ID A0A2T4BXR2_TRILO Unreviewed; 1695 AA.
AC A0A2T4BXR2;
DT 18-JUL-2018, integrated into UniProtKB/TrEMBL.
DT 18-JUL-2018, sequence version 1.
DT 08-NOV-2023, entry version 15.
DE SubName: Full=RasGAP protein {ECO:0000313|EMBL:PTB74062.1};
GN ORFNames=M440DRAFT_1424606 {ECO:0000313|EMBL:PTB74062.1};
OS Trichoderma longibrachiatum ATCC 18648.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC Hypocreomycetidae; Hypocreales; Hypocreaceae; Trichoderma.
OX NCBI_TaxID=983965 {ECO:0000313|EMBL:PTB74062.1, ECO:0000313|Proteomes:UP000240760};
RN [1] {ECO:0000313|EMBL:PTB74062.1, ECO:0000313|Proteomes:UP000240760}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 18648 {ECO:0000313|EMBL:PTB74062.1,
RC ECO:0000313|Proteomes:UP000240760};
RG DOE Joint Genome Institute;
RA Aerts A., Atanasova L., Chenthamara K., Zhang J., Grujic M., Henrissat B.,
RA Kuo A., Salamov A., Lipzen A., Labutti K., Barry K., Miao Y., Rahimi M.J.,
RA Shen Q., Grigoriev I.V., Kubicek C.P., Druzhinina I.S.;
RT "Multiple horizontal gene transfer events from other fungi enriched the
RT ability of initially mycotrophic Trichoderma (Ascomycota) to feed on dead
RT plant biomass.";
RL Submitted (JUL-2016) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; KZ679137; PTB74062.1; -; Genomic_DNA.
DR STRING; 983965.A0A2T4BXR2; -.
DR Proteomes; UP000240760; Unassembled WGS sequence.
DR GO; GO:0015629; C:actin cytoskeleton; IEA:UniProt.
DR GO; GO:0006996; P:organelle organization; IEA:UniProt.
DR CDD; cd21206; CH_IQGAP; 1.
DR CDD; cd05127; RasGAP_IQGAP_like; 1.
DR Gene3D; 1.10.418.10; Calponin-like domain; 1.
DR InterPro; IPR001715; CH_dom.
DR InterPro; IPR036872; CH_dom_sf.
DR InterPro; IPR000048; IQ_motif_EF-hand-BS.
DR InterPro; IPR000593; RasGAP_C.
DR InterPro; IPR001936; RasGAP_dom.
DR InterPro; IPR008936; Rho_GTPase_activation_prot.
DR PANTHER; PTHR14149:SF14; PATTERNED EXPRESSION SITE; 1.
DR PANTHER; PTHR14149; RAS GTPASE-ACTIVATING PROTEIN WITH IQ MOTIF; 1.
DR Pfam; PF00307; CH; 1.
DR Pfam; PF00612; IQ; 2.
DR Pfam; PF00616; RasGAP; 1.
DR Pfam; PF03836; RasGAP_C; 1.
DR SMART; SM00033; CH; 1.
DR SMART; SM00015; IQ; 10.
DR SMART; SM00323; RasGAP; 1.
DR SUPFAM; SSF47576; Calponin-homology domain, CH-domain; 1.
DR SUPFAM; SSF48350; GTPase activation domain, GAP; 1.
DR SUPFAM; SSF143885; RGC domain-like; 1.
DR PROSITE; PS50021; CH; 1.
DR PROSITE; PS50096; IQ; 8.
DR PROSITE; PS50018; RAS_GTPASE_ACTIV_2; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000240760}.
