ID A0A2T3YZ66_9HYPO Unreviewed; 1311 AA.
AC A0A2T3YZ66;
DT 18-JUL-2018, integrated into UniProtKB/TrEMBL.
DT 18-JUL-2018, sequence version 1.
DT 27-MAR-2024, entry version 19.
DE RecName: Full=Cyclic nucleotide-binding domain-containing protein {ECO:0008006|Google:ProtNLM};
GN ORFNames=M441DRAFT_148302 {ECO:0000313|EMBL:PTB37848.1};
OS Trichoderma asperellum CBS 433.97.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC Hypocreomycetidae; Hypocreales; Hypocreaceae; Trichoderma.
OX NCBI_TaxID=1042311 {ECO:0000313|EMBL:PTB37848.1, ECO:0000313|Proteomes:UP000240493};
RN [1] {ECO:0000313|EMBL:PTB37848.1, ECO:0000313|Proteomes:UP000240493}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CBS 433.97 {ECO:0000313|EMBL:PTB37848.1,
RC ECO:0000313|Proteomes:UP000240493};
RG DOE Joint Genome Institute;
RA Aerts A., Atanasova L., Chenthamara K., Zhang J., Grujic M., Henrissat B.,
RA Kuo A., Salamov A., Lipzen A., Labutti K., Barry K., Miao Y., Rahimi M.J.,
RA Shen Q., Grigoriev I.V., Kubicek C.P., Druzhinina I.S.;
RT "Multiple horizontal gene transfer events from other fungi enriched the
RT ability of initially mycotrophic Trichoderma (Ascomycota) to feed on dead
RT plant biomass.";
RL Submitted (JUL-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR EMBL; KZ679267; PTB37848.1; -; Genomic_DNA.
DR STRING; 1042311.A0A2T3YZ66; -.
DR OrthoDB; 1330350at2759; -.
DR Proteomes; UP000240493; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0034220; P:monoatomic ion transmembrane transport; IEA:UniProtKB-KW.
DR CDD; cd00038; CAP_ED; 2.
DR CDD; cd09917; F-box_SF; 1.
DR Gene3D; 2.60.120.10; Jelly Rolls; 2.
DR Gene3D; 3.80.10.10; Ribonuclease Inhibitor; 2.
DR InterPro; IPR006214; Bax_inhibitor_1-related.
DR InterPro; IPR018488; cNMP-bd_CS.
DR InterPro; IPR000595; cNMP-bd_dom.
DR InterPro; IPR018490; cNMP-bd_dom_sf.
DR InterPro; IPR036047; F-box-like_dom_sf.
DR InterPro; IPR001810; F-box_dom.
DR InterPro; IPR001611; Leu-rich_rpt.
DR InterPro; IPR006553; Leu-rich_rpt_Cys-con_subtyp.
DR InterPro; IPR032675; LRR_dom_sf.
DR InterPro; IPR014710; RmlC-like_jellyroll.
DR PANTHER; PTHR45638; CYCLIC NUCLEOTIDE-GATED CATION CHANNEL SUBUNIT A; 1.
DR PANTHER; PTHR45638:SF11; CYCLIC NUCLEOTIDE-GATED CATION CHANNEL SUBUNIT A; 1.
DR Pfam; PF01027; Bax1-I; 1.
DR Pfam; PF00027; cNMP_binding; 2.
DR Pfam; PF16643; cNMPbd_u2; 1.
DR Pfam; PF12937; F-box-like; 1.
DR Pfam; PF13516; LRR_6; 2.
DR SMART; SM00100; cNMP; 2.
DR SMART; SM00367; LRR_CC; 6.
DR SUPFAM; SSF51206; cAMP-binding domain-like; 2.
DR SUPFAM; SSF81383; F-box domain; 1.
DR SUPFAM; SSF52047; RNI-like; 1.
DR PROSITE; PS00888; CNMP_BINDING_1; 1.
DR PROSITE; PS00889; CNMP_BINDING_2; 1.
DR PROSITE; PS50042; CNMP_BINDING_3; 2.
DR PROSITE; PS50181; FBOX; 1.
