ID A0A2T0X8G8_9RHOB Unreviewed; 329 AA.
AC A0A2T0X8G8;
DT 18-JUL-2018, integrated into UniProtKB/TrEMBL.
DT 18-JUL-2018, sequence version 1.
DT 27-MAR-2024, entry version 13.
DE SubName: Full=5-methyltetrahydrofolate--homocysteine methyltransferase {ECO:0000313|EMBL:PRY95217.1};
GN ORFNames=BCF33_0832 {ECO:0000313|EMBL:PRY95217.1};
OS Hasllibacter halocynthiae.
OC Bacteria; Pseudomonadota; Alphaproteobacteria; Rhodobacterales;
OC Roseobacteraceae; Hasllibacter.
OX NCBI_TaxID=595589 {ECO:0000313|EMBL:PRY95217.1, ECO:0000313|Proteomes:UP000238801};
RN [1] {ECO:0000313|EMBL:PRY95217.1, ECO:0000313|Proteomes:UP000238801}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 29318 {ECO:0000313|EMBL:PRY95217.1,
RC ECO:0000313|Proteomes:UP000238801};
RA Goeker M.;
RT "Genomic Encyclopedia of Archaeal and Bacterial Type Strains, Phase II
RT (KMG-II): from individual species to whole genera.";
RL Submitted (MAR-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the vitamin-B12 dependent methionine synthase
CC family. {ECO:0000256|ARBA:ARBA00010398}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PRY95217.1}.
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DR EMBL; PVTT01000001; PRY95217.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2T0X8G8; -.
DR OrthoDB; 9803687at2; -.
DR Proteomes; UP000238801; Unassembled WGS sequence.
DR GO; GO:0008168; F:methyltransferase activity; IEA:UniProtKB-KW.
DR GO; GO:0032259; P:methylation; IEA:UniProtKB-KW.
DR GO; GO:0042558; P:pteridine-containing compound metabolic process; IEA:InterPro.
DR Gene3D; 3.20.20.20; Dihydropteroate synthase-like; 1.
DR InterPro; IPR011005; Dihydropteroate_synth-like_sf.
DR InterPro; IPR000489; Pterin-binding_dom.
DR PANTHER; PTHR45833; METHIONINE SYNTHASE; 1.
DR PANTHER; PTHR45833:SF1; METHIONINE SYNTHASE; 1.
DR Pfam; PF00809; Pterin_bind; 1.
DR SUPFAM; SSF51717; Dihydropteroate synthetase-like; 1.
DR PROSITE; PS50972; PTERIN_BINDING; 1.
PE 3: Inferred from homology;
KW Cobalt {ECO:0000256|ARBA:ARBA00023285};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Methyltransferase {ECO:0000256|ARBA:ARBA00022603,
KW ECO:0000313|EMBL:PRY95217.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000238801};
KW Transferase {ECO:0000256|ARBA:ARBA00022679, ECO:0000313|EMBL:PRY95217.1}.
FT DOMAIN 21..280
FT /note="Pterin-binding"
FT /evidence="ECO:0000259|PROSITE:PS50972"
FT REGION 309..329
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 329 AA; 34864 MW; 25DC5ED40EB4EF4F CRC64;
MTRTVLESKT KTVVIGFDEP FCVIGERINP TGRSKLNAEL EAGNFETVER DARDQVACGA
MVLDVNSGAV FKNKMAEDPR YADNNFVEPP LMRELVSRVQ AAVDVPICID SSVTGAIEAA
LEVVEGRPLV NSTTGEEEKL EAILPLCAKH KLPVVAISND ESGISEDPDV RFAVARKIVE
RAADHGVPAH DIVVDPLVMP IGAMATAGRQ VFTLVRRLRD ELGVNTTCGA SNVSFGLPNR
HGVNAAFLPM AIGAGMTSAI MNPIRPVEME AVAAANLLMN HDDNGGAWIG LSRTLEKHRA
DGVPFPEAAA AAAAGGGRGG RRGGRRRAS
//
