ID   A0A2T1E9P9_9CYAN        Unreviewed;       448 AA.
AC   A0A2T1E9P9;
DT   18-JUL-2018, integrated into UniProtKB/TrEMBL.
DT   18-JUL-2018, sequence version 1.
DT   27-MAR-2024, entry version 17.
DE   RecName: Full=TIR domain-containing protein {ECO:0000259|PROSITE:PS50104};
GN   ORFNames=C7B82_11470 {ECO:0000313|EMBL:PSB29433.1};
OS   Stenomitos frigidus ULC18.
OC   Bacteria; Cyanobacteriota; Cyanophyceae; Leptolyngbyales; Leptolyngbyaceae;
OC   Stenomitos.
OX   NCBI_TaxID=2107698 {ECO:0000313|EMBL:PSB29433.1, ECO:0000313|Proteomes:UP000239576};
RN   [1] {ECO:0000313|Proteomes:UP000239576}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ULC18 {ECO:0000313|Proteomes:UP000239576};
RA   Moore K., Momper L.;
RL   Submitted (FEB-2018) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|EMBL:PSB29433.1, ECO:0000313|Proteomes:UP000239576}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ULC18 {ECO:0000313|EMBL:PSB29433.1,
RC   ECO:0000313|Proteomes:UP000239576};
RA   Moore K.R., Magnabosco C., Momper L., Gold D.A., Bosak T., Fournier G.P.;
RT   "The ancient ancestry and fast evolution of plastids.";
RL   Submitted (MAR-2018) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:PSB29433.1}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; PVWK01000062; PSB29433.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A2T1E9P9; -.
DR   OrthoDB; 9768004at2; -.
DR   Proteomes; UP000239576; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   GO; GO:0007165; P:signal transduction; IEA:InterPro.
DR   Gene3D; 3.40.50.10140; Toll/interleukin-1 receptor homology (TIR) domain; 1.
DR   InterPro; IPR000157; TIR_dom.
DR   InterPro; IPR035897; Toll_tir_struct_dom_sf.
DR   PANTHER; PTHR46270; ARMADILLO-TYPE FOLD-RELATED; 1.
DR   PANTHER; PTHR46270:SF2; TIR DOMAIN-CONTAINING PROTEIN; 1.
DR   Pfam; PF13676; TIR_2; 1.
DR   SMART; SM00255; TIR; 1.
DR   SUPFAM; SSF52200; Toll/Interleukin receptor TIR domain; 1.
DR   PROSITE; PS50104; TIR; 1.
PE   4: Predicted;
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000239576};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        229..250
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        421..439
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          20..152
FT                   /note="TIR"
FT                   /evidence="ECO:0000259|PROSITE:PS50104"
SQ   SEQUENCE   448 AA;  51404 MW;  C9DAD4113B409593 CRC64;
     MNASTIQTAK QLQTAILHEA GSDVFISYSR KDQSFVRTLS AAFKQLNHDP WVDWEDIQKG
     EEWWKAIQRG IENAHTFVFI MSPDSVKSSV CREEIEYAAA CNKRFLPIVY REGFDQKQVH
     FKLSSHNWLF FREADDFNEA FQELMKAIDT DLEYVRMHTR LLVRALEWQG KAKNPSSLLR
     GLDLEEAQQW LIKRMGKEPL PTNAHVQYIK ASRDTEVARV SARRKARRTV LLTTLLANIV
     LSVAGGSWFY QFRLNEALER IQKEMVQALQ AGRFGTNGDH FAALADLYVP KGSTPIDNPL
     YQEHQKWLTD LHTVFPNAIP RTYKVGSPGK IMWIGDLSRS IAIGRETTDF LEPFKAEHSE
     RKVFDDKITV IMTPYEDELG HWISASGPIK NSAGQIVGGI RVDFTEAYLI QVQAETQKTL
     LVAYLLVAVW LFILSWIILR SLRPIEED
//