSNRR LAYFLMNGKQ YQVIGQVDRR DRDAPDKLQS FYVRSNQGEL
     IQLDNLVKFQ EVSSPPQVYH YNRFKSATVS ASLAPGKTIG DGVAAMNAIA ARVLDQSFQT
     ALSGPSRDYA ESSSNTLFAF GLALVLVYLI LAAQFDSFID PLIIMITVPL ALAGAVFSLW
     MFNQTLNIFS QIGIIMLVGL VTKNGILIVE FANEQRLTGK NKFEAAVESA ALRLRPILMT
     TLVAAFGALP LALALGAASK SRVPLGIVIV GGLLFSLVLT LYVVPVIYTY MSRRKDVEPE
     KPVSEPTQHR EVVV
//