ID A0A2T4GHK4_FUSCU Unreviewed; 719 AA.
AC A0A2T4GHK4;
DT 18-JUL-2018, integrated into UniProtKB/TrEMBL.
DT 18-JUL-2018, sequence version 1.
DT 13-SEP-2023, entry version 25.
DE RecName: Full=U3 small nucleolar RNA-associated protein 25 {ECO:0000256|ARBA:ARBA00015422, ECO:0000256|RuleBase:RU365070};
DE Short=U3 snoRNA-associated protein 25 {ECO:0000256|RuleBase:RU365070};
GN ORFNames=FCULG_00009631 {ECO:0000313|EMBL:PTD02975.1}, HYE67_010859
GN {ECO:0000313|EMBL:QPC68628.1};
OS Fusarium culmorum.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC Hypocreomycetidae; Hypocreales; Nectriaceae; Fusarium.
OX NCBI_TaxID=5516 {ECO:0000313|EMBL:PTD02975.1, ECO:0000313|Proteomes:UP000241587};
RN [1] {ECO:0000313|EMBL:PTD02975.1, ECO:0000313|Proteomes:UP000241587}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=PV {ECO:0000313|EMBL:PTD02975.1,
RC ECO:0000313|Proteomes:UP000241587};
RA Schmidt R.;
RT "Fusarium culmorum secondary metabolites in fungal-bacterial-plant
RT interactions.";
RL Submitted (FEB-2018) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:QPC68628.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=Class2-1B {ECO:0000313|EMBL:QPC68628.1};
RA Yuan Z.;
RT "The chromosome-scale genome resource for two endophytic Fusarium species:
RT F. culmorum and F. pseudograminearum.";
RL Submitted (NOV-2020) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: DEAD-box RNA helicase-like protein required for pre-18S rRNA
CC processing, specifically at sites A0, A1, and A2.
CC {ECO:0000256|ARBA:ARBA00002883, ECO:0000256|RuleBase:RU365070}.
CC -!- SUBUNIT: Component of the ribosomal small subunit (SSU) processome
CC composed of at least 40 protein subunits and snoRNA U3.
CC {ECO:0000256|ARBA:ARBA00011192, ECO:0000256|RuleBase:RU365070}.
CC -!- SUBCELLULAR LOCATION: Nucleus, nucleolus
CC {ECO:0000256|ARBA:ARBA00004604, ECO:0000256|RuleBase:RU365070}.
CC -!- SIMILARITY: Belongs to the UTP25 family.
CC {ECO:0000256|ARBA:ARBA00009223, ECO:0000256|RuleBase:RU365070}.
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DR EMBL; PVEM01000016; PTD02975.1; -; Genomic_DNA.
DR EMBL; CP064750; QPC68628.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2T4GHK4; -.
DR OMA; KYFRQTI; -.
DR Proteomes; UP000241587; Unassembled WGS sequence.
DR Proteomes; UP000663297; Chromosome 4.
DR GO; GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.
DR GO; GO:1990904; C:ribonucleoprotein complex; IEA:UniProtKB-KW.
DR GO; GO:0034511; F:U3 snoRNA binding; IEA:InterPro.
DR GO; GO:0006364; P:rRNA processing; IEA:UniProtKB-KW.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR010678; UTP25