ID   A0A2T3ZIK5_9HYPO        Unreviewed;       735 AA.
AC   A0A2T3ZIK5;
DT   18-JUL-2018, integrated into UniProtKB/TrEMBL.
DT   18-JUL-2018, sequence version 1.
DT   24-JAN-2024, entry version 16.
DE   RecName: Full=AP complex subunit beta {ECO:0000256|PIRNR:PIRNR002291};
GN   ORFNames=M441DRAFT_24775 {ECO:0000313|EMBL:PTB44645.1};
OS   Trichoderma asperellum CBS 433.97.
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC   Hypocreomycetidae; Hypocreales; Hypocreaceae; Trichoderma.
OX   NCBI_TaxID=1042311 {ECO:0000313|EMBL:PTB44645.1, ECO:0000313|Proteomes:UP000240493};
RN   [1] {ECO:0000313|EMBL:PTB44645.1, ECO:0000313|Proteomes:UP000240493}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CBS 433.97 {ECO:0000313|EMBL:PTB44645.1,
RC   ECO:0000313|Proteomes:UP000240493};
RG   DOE Joint Genome Institute;
RA   Aerts A., Atanasova L., Chenthamara K., Zhang J., Grujic M., Henrissat B.,
RA   Kuo A., Salamov A., Lipzen A., Labutti K., Barry K., Miao Y., Rahimi M.J.,
RA   Shen Q., Grigoriev I.V., Kubicek C.P., Druzhinina I.S.;
RT   "Multiple horizontal gene transfer events from other fungi enriched the
RT   ability of initially mycotrophic Trichoderma (Ascomycota) to feed on dead
RT   plant biomass.";
RL   Submitted (JUL-2016) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Adaptins are components of the adaptor complexes which link
CC       clathrin to receptors in coated vesicles. Clathrin-associated protein
CC       complexes are believed to interact with the cytoplasmic tails of
CC       membrane proteins, leading to their selection and concentration.
CC       {ECO:0000256|PIRNR:PIRNR002291}.
CC   -!- SIMILARITY: Belongs to the adaptor complexes large subunit family.
CC       {ECO:0000256|ARBA:ARBA00006613, ECO:0000256|PIRNR:PIRNR002291}.
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DR   EMBL; KZ679258; PTB44645.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A2T3ZIK5; -.
DR   STRING; 1042311.A0A2T3ZIK5; -.
DR   OrthoDB; 648032at2759; -.
DR   Proteomes; UP000240493; Unassembled WGS sequence.
DR   GO; GO:0030117; C:membrane coat; IEA:InterPro.
DR   GO; GO:0030276; F:clathrin binding; IEA:InterPro.
DR   GO; GO:0006886; P:intracellular protein transport; IEA:InterPro.
DR   GO; GO:0016192; P:vesicle-mediated transport; IEA:InterPro.
DR   Gene3D; 1.25.10.10; Leucine-rich Repeat Variant; 1.
DR   InterPro; IPR026739; AP_beta.
DR   InterPro; IPR016342; AP_complex_bsu_1_2_4.
DR   InterPro; IPR011989; ARM-like.
DR   InterPro; IPR016024; ARM-type_fold.
DR   InterPro; IPR002553; Clathrin/coatomer_adapt-like_N.
DR   PANTHER; PTHR11134; ADAPTOR COMPLEX SUBUNIT BETA FAMILY MEMBER; 1.
DR   PANTHER; PTHR11134:SF3; AP COMPLEX SUBUNIT BETA; 1.
DR   Pfam; PF01602; Adaptin_N; 1.
DR   PIRSF; PIRSF002291; AP_complex_beta; 1.
DR   SUPFAM; SSF48371; ARM repeat; 1.
PE   3: Inferred from homology;
KW   Membrane {ECO:0000256|PIRNR:PIRNR002291};
KW   Protein transport {ECO:0000256|PIRNR:PIRNR002291};
KW   Reference proteome {ECO:0000313|Proteomes:UP000240493};
KW   Transport {ECO:0000256|PIRNR:PIRNR002291}.
FT   DOMAIN          15..531
FT                   /note="Clathrin/coatomer adaptor adaptin-like N-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF01602"
FT   REGION          639..682
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          702..735
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        641..655
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        710..726
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   735 AA;  80695 MW;  695BA7F5EAE5316F CRC64;
     MAVNRIRGAF AAPRKGETFE LRAGLVSQYA YERKESIQKT IMAMTLGKDV SALFPDVLKN
     IATGDLDQKK LVYLYLMNYA KTHPDLCILA VNTFVQDSED PNPLVRALAI RTMGCIRVDK
     MVDYMEEPLR KTLRDESPYV RKTAAICVAK LFDLNPALCI ENGFIDSLQE MIGDPNPMVV
     ANSVQALAEI SETAPETRAL LVTPPILKKL LMAMNECTEW GRITILTVLA DYAAADVKES
     EHICERVIPQ FQHVNPSVVL AAVKVVFIHM KSINSELVRS YLKKMAPPLV TLVASQPEVQ
     YVALRNIDLL LQAKPDILSK ELRVFFCKYN DPPYVKMQKL EIMVRIANEK NYEQLLAELK
     EYALEVDMDF VRRAIKAIGQ VAIKIEDASA KCVQALEDLL ATKVNYVVQE VVVVIKDILR
     KYPGYEGVIP SLCNYIDELD EANARGSLIW IVGEYAEKIS NAEEILDGFV DTFSEEFTQT
     QLQILTAVVK LFLKKPSGAQ SLVQKVLQEA TTNNDNPDIR DRAYVYWRLL SGDLEVAKNI
     VLSTKPTIST TMTSLPATLL EQLLSELSTL ASVYHKPPEA FVGKGRFGAD EIQRAAIQEQ
     RQNAAENPIA VSVAANGSGS VSQNNIENLL DIDFDGAAPA SHEQNSATGT PDRMQSPATG
     GMADMMSMFD APPAGGSAAP AAAPAGGMND LMNGFEGLNF GGATTSEPLP AAMQLHNAQS
     VSQPKKDSDD LLGLL
//