FT DOMAIN 277..383
FT /note="Calponin-homology (CH)"
FT /evidence="ECO:0000259|PROSITE:PS50021"
FT DOMAIN 1059..1275
FT /note="Ras-GAP"
FT /evidence="ECO:0000259|PROSITE:PS50018"
FT REGION 1..66
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 80..167
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..63
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 103..117
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 135..149
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1695 AA; 194229 MW; E1AADBF143DFB987 CRC64;
MSSSYRNSPR RQSHAVDLNA ASSSINRNPS TTSSASSGYS YTSDHSTNSQ STSATSVYGS
TGHKRGQSDV IARARFFETG EASSSSAGKG PDNIYGSIRQ SLRPLPRTPT ASSIEAPATP
PHASRPRERG QSIDIGRLSL TQNDGSASPA ATPRPLPPRP TSMFMSRGEP AIPEETAVPP
SRHGHSHSAH IARPDLERLG RSSTSQLRTL SQLAKSEEAE DFSIISPAQE VAGLRGRRKL
QRTDKTAGGR GPRTNYGWEG RNWMDKQRRF LQAYEYLCHI GEAKEWIEDV IQQTLPPIVE
LEEALRDGVT LAEVVESLNP DRRYRIFRNP KLQFRHSDNI AIFFRYLDEV ELPDLFRFEL
IDLYEKKNIP KVIYCIHALS WLLFRKGIVD FRIGNLIGQL EFEHHELEAM QKGLDMLGVN
MPSFGNMGAD FGVPEPEPEP EPEETEEERI DRELAENEAM IIDFQAQLRG ALLRLKLGEM
MQGFWDEEAW LVDLQARIRG HFARQISDYR MQTRKSTILV QSLVRGFLVR RGLKKSDQDR
KAAEPAILAF QSMLRAQKVR NEMQGLKNVM ARCEGPIRAI QAMSKGFLLR KAQTVQQQET
KQATHEVQNL QALARGMLMR NKVSKELRQL DKTTDKVEDL QALARGMLLR YQVSKELRQL
EEHTPMVASL QAAVRATLLR AKIEQQQQDL HSFTDTWTSL QSAIRGRAAR KEQEVLKAEL
AEHVPMIGQL QAAMRAAAVR REVSTLLDGL KEDEPAIIEL QALIRAMFER RRVAAILDAL
DHEEPAVVNL QAQIRGFLYR QYHSALCEEL ASHNAATAEF QAILKAMMER ARIDDLLTEL
LEEEDSIVIF QAAAKAYLIR LRFEEKKRFY EENMKKVIKI QSFVRAKVQG EAYKSLTTGK
NPPVSAVKNF VHLLNDSDFD FNEEVEFERM RKTVVQHVRQ NEMLEQYIDQ LDIKIALLVK
NKITLDEVVR HQHTFGGTSM GLLANSTMAS TNQFDLKALN KSSRKKLESY QQLFFALQTQ
PHYLARLFKH IRVQATPEKE SRRIELLMMS LFGYAQKRRE EYYLLKLIAR SIREEVESTT
SALEYSRGHY FWAKLLANYT RSPRDRKYLR SLLGPLIRDN IIEDPALDLE SDPMQIYRSA
INNEELRTGR PDHRPLDVPR EVAIRDPETR RLFIDHLRDL REICDQLFLA LEEQVHKMPY
GLRFVCSEMF QALRQHFTRE PQESLLQMVS HWLWKFYLQP AVTMPENMGV IEKSLSPLQK
RNLGEVAKVV GQIALGRPFG GENIYLQPLN AFIGESIERL QQITSDLITV PDAERTFDID
EFNDLYAKNK PTLYVKMSDV FAIHNLVAAE LMVMAPTRDD VLREIMQDLG SAKSNENEMS
AAGAADIQMF LTPRLHDLED PEADIKALFM ETKRCVLYII RVQTGANLLE ILVKPITPED
EDKWEALLRE EFSAGSNSRG AYSDAKMADI TSMSYYDLKR TALENIMQLE QMGRITKQNQ
YQDVLNAIAS DIRTQSRRRV QRQRELDGVR LTLANLNEKA KYLEQQRKSY DDYIEQAMKT
LQNKKGRKRF LMPFTKQYNH QRELERSGRV PKFGSYKYSV RALSEKGVLV SWTGTSDREW
DKIDLTISCD QVGVFTIEGT RSHIQIPGAT AQVPIEDMLQ AQFEAHQFMT LFEGNLKLNV
NLLLHLIYRK FYRTQ
//
