ID   A0A2T4AVK0_TRIHA        Unreviewed;       859 AA.
AC   A0A2T4AVK0;
DT   18-JUL-2018, integrated into UniProtKB/TrEMBL.
DT   18-JUL-2018, sequence version 1.
DT   13-SEP-2023, entry version 14.
DE   RecName: Full=CDC45-like protein {ECO:0008006|Google:ProtNLM};
GN   ORFNames=M431DRAFT_489865 {ECO:0000313|EMBL:PTB61092.1};
OS   Trichoderma harzianum CBS 226.95.
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC   Hypocreomycetidae; Hypocreales; Hypocreaceae; Trichoderma.
OX   NCBI_TaxID=983964 {ECO:0000313|EMBL:PTB61092.1, ECO:0000313|Proteomes:UP000241690};
RN   [1] {ECO:0000313|EMBL:PTB61092.1, ECO:0000313|Proteomes:UP000241690}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CBS 226.95 {ECO:0000313|EMBL:PTB61092.1,
RC   ECO:0000313|Proteomes:UP000241690};
RG   DOE Joint Genome Institute;
RA   Aerts A., Atanasova L., Chenthamara K., Zhang J., Grujic M., Henrissat B.,
RA   Kuo A., Salamov A., Lipzen A., Labutti K., Barry K., Miao Y., Rahimi M.J.,
RA   Shen Q., Grigoriev I.V., Kubicek C.P., Druzhinina I.S.;
RT   "Multiple horizontal gene transfer events from other fungi enriched the
RT   ability of initially mycotrophic Trichoderma (Ascomycota) to feed on dead
RT   plant biomass.";
RL   Submitted (JUL-2016) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC   -!- SIMILARITY: Belongs to the CDC45 family.
CC       {ECO:0000256|ARBA:ARBA00010727}.
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DR   EMBL; KZ679675; PTB61092.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A2T4AVK0; -.
DR   STRING; 983964.A0A2T4AVK0; -.
DR   OrthoDB; 1407079at2759; -.
DR   Proteomes; UP000241690; Unassembled WGS sequence.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0007049; P:cell cycle; IEA:UniProtKB-KW.
DR   GO; GO:0006270; P:DNA replication initiation; IEA:InterPro.
DR   InterPro; IPR003874; CDC45.
DR   PANTHER; PTHR10507; CDC45-RELATED PROTEIN; 1.
DR   PANTHER; PTHR10507:SF0; CELL DIVISION CONTROL PROTEIN 45 HOMOLOG; 1.
DR   Pfam; PF02724; CDC45; 1.
PE   3: Inferred from homology;
KW   Cell cycle {ECO:0000256|ARBA:ARBA00023306};
KW   DNA replication {ECO:0000256|ARBA:ARBA00022705};
KW   Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW   Reference proteome {ECO:0000313|Proteomes:UP000241690}.
FT   REGION          201..299
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          406..433
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          733..813
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        201..218
FT                   /note="Acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        219..237
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        734..772
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        773..803
FT                   /note="Acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   859 AA;  94350 MW;  77C10ED3ED352B2A CRC64;
     MYLPRSLISK LYSHLQNTRH PLSPAVLILV ALEPDALCAC RILTRLLKHD YIPHKIQPVA
     GYSDLEKAGR ELVVPMMESK GGSGGVVVCL GVGGMVDLGP LLGLEPEGEE SPYSGVEVWV
     FDAHRPWNLA NVFGGFPLEP ANQVSSSYQS RSPAGITGGA INRSYNSGKG GIVVFDDGDI
     EGDLMTERDA YLALLDMPDI EEQGDEDSSE DEDDDEAHSG QEESAHAGQK RKSLNEDESS
     DDEEEPPRQR RRSNSSSSIA SSPRRPKPRG LLSIRDPAVL SSDPVEPPSG AQPPPKVSAR
     TLRKRLLRMR QEREAVLHQY YRMGSSFAEP ISSMMYSLAS ELGRDDNDLL WLAIVGVTSM
     ELYGRSSAGV AAPVRSGGGG RPSGWFGVRG ARLRQLLRDE VRRLNPPEMT NGKVAPENNG
     IIPTTARNPE DTGIRLSPEP RFLLIRHWSL YDSMLHSPYL FSRLRTWSEA GIKRLHKLLA
     KMGVSLAQCK QSYTHMDMML KRELRAKLLK YGSLYNLDEM VPAVDTDGKD RAGAKDGWGF
     VRSWGWRATL SAQDVGIIIG ALLEVGQHAQ TLETTSGGPS QVTREVEDES ELTAQGEEYI
     GRFWEAYDAL ENIDALKAGL PTAQFLHRAI YRTGTSLINK KQIKHLRAFR MCVVKDGPDV
     ALFTHPAALT KLALWIGEAL AEQEKESQGK LSHGGRGTPL VVASLNEKRG VYIVVGTGGG
     GGPDSVFMNK ATKQERQSNK EAKAKKKEEA RKAKEKIREE KRAAKRAANQ GNDDNDDDDE
     LETESEASDS SESEDDSDDE DAENDRGYGL NKFGNAFQEV VSETSARVRI DSFEHSVVEV
     KKEDLGGFLE SLSEKAVVG
//