ID   A0A2T3Z190_9HYPO        Unreviewed;      1098 AA.
AC   A0A2T3Z190;
DT   18-JUL-2018, integrated into UniProtKB/TrEMBL.
DT   18-JUL-2018, sequence version 1.
DT   27-MAR-2024, entry version 20.
DE   RecName: Full=Importin N-terminal domain-containing protein {ECO:0000259|PROSITE:PS50166};
GN   ORFNames=M441DRAFT_91222 {ECO:0000313|EMBL:PTB38578.1};
OS   Trichoderma asperellum CBS 433.97.
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC   Hypocreomycetidae; Hypocreales; Hypocreaceae; Trichoderma.
OX   NCBI_TaxID=1042311 {ECO:0000313|EMBL:PTB38578.1, ECO:0000313|Proteomes:UP000240493};
RN   [1] {ECO:0000313|EMBL:PTB38578.1, ECO:0000313|Proteomes:UP000240493}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CBS 433.97 {ECO:0000313|EMBL:PTB38578.1,
RC   ECO:0000313|Proteomes:UP000240493};
RG   DOE Joint Genome Institute;
RA   Aerts A., Atanasova L., Chenthamara K., Zhang J., Grujic M., Henrissat B.,
RA   Kuo A., Salamov A., Lipzen A., Labutti K., Barry K., Miao Y., Rahimi M.J.,
RA   Shen Q., Grigoriev I.V., Kubicek C.P., Druzhinina I.S.;
RT   "Multiple horizontal gene transfer events from other fungi enriched the
RT   ability of initially mycotrophic Trichoderma (Ascomycota) to feed on dead
RT   plant biomass.";
RL   Submitted (JUL-2016) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
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DR   EMBL; KZ679265; PTB38578.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A2T3Z190; -.
DR   STRING; 1042311.A0A2T3Z190; -.
DR   OrthoDB; 22606at2759; -.
DR   Proteomes; UP000240493; Unassembled WGS sequence.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0005634; C:nucleus; IEA:UniProt.
DR   GO; GO:0031267; F:small GTPase binding; IEA:InterPro.
DR   GO; GO:0006606; P:protein import into nucleus; IEA:InterPro.
DR   Gene3D; 1.25.10.10; Leucine-rich Repeat Variant; 1.
DR   InterPro; IPR011989; ARM-like.
DR   InterPro; IPR016024; ARM-type_fold.
DR   InterPro; IPR021133; HEAT_type_2.
DR   InterPro; IPR001494; Importin-beta_N.
DR   InterPro; IPR040122; Importin_beta.
DR   InterPro; IPR034085; TOG.
DR   PANTHER; PTHR10527; IMPORTIN BETA; 1.
DR   PANTHER; PTHR10527:SF6; IMPORTIN-4; 1.
DR   Pfam; PF13513; HEAT_EZ; 1.
DR   Pfam; PF03810; IBN_N; 1.
DR   SMART; SM00913; IBN_N; 1.
DR   SMART; SM01349; TOG; 1.
DR   SUPFAM; SSF48371; ARM repeat; 2.
DR   PROSITE; PS50077; HEAT_REPEAT; 2.
DR   PROSITE; PS50166; IMPORTIN_B_NT; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000240493};
KW   Repeat {ECO:0000256|ARBA:ARBA00022737}.
FT   DOMAIN          24..91
FT                   /note="Importin N-terminal"
FT                   /evidence="ECO:0000259|PROSITE:PS50166"
FT   REPEAT          162..199
FT                   /note="HEAT"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00103"
FT   REPEAT          384..422
FT                   /note="HEAT"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00103"
SQ   SEQUENCE   1098 AA;  120603 MW;  924D3072B7C42B95 CRC64;
     MDKDKLAQLL QASQVPNTEQ VKAVTADLQK NYYSKPESLL ALIEIALTNA DNAVRQLASV
     QALRLVTKFW KRTAQDQKPL VRSHLLEGTL KETSAANRHS LARLVAGIVG EDMEQGDGED
     FLAQLLPLNT SDNVVHREVG SFVLYAMLED DPAHFSDHTD QLLQLFQARI NDDSKEVRMN
     IVRAIGAILM LVDPEEDPQA LKLMQGFVPS LVNILKATVE AGDEESYGAV FDVFHSFIAY
     DSALLNVHLR DLLMFMIELA GNTNAEDDPR SQALGFLIQT VSFRRMKIQA MKDVGAELMV
     KAMHIVIDLD SEDEEDMSPA RVAISLIDQL ANELPPRQVV VPLLEQFPVF ATNQDPRYRM
     AAMLALGNAA EGAPDFISTQ LQPLLPTIIN LLCDSETKVR HAALVGLIHL AEEMADEMVS
     HHQQIIEAVL KNLESASQGP SDKTNISIIR CACGALDTFG DGIDTKIMAQ YGPALIGPMV
     KLLDHNDYGV KAAAASALGA IAASMEKDFQ PYFENVMKSL GNFVMIKDSE DAMNLRSATC
     DSLGRIALAV GPEAFQPYVM DLMKASEEAL GLDNPRLKET SFILWSNLSK VYHEQFDHFL
     DGVFQGIFSS LELEEEELDI PGIDPSQLDD GHIVIGGKRI KVKTPQSEED LTIATGGEAE
     DEWDDIEDLA DLAGGTTAVA MEQEIALDVL GDVISNSCNM NNLETYVEKT IEKVVPFTDH
     DYEGCRKTAI STLWRIYARV FQVWEEGSGV KWEPGMPPKP TPPASIAKIG ETLHEATMTI
     WANDSDRSVV TDINRNVAAT LKACGPAVLT AKDGMLQEVI SVVTLLITRS HPCQLDLGDE
     DEEQEVEDAG SSEYDWLAID TALDVVVGLA AALGPAFGEL WKIFEKPIYK MASSTEDLQR
     STAVGTIAEL VKYTGEAITP YTESIGQALI RRLSDPDALT KSNSAYAIGL LIFNSTDTAK
     TVPIYPQLWE KFEPMLAMRD MHITDNVAGA LSRMILKHAD AGFVAQALPA IVAALPLQEE
     YEENEPIYQA IHSLYDQSNE TVQQLTPQLI GVFEKVLSPP QEQLEPETRQ IISQTVKALY
     GAKPDLFANN PNLLSLVQ
//