PE 4: Predicted;
KW Ion channel {ECO:0000256|ARBA:ARBA00023303};
KW Ion transport {ECO:0000256|ARBA:ARBA00023065};
KW Ligand-gated ion channel {ECO:0000256|ARBA:ARBA00023286};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000240493};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT TRANSMEM 1054..1072
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1093..1112
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1124..1143
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1155..1178
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1184..1202
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1214..1233
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1245..1262
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 71..188
FT /note="Cyclic nucleotide-binding"
FT /evidence="ECO:0000259|PROSITE:PS50042"
FT DOMAIN 272..384
FT /note="Cyclic nucleotide-binding"
FT /evidence="ECO:0000259|PROSITE:PS50042"
FT DOMAIN 540..589
FT /note="F-box"
FT /evidence="ECO:0000259|PROSITE:PS50181"
FT REGION 1..28
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 197..248
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 481..513
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 699..730
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 484..501
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1311 AA; 143632 MW; D8B0BE30CE03070F CRC64;
MRRSRSPSAP SHYRGTGHHN GNGAESDPVS LIRSFNVENN PTRPMRPSPL TASTIRDMPL
DLVDRIRSFP LFLSASEEFL VAIGNHLKPQ VHGHNDHIIT EGDDAKAMYW LVRGVVAVTS
RDGEAVYAEL KAGAFFGEIG VLMDMPRTAT IVARTKCLLL VLKKEDLQTV MPKFPEMEKA
IRQEAQERLS VLKKKRTERG ATLKSPKSDF VPRPKTTGEV STGETGAIKD GTVIKSKKRK
SPSPSIIEDP ALGSALGSGF VNIRKTLKEL PLFSSLPPDI LHFLGLSVQP KTYPPFTDII
CQGTPGHEIF FVVRGEAEVI HQQPKTNKEA ESLTRSIQKR PRLKTGQYFG EVASLGLSSG
RTATVRSITT VECLMIPGET LDELWSRCSP DIKLQVEQTA WHRYNYRDED VDMTDAGQQE
KTSKSDPPTP ILARLSLPDV EFAAPLKSIS AKVREDSDTM EPKDPDPFLS VDMENLRNRR
RLSIAPPTAQ TEASPTTPTR QNGARPCPPE PSSPVAFTMP DFEFDMPAKR AKTLSHRPVS
LQQSIISDSI LVNIFQYADV GELLRLRQVS SRWKSLVTTS PKLCRYVDLS HYNRRVTDQV
IIDVLAPFIG TRALVMDLNN CFHITDEGFS ALWRACGKNV QKWKMRSLWD VSANQILEMS
ENAKGLEEID WSNCRKVGDN LLGRVVGWVV PEPPPASSKV VISSSGAKGA KGGKGTKAKE
KSGQQSPTPA PGTVIGCAKL KTLNLSYCKH ITDRSMGHLA AHAASRLQSL SLTRCTSITD
AGFQSWAQFK FEKLTQLCLA DCTYLSDNAI VALVNAAKHL THLDLSFCCA LSDTATEVVA
LGLPKLRELR LAFCGSAVSD SSLESVALHL NELEGLSVRG CVRVTGKGLE YILRGCTRLN
WVDVSQCRNL EPWLRAGSVA KWGFDSRASK SESPSVNSWP TTAFDSVLGD LPTPRTMSVA
MLTTPSFFPR PGASLLGRKA RQPGPARIAQ QRLLPAFRTS MRSFHQQAPK KPSSAFFTSR
IASATTRHGF ARSYYQEAAT RQQSVTSGTG LRKLLVGGAI FGGTLVAINT VFNRETREDG
GMPLFEREYL NNTFLHTGLG VGIIGLTARQ MVQTGFVYRL MVTNPWVVGL GGLALSFATM
IGTRSISPDN YIPKYALWTA FNATQAAFVA PMLAFVPMPL LARAGLYTVA MMGALSVVGA
TAKQEKYLYI GGPLLAGAAI IAASGLAPLV IPATAVRTLA FTQNIWLYGG LAVFGGFTLY
DVQKVLHHAR LAQAGVIKRD PVNESISLEL DFLNIFIRMV QILMMNQNRR K
//
