ID A0A2T2YBT6_9BACT Unreviewed; 452 AA.
AC A0A2T2YBT6;
DT 18-JUL-2018, integrated into UniProtKB/TrEMBL.
DT 18-JUL-2018, sequence version 1.
DT 24-JAN-2024, entry version 16.
DE RecName: Full=Exodeoxyribonuclease 7 large subunit {ECO:0000256|RuleBase:RU004355};
DE EC=3.1.11.6 {ECO:0000256|RuleBase:RU004355};
GN Name=xseA {ECO:0000313|EMBL:PSR52964.1};
GN ORFNames=AHMF7605_05200 {ECO:0000313|EMBL:PSR52964.1};
OS Adhaeribacter arboris.
OC Bacteria; Bacteroidota; Cytophagia; Cytophagales; Hymenobacteraceae;
OC Adhaeribacter.
OX NCBI_TaxID=2072846 {ECO:0000313|EMBL:PSR52964.1, ECO:0000313|Proteomes:UP000240357};
RN [1] {ECO:0000313|EMBL:PSR52964.1, ECO:0000313|Proteomes:UP000240357}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=HMF7605 {ECO:0000313|EMBL:PSR52964.1,
RC ECO:0000313|Proteomes:UP000240357};
RA Kang H., Kang J., Cha I., Kim H., Joh K.;
RT "Adhaeribacter sp. HMF7605 Genome sequencing and assembly.";
RL Submitted (MAR-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=Exonucleolytic cleavage in either 5'- to 3'- or 3'- to 5'-
CC direction to yield nucleoside 5'-phosphates.; EC=3.1.11.6;
CC Evidence={ECO:0000256|RuleBase:RU004355};
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|RuleBase:RU004355}.
CC -!- SIMILARITY: Belongs to the XseA family.
CC {ECO:0000256|RuleBase:RU004355}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PSR52964.1}.
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DR EMBL; PYFT01000001; PSR52964.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2T2YBT6; -.
DR OrthoDB; 9802795at2; -.
DR Proteomes; UP000240357; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0009318; C:exodeoxyribonuclease VII complex; IEA:InterPro.
DR GO; GO:0008855; F:exodeoxyribonuclease VII activity; IEA:UniProtKB-EC.
DR GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR GO; GO:0006308; P:DNA catabolic process; IEA:InterPro.
DR InterPro; IPR003753; Exonuc_VII_L.
DR InterPro; IPR020579; Exonuc_VII_lsu_C.
DR InterPro; IPR025824; OB-fold_nuc-bd_dom.
DR NCBIfam; TIGR00237; xseA; 1.
DR PANTHER; PTHR30008; EXODEOXYRIBONUCLEASE 7 LARGE SUBUNIT; 1.
DR PANTHER; PTHR30008:SF0; EXODEOXYRIBONUCLEASE 7 LARGE SUBUNIT; 1.
DR Pfam; PF02601; Exonuc_VII_L; 1.
DR Pfam; PF13742; tRNA_anti_2; 1.
PE 3: Inferred from homology;
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Exonuclease {ECO:0000256|ARBA:ARBA00022839, ECO:0000256|RuleBase:RU004355};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000256|RuleBase:RU004355};
KW Nuclease {ECO:0000256|ARBA:ARBA00022722, ECO:0000256|RuleBase:RU004355}.
FT DOMAIN 8..115
FT /note="OB-fold nucleic acid binding"
FT /evidence="ECO:0000259|Pfam:PF13742"
FT DOMAIN 153..441
FT /note="Exonuclease VII large subunit C-terminal"
FT /evidence="ECO:0000259|Pfam:PF02601"
SQ SEQUENCE 452 AA; 51520 MW; D9D437A0C0214DEF CRC64;
MQTSAPLKLS QLNQLIQYAI DGVFREQTYA VIAETSNIKN YQDKRQCYLT LVEKAENSNE
VLASIQAKIW GNCYRTIRNF EEITGQAFKD NIEILFKVRI QFHIYYGLTV LIEEIDCNYT
IGKLALSRQA VLQKLIDQNP DAVQLVNGEF RTRNRQLNFP PVIQKIALIS SAQADGYNDF
VHELYLNKYQ YTFQVDEYFA QVQGNEAANQ ICQKLIQIYQ SQIAYDAVVI VRGGGSQLDF
SAFDSYTVAR AVARFPIPII TGIGHERNES ICDLMARMPT KTPTKAAATI VSHNRAFEEN
LLHLQKIVIS KTNEVLSAQK LILQTLHSKV IRKTHECLNQ QQQRLRPLSG TVIQLINRLV
HNQRFKLAKI TYRLNGSTEA LVKAEQHKLL TIRNTVKLLS PENVLKRGYA IIFRGDTIIK
NAADVRPGDE ITTLFQDSEI ISTITETRST YE
//
