ID   A0A2T4AMK7_TRIHA        Unreviewed;       589 AA.
AC   A0A2T4AMK7;
DT   18-JUL-2018, integrated into UniProtKB/TrEMBL.
DT   18-JUL-2018, sequence version 1.
DT   27-MAR-2024, entry version 16.
DE   RecName: Full=AMP-dependent synthetase/ligase domain-containing protein {ECO:0008006|Google:ProtNLM};
GN   ORFNames=M431DRAFT_479794 {ECO:0000313|EMBL:PTB58304.1};
OS   Trichoderma harzianum CBS 226.95.
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC   Hypocreomycetidae; Hypocreales; Hypocreaceae; Trichoderma.
OX   NCBI_TaxID=983964 {ECO:0000313|EMBL:PTB58304.1, ECO:0000313|Proteomes:UP000241690};
RN   [1] {ECO:0000313|EMBL:PTB58304.1, ECO:0000313|Proteomes:UP000241690}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CBS 226.95 {ECO:0000313|EMBL:PTB58304.1,
RC   ECO:0000313|Proteomes:UP000241690};
RG   DOE Joint Genome Institute;
RA   Aerts A., Atanasova L., Chenthamara K., Zhang J., Grujic M., Henrissat B.,
RA   Kuo A., Salamov A., Lipzen A., Labutti K., Barry K., Miao Y., Rahimi M.J.,
RA   Shen Q., Grigoriev I.V., Kubicek C.P., Druzhinina I.S.;
RT   "Multiple horizontal gene transfer events from other fungi enriched the
RT   ability of initially mycotrophic Trichoderma (Ascomycota) to feed on dead
RT   plant biomass.";
RL   Submitted (JUL-2016) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; KZ679677; PTB58304.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A2T4AMK7; -.
DR   STRING; 983964.A0A2T4AMK7; -.
DR   OrthoDB; 589104at2759; -.
DR   Proteomes; UP000241690; Unassembled WGS sequence.
DR   CDD; cd04433; AFD_class_I; 1.
DR   Gene3D; 3.30.300.30; -; 1.
DR   Gene3D; 3.40.50.12780; N-terminal domain of ligase-like; 1.
DR   InterPro; IPR025110; AMP-bd_C.
DR   InterPro; IPR045851; AMP-bd_C_sf.
DR   InterPro; IPR020845; AMP-binding_CS.
DR   InterPro; IPR000873; AMP-dep_Synth/Lig_com.
DR   InterPro; IPR042099; ANL_N_sf.
DR   PANTHER; PTHR43201; ACYL-COA SYNTHETASE; 1.
DR   PANTHER; PTHR43201:SF8; FATTY ACID COA SYNTHETASE FAMILY; 1.
DR   Pfam; PF00501; AMP-binding; 1.
DR   Pfam; PF13193; AMP-binding_C; 1.
DR   SUPFAM; SSF56801; Acetyl-CoA synthetase-like; 1.
DR   PROSITE; PS00455; AMP_BINDING; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000241690}.
FT   DOMAIN          63..377
FT                   /note="AMP-dependent synthetase/ligase"
FT                   /evidence="ECO:0000259|Pfam:PF00501"
FT   DOMAIN          445..532
FT                   /note="AMP-binding enzyme C-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF13193"
SQ   SEQUENCE   589 AA;  65568 MW;  E83B7233203F8EFE CRC64;
     MAVGSAREKF PNDLLLVQFL RSAKRCANQR PYIHDHFGYE KSFEELIADI LRMRDLMRQQ
     LPASAFTERG VFKDENPYVA VLTRSGYGFI VAFFATRVLG GAPIPFGSGI LPEEARYFVN
     RSKASCILAG NDCYEKAERI ASISNGPTDS KTISIPIVCD SEPVKEIDVT IDETLNMDPR
     GPGLVIFTSG TTGPPKGAVL PRICMVFQPD APANCQTVCF RPPHWLGGAI SLVEPMLTGK
     HVHILRERAS VENIWKVFRN NQITGTGFTP GVLREMKEWL ETQSEDEQEE YLKAFKKIGV
     IHCAGAMVSP SVLKFWKSRT GLNFNNVYGS TEVGGLATFK CLDGTERSDA IGVAFPGIKV
     KLADGDHGEI CVKSPFMLTQ KRNSANESFQ SYIGDEEKTK AAFDDEGYFK TGDFAELKDG
     EYIFSGRANT DYILFRHYRI PSVQVEVALT ALPYVTEACV LGVPDHEAKQ ICAAVVRLTR
     EQEKLQSRHG ERIIDLARLR ADMNETLPKY MLPVLVKILG PGEEMPQTVS HKPIKNQIIK
     KCFGVEKSWS AENSIPGVEY WGSMPAPEEA DTKLWDWLGL QRADFKAEA
//