ID   A0A2T0UXH7_9MICO        Unreviewed;       394 AA.
AC   A0A2T0UXH7;
DT   18-JUL-2018, integrated into UniProtKB/TrEMBL.
DT   18-JUL-2018, sequence version 1.
DT   27-MAR-2024, entry version 18.
DE   SubName: Full=Signal transduction histidine kinase {ECO:0000313|EMBL:PRY62639.1};
GN   ORFNames=BCF74_10475 {ECO:0000313|EMBL:PRY62639.1};
OS   Knoellia remsis.
OC   Bacteria; Actinomycetota; Actinomycetes; Micrococcales; Intrasporangiaceae;
OC   Knoellia.
OX   NCBI_TaxID=407159 {ECO:0000313|EMBL:PRY62639.1, ECO:0000313|Proteomes:UP000237822};
RN   [1] {ECO:0000313|EMBL:PRY62639.1, ECO:0000313|Proteomes:UP000237822}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC BAA-1496 {ECO:0000313|EMBL:PRY62639.1,
RC   ECO:0000313|Proteomes:UP000237822};
RA   Goeker M.;
RT   "Genomic Encyclopedia of Archaeal and Bacterial Type Strains, Phase II
RT   (KMG-II): from individual species to whole genera.";
RL   Submitted (MAR-2018) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:PRY62639.1}.
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DR   EMBL; PVTI01000004; PRY62639.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A2T0UXH7; -.
DR   OrthoDB; 5181554at2; -.
DR   Proteomes; UP000237822; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   GO; GO:0016301; F:kinase activity; IEA:UniProtKB-KW.
DR   GO; GO:0016310; P:phosphorylation; IEA:UniProtKB-KW.
DR   Gene3D; 3.30.565.10; Histidine kinase-like ATPase, C-terminal domain; 1.
DR   InterPro; IPR045975; DUF5931.
DR   InterPro; IPR003594; HATPase_C.
DR   InterPro; IPR036890; HATPase_C_sf.
DR   PANTHER; PTHR24421; NITRATE/NITRITE SENSOR PROTEIN NARX-RELATED; 1.
DR   PANTHER; PTHR24421:SF65; SENSOR HISTIDINE KINASE COMP; 1.
DR   Pfam; PF19354; DUF5931; 1.
DR   Pfam; PF02518; HATPase_c; 1.
DR   SUPFAM; SSF55874; ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase; 1.
PE   4: Predicted;
KW   Kinase {ECO:0000313|EMBL:PRY62639.1}; Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000237822};
KW   Transferase {ECO:0000313|EMBL:PRY62639.1};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        58..77
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        83..101
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        113..146
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        158..176
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          29..181
FT                   /note="DUF5931"
FT                   /evidence="ECO:0000259|Pfam:PF19354"
FT   DOMAIN          295..389
FT                   /note="Histidine kinase/HSP90-like ATPase"
FT                   /evidence="ECO:0000259|Pfam:PF02518"
SQ   SEQUENCE   394 AA;  42063 MW;  3C8E8205AD8D860E CRC64;
     MILRGALVGV TDRSVRTGRP EPIVVEAFSR GLDWFRPAAA AYAGWLAWQR HDAMARPWVA
     YVVVAVLMAF SLALLAYRRR TTLLLGVEVL LAVAGIFATL LADRPEAVAS GQFTLPTIWA
     AGCVVGAAVL HGRLGGVVVA ALIAVADVLE VGTPTVTTWH NILLLFLLGG LIGLAVDLAR
     EGLTRYAQVV AERERLRERE RLARVVHDGV LQTLTFIHRR GDELGDGGAE LASLAADQER
     ALRRLVTQDL TDDSRVGVVA AERDLRPLLT AREADRVTVS LPADPVTLPA ERAVELDAAV
     GAALDNVIQH AGPGATAWLL LEERGDDVSV TVRDNGVGDD LDHLMSAEDR GRLGVSQSII
     GRARDLGGTA SVTTRPGGGC RVVITVPRRE KESV
//