ID A0A2T0UZ48_9MICO Unreviewed; 375 AA.
AC A0A2T0UZ48;
DT 18-JUL-2018, integrated into UniProtKB/TrEMBL.
DT 18-JUL-2018, sequence version 1.
DT 24-JAN-2024, entry version 19.
DE SubName: Full=Uroporphyrinogen-III synthase {ECO:0000313|EMBL:PRY63191.1};
GN ORFNames=BCF74_10222 {ECO:0000313|EMBL:PRY63191.1};
OS Knoellia remsis.
OC Bacteria; Actinomycetota; Actinomycetes; Micrococcales; Intrasporangiaceae;
OC Knoellia.
OX NCBI_TaxID=407159 {ECO:0000313|EMBL:PRY63191.1, ECO:0000313|Proteomes:UP000237822};
RN [1] {ECO:0000313|EMBL:PRY63191.1, ECO:0000313|Proteomes:UP000237822}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC BAA-1496 {ECO:0000313|EMBL:PRY63191.1,
RC ECO:0000313|Proteomes:UP000237822};
RA Goeker M.;
RT "Genomic Encyclopedia of Archaeal and Bacterial Type Strains, Phase II
RT (KMG-II): from individual species to whole genera.";
RL Submitted (MAR-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PRY63191.1}.
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DR EMBL; PVTI01000002; PRY63191.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2T0UZ48; -.
DR OrthoDB; 213853at2; -.
DR Proteomes; UP000237822; Unassembled WGS sequence.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-UniRule.
DR GO; GO:0004852; F:uroporphyrinogen-III synthase activity; IEA:InterPro.
DR GO; GO:0000160; P:phosphorelay signal transduction system; IEA:InterPro.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR GO; GO:0006780; P:uroporphyrinogen III biosynthetic process; IEA:InterPro.
DR CDD; cd06578; HemD; 1.
DR CDD; cd00383; trans_reg_C; 1.
DR Gene3D; 3.40.50.10090; -; 2.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR036108; 4pyrrol_syn_uPrphyn_synt_sf.
DR InterPro; IPR003754; 4pyrrol_synth_uPrphyn_synth.
DR InterPro; IPR001867; OmpR/PhoB-type_DNA-bd.
DR InterPro; IPR016032; Sig_transdc_resp-reg_C-effctor.
DR InterPro; IPR039793; UROS/Hem4.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR PANTHER; PTHR40082; BLR5956 PROTEIN; 1.
DR PANTHER; PTHR40082:SF1; BLR5956 PROTEIN; 1.
DR Pfam; PF02602; HEM4; 1.
DR Pfam; PF00486; Trans_reg_C; 1.
DR SMART; SM00862; Trans_reg_C; 1.
DR SUPFAM; SSF46894; C-terminal effector domain of the bipartite response regulators; 1.
DR SUPFAM; SSF69618; HemD-like; 1.
DR PROSITE; PS51755; OMPR_PHOB; 1.
DR PROSITE; PS51257; PROKAR_LIPOPROTEIN; 1.
PE 4: Predicted;
KW DNA-binding {ECO:0000256|PROSITE-ProRule:PRU01091};
KW Reference proteome {ECO:0000313|Proteomes:UP000237822}.
FT DOMAIN 280..374
FT /note="OmpR/PhoB-type"
FT /evidence="ECO:0000259|PROSITE:PS51755"
FT DNA_BIND 280..374
FT /note="OmpR/PhoB-type"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU01091"
SQ SEQUENCE 375 AA; 38749 MW; 8671E49CF32E50E1 CRC64;
MSVERTPPGL SQVLTGCVVL VTADRRSEEL SSALARRGAT VRHAPALTIV PHEHDEDLLL
ATKQLLAAPP DVVVVTTGIG LRGWVEAADA AGLADELVAV LSRARLIARG PKARGAIQAA
GLTADWVAES ETSAEILELL LGEGVSGQRI AVQHHGAGAD GLDTELAAAG ADVQSLVVYR
WGPPPDPDAL VGSVRETAVG EVDAVVFTSA PGAHAWLAAA ESAGVLDAVV ERTAAGSLVV
AAVGPVTAAP LQDKGIRPLV PDRSRLGALV RTLVHHFEES QSAALHTPVG LLQVRRTVAL
LDGHVLPLSP SGAAVLRLLV AADGDVVSRA QVLEVLPGDS VDPHAAEVAV ARLREVAGRE
LVETVVKRGY RLARR
//
