ID   A0A2T4BK17_9HYPO        Unreviewed;       660 AA.
AC   A0A2T4BK17;
DT   18-JUL-2018, integrated into UniProtKB/TrEMBL.
DT   18-JUL-2018, sequence version 1.
DT   24-JAN-2024, entry version 18.
DE   RecName: Full=DNA polymerase alpha subunit B {ECO:0000256|ARBA:ARBA00018596, ECO:0000256|PIRNR:PIRNR018300};
GN   ORFNames=BBK36DRAFT_150702 {ECO:0000313|EMBL:PTB69648.1};
OS   Trichoderma citrinoviride.
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC   Hypocreomycetidae; Hypocreales; Hypocreaceae; Trichoderma.
OX   NCBI_TaxID=58853 {ECO:0000313|EMBL:PTB69648.1, ECO:0000313|Proteomes:UP000241546};
RN   [1] {ECO:0000313|Proteomes:UP000241546}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=TUCIM 6016 {ECO:0000313|Proteomes:UP000241546};
RG   DOE Joint Genome Institute;
RA   Atanasova L., Chenthamara K., Zhang J., Grujic M., Henrissat B., Kuo A.,
RA   Aerts A., Salamov A., Lipzen A., Labutti K., Barry K., Miao Y.,
RA   Rahimi M.J., Shen Q., Grigoriev I.V., Kubicek C.P., Druzhinina I.S.;
RT   "Multiple horizontal gene transfer events from other fungi enriched the
RT   ability of initially mycotrophic Trichoderma (Ascomycota) to feed on dead
RT   plant biomass.";
RL   Submitted (JUL-2016) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Accessory subunit of the DNA polymerase alpha complex (also
CC       known as the alpha DNA polymerase-primase complex) which plays an
CC       essential role in the initiation of DNA synthesis.
CC       {ECO:0000256|PIRNR:PIRNR018300}.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123,
CC       ECO:0000256|PIRNR:PIRNR018300}.
CC   -!- SIMILARITY: Belongs to the DNA polymerase alpha subunit B family.
CC       {ECO:0000256|ARBA:ARBA00007299, ECO:0000256|PIRNR:PIRNR018300}.
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DR   EMBL; KZ680208; PTB69648.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A2T4BK17; -.
DR   OrthoDB; 49016at2759; -.
DR   Proteomes; UP000241546; Unassembled WGS sequence.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR   GO; GO:0006260; P:DNA replication; IEA:UniProtKB-KW.
DR   Gene3D; 3.60.21.60; -; 2.
DR   InterPro; IPR007185; DNA_pol_a/d/e_bsu.
DR   InterPro; IPR016722; DNA_pol_alpha_bsu.
DR   InterPro; IPR013627; Pol_alpha_B_N.
DR   PANTHER; PTHR23061; DNA POLYMERASE 2 ALPHA 70 KDA SUBUNIT; 1.
DR   PANTHER; PTHR23061:SF12; DNA POLYMERASE ALPHA SUBUNIT B; 1.
DR   Pfam; PF04042; DNA_pol_E_B; 1.
DR   Pfam; PF08418; Pol_alpha_B_N; 1.
DR   PIRSF; PIRSF018300; DNA_pol_alph_2; 1.
PE   3: Inferred from homology;
KW   DNA replication {ECO:0000256|ARBA:ARBA00022705,
KW   ECO:0000256|PIRNR:PIRNR018300}; Nucleus {ECO:0000256|PIRNR:PIRNR018300};
KW   Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW   Reference proteome {ECO:0000313|Proteomes:UP000241546}.
FT   DOMAIN          18..256
FT                   /note="DNA polymerase alpha subunit B N-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF08418"
FT   DOMAIN          370..604
FT                   /note="DNA polymerase alpha/delta/epsilon subunit B"
FT                   /evidence="ECO:0000259|Pfam:PF04042"
FT   REGION          72..139
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        72..91
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        117..133
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   660 AA;  71872 MW;  223A2B649FF980B5 CRC64;
     MAADEMQSRF APNGALEPDV LGELQSMARL HDISAEDLYF KWESYCIKMD ADAQAVTLDG
     VRGLKQSIQD ELEKSQRRVQ LKSERKSAPT PRPKAGGRGG GDVFGMLDGL VPSTPGSGAR
     LLNSSSKTPG SGGQQLRRRM EMQRDIPSSP AAGLNEQLKS MQLPATSFAD RQNAGDVVEI
     LNEELPPAEA PIAPFPEPRI KLTAASDQKK TGYKPLAMKL SEASEILDDR IDDFIDLVRE
     HHNLEDSAFG NAATASTTEV VAVGRIASDS LEGKINAASI VLETSRRTGR GLRVPLNLDA
     VRIWSFFPGQ IVALRGSNIT GDEFIVKEIL ELPLLPSAAS SRAALEAHRE KLRGDPDAMD
     SDSEPAPLNI IYAAGPYTAD DNLDYEPLQA LCNQAADTYA DALVLTGPFL DIDHPLIATG
     DFDLPEEASY DPDTANMNTV FKHLVAPALN RLASANPHLT VILVPSVRDV LNKHVSWPQD
     TIPRRELGLP KSVRIVSNPM TLSMNEVVVG LSSQDVLYEL RSEEVSRGAP AGDLMRRLSR
     HLIEQRHFFP VFPPTDRSRL PRTGTEEGLA TGAMLDVSYL KLGEMVSTRP DVLLMPSSLP
     PFAKVVESVL AINPGSLSKR RGPGTYARMT LYPPPLDGEV IDGLISHRVF DRARVEIVRI
//