ID A0A2T3ARP9_AMORE Unreviewed; 916 AA.
AC A0A2T3ARP9;
DT 18-JUL-2018, integrated into UniProtKB/TrEMBL.
DT 18-JUL-2018, sequence version 1.
DT 24-JAN-2024, entry version 16.
DE RecName: Full=DNA mismatch repair proteins mutS family domain-containing protein {ECO:0000259|PROSITE:PS00486};
GN ORFNames=M430DRAFT_146566 {ECO:0000313|EMBL:PSS09037.1};
OS Amorphotheca resinae ATCC 22711.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Leotiomycetes;
OC Helotiales; Amorphothecaceae; Amorphotheca.
OX NCBI_TaxID=857342 {ECO:0000313|EMBL:PSS09037.1, ECO:0000313|Proteomes:UP000241818};
RN [1] {ECO:0000313|EMBL:PSS09037.1, ECO:0000313|Proteomes:UP000241818}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 22711 {ECO:0000313|EMBL:PSS09037.1,
RC ECO:0000313|Proteomes:UP000241818};
RX PubMed=29315638; DOI=10.1111/nph.14974;
RA Martino E., Morin E., Grelet G.A., Kuo A., Kohler A., Daghino S.,
RA Barry K.W., Cichocki N., Clum A., Dockter R.B., Hainaut M., Kuo R.C.,
RA LaButti K., Lindahl B.D., Lindquist E.A., Lipzen A., Khouja H.R.,
RA Magnuson J., Murat C., Ohm R.A., Singer S.W., Spatafora J.W., Wang M.,
RA Veneault-Fourrey C., Henrissat B., Grigoriev I.V., Martin F.M., Perotto S.;
RT "Comparative genomics and transcriptomics depict ericoid mycorrhizal fungi
RT as versatile saprotrophs and plant mutualists.";
RL New Phytol. 217:1213-1229(2018).
CC -!- FUNCTION: Component of the post-replicative DNA mismatch repair system
CC (MMR). {ECO:0000256|RuleBase:RU003756}.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC -!- SIMILARITY: Belongs to the DNA mismatch repair MutS family.
CC {ECO:0000256|ARBA:ARBA00006271, ECO:0000256|RuleBase:RU003756}.
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DR EMBL; KZ679017; PSS09037.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2T3ARP9; -.
DR STRING; 857342.A0A2T3ARP9; -.
DR InParanoid; A0A2T3ARP9; -.
DR OrthoDB; 168255at2759; -.
DR Proteomes; UP000241818; Unassembled WGS sequence.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0140664; F:ATP-dependent DNA damage sensor activity; IEA:InterPro.
DR GO; GO:0030983; F:mismatched DNA binding; IEA:InterPro.
DR GO; GO:0006298; P:mismatch repair; IEA:InterPro.
DR CDD; cd03285; ABC_MSH2_euk; 1.
DR Gene3D; 1.10.1420.10; -; 2.
DR Gene3D; 3.40.1170.10; DNA repair protein MutS, domain I; 1.
DR Gene3D; 3.30.420.110; MutS, connector domain; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR011184; DNA_mismatch_repair_Msh2.
DR InterPro; IPR007695; DNA_mismatch_repair_MutS-lik_N.
DR InterPro; IPR000432; DNA_mismatch_repair_MutS_C.
DR InterPro; IPR007861; DNA_mismatch_repair_MutS_clamp.
DR InterPro; IPR007696; DNA_mismatch_repair_MutS_core.
DR InterPro; IPR016151; DNA_mismatch_repair_MutS_N.
DR InterPro; IPR036187; DNA_mismatch_repair_MutS_sf.
DR InterPro; IPR007860; DNA_mmatch_repair_MutS_con_dom.
DR InterPro; IPR032642; Msh2_ATP-bd.
DR InterPro; IPR036678; MutS_con_dom_sf.
DR InterPro; IPR045076; MutS_family.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR11361:SF35; DNA MISMATCH REPAIR PROTEIN MSH2; 1.
DR PANTHER; PTHR11361; DNA MISMATCH REPAIR PROTEIN MUTS FAMILY MEMBER; 1.
DR Pfam; PF01624; MutS_I; 1.
DR Pfam; PF05188; MutS_II; 1.
DR Pfam; PF05192; MutS_III; 1.
DR Pfam; PF05190; MutS_IV; 1.
DR Pfam; PF00488; MutS_V; 1.
DR PIRSF; PIRSF005813; MSH2; 1.
DR SMART; SM00534; MUTSac; 1.
DR SMART; SM00533; MUTSd; 1.
DR SUPFAM; SSF48334; DNA repair protein MutS, domain III; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS00486; DNA_MISMATCH_REPAIR_2; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW DNA damage {ECO:0000256|ARBA:ARBA00022763, ECO:0000256|RuleBase:RU003756};
KW DNA repair {ECO:0000256|RuleBase:RU003756};
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125, ECO:0000256|RuleBase:RU003756};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741,
KW ECO:0000256|RuleBase:RU003756}; Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000241818}.
FT DOMAIN 730..746
FT /note="DNA mismatch repair proteins mutS family"
FT /evidence="ECO:0000259|PROSITE:PS00486"
SQ SEQUENCE 916 AA; 103391 MW; 931B9CE80D8268CF CRC64;
MSSRPELKVD DEGGFIRFFK ALPTKSDDTV RVFDRGDWYT AHGEDAAFIA RTVYKTTSVL
RQLGKNDSTG LPSVTMTITV YRNFLREALF RLGKRIEVWE TEGRGHWKVA KQASPGNLQD
VEEELGGQFD GAPIILAVKV SAKASEARNV GVCFADASVR ELGVSEFLDN DLYSNFESLL
IQLGVKECLV QVDKSEKDVE LAKLKAIIDS CGIAISERSV SDFATKDIDQ DLARILKDEK
ATATLPQTDL KLAMGSAAAL IKYLGVLHDP SNFGQYQLYQ HDLSQFMKLD ASALKALNLM
PGPRDGSKTM SLYGLLNHCK TPVGSRLLSQ WLKQPLMSLE EITKRQQLVE AFVEDTELRQ
TMQEEHLRSI PDLYRLAKRF QRKLANLEDV VRAYQVVIRL PGFIGTLEGV MDEKYRDPLD
EAYTTKLREY AGSLQKLEEM VETTVDLEAM DRHEYIIKPE FDDGLRIIRK KLDKLKYEMD
QEHRLASQDL NQEMDKKLFL ENHKVHGWCM RLTRTEASCI RNKSKYQECS TQKNGVFFTT
QKLQSIRREF DQLSENYNRT QVSLVNEVVS VAASYCPVIE QLAGVLAHLD VIVSFAHCSV
HAPTSYVRPK MHPRGEGNTI LKEARHPCME MQDDVQFITN DVTLKRGSSE FLIITGPNMG
GKSTYIRQIG VIALMAQIGC FVPCSEAELT IFDCILARVG ASDSQLKGVS TFMAEMLETA
NILKSATSES LIIIDELGRG TSTYDGFGLA WAISEHIVKE IGCFSMFATH FHELTALVDS
YPQVQNLHVV AHIDDHGKAK REVTLLYKVE EGVCDQSFGI HVAELVRFPE KVVNMAKRKA
DELEDFTGKH EGTRIEHKKE DVEEGSMLLK EVLVKWKQEC EGKGLSRDEM VASMRQLVQK
DERLLKNPFF QSIKAL
//
