ID   A0A2T4AR49_TRIHA        Unreviewed;       575 AA.
AC   A0A2T4AR49;
DT   18-JUL-2018, integrated into UniProtKB/TrEMBL.
DT   18-JUL-2018, sequence version 1.
DT   27-MAR-2024, entry version 13.
DE   RecName: Full=Carboxylic ester hydrolase {ECO:0000256|RuleBase:RU361235};
DE            EC=3.1.1.- {ECO:0000256|RuleBase:RU361235};
GN   ORFNames=M431DRAFT_74923 {ECO:0000313|EMBL:PTB59545.1};
OS   Trichoderma harzianum CBS 226.95.
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC   Hypocreomycetidae; Hypocreales; Hypocreaceae; Trichoderma.
OX   NCBI_TaxID=983964 {ECO:0000313|EMBL:PTB59545.1, ECO:0000313|Proteomes:UP000241690};
RN   [1] {ECO:0000313|EMBL:PTB59545.1, ECO:0000313|Proteomes:UP000241690}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CBS 226.95 {ECO:0000313|EMBL:PTB59545.1,
RC   ECO:0000313|Proteomes:UP000241690};
RG   DOE Joint Genome Institute;
RA   Aerts A., Atanasova L., Chenthamara K., Zhang J., Grujic M., Henrissat B.,
RA   Kuo A., Salamov A., Lipzen A., Labutti K., Barry K., Miao Y., Rahimi M.J.,
RA   Shen Q., Grigoriev I.V., Kubicek C.P., Druzhinina I.S.;
RT   "Multiple horizontal gene transfer events from other fungi enriched the
RT   ability of initially mycotrophic Trichoderma (Ascomycota) to feed on dead
RT   plant biomass.";
RL   Submitted (JUL-2016) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the type-B carboxylesterase/lipase family.
CC       {ECO:0000256|ARBA:ARBA00005964, ECO:0000256|RuleBase:RU361235}.
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DR   EMBL; KZ679676; PTB59545.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A2T4AR49; -.
DR   STRING; 983964.A0A2T4AR49; -.
DR   OrthoDB; 3085104at2759; -.
DR   Proteomes; UP000241690; Unassembled WGS sequence.
DR   GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR   Gene3D; 3.40.50.1820; alpha/beta hydrolase; 1.
DR   InterPro; IPR029058; AB_hydrolase.
DR   InterPro; IPR002018; CarbesteraseB.
DR   InterPro; IPR019826; Carboxylesterase_B_AS.
DR   PANTHER; PTHR11559; CARBOXYLESTERASE; 1.
DR   PANTHER; PTHR11559:SF370; CARBOXYLIC ESTER HYDROLASE-RELATED; 1.
DR   Pfam; PF00135; COesterase; 1.
DR   SUPFAM; SSF53474; alpha/beta-Hydrolases; 1.
DR   PROSITE; PS00122; CARBOXYLESTERASE_B_1; 1.
PE   3: Inferred from homology;
KW   Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000256|RuleBase:RU361235};
KW   Reference proteome {ECO:0000313|Proteomes:UP000241690};
KW   Signal {ECO:0000256|RuleBase:RU361235}.
FT   SIGNAL          1..19
FT                   /evidence="ECO:0000256|RuleBase:RU361235"
FT   CHAIN           20..575
FT                   /note="Carboxylic ester hydrolase"
FT                   /evidence="ECO:0000256|RuleBase:RU361235"
FT                   /id="PRO_5015376162"
FT   DOMAIN          37..515
FT                   /note="Carboxylesterase type B"
FT                   /evidence="ECO:0000259|Pfam:PF00135"
SQ   SEQUENCE   575 AA;  62461 MW;  199B68D02541FAAA CRC64;
     MRSAYVHAIW GLLVHNSLAA LAPSATIPDG DVTYRGINRN GVEAFLNIAY GMSTSGAHRF
     KPPRLHVPVP GSTIYADAYG PTCPQALGGW VAPLSLTNVT RISEDCLNLN IVRPKGTKPD
     DLLPVMIYIH GGSFWAGQNS EITTTPDGLI LESVKNGLPI MHVGMNYRLG FFGFAQSDAL
     KAERSNNAGL RDQRLAMEWV RDNIEHFGGD PSKITVFGQS SGGLAVGMHV LSFGGKQPVP
     FRNAIASSGA LEPGVVSNIT ENAMKAVVDY VGCNETDFHS SDTLLCLRNH SMDSLLQASL
     KTYRSDINVG DIWLPSIDGD FLPECPAALL SQGKFAKNLN VILSWCEDDV TLFTDESIST
     ADDTRNFIAN YVPNLSSGNL DELLSLYPGS DFATNGELSA EFYRSARIFR DIVMTCPALY
     FGEGVAEQNA NTVYFYHWNQ TILGPVLEHL GHPPGMGPIH TAEFAYVFGN LSHYKMDGVP
     FNPSPSDLEL TVRASRSFST FVGVGKTGLP NRNTFRGFQP AFEKPGQTQV FVVGGPDEGL
     SYIDGLQANR ALASQKIRER CSFLNSEDVL KELGT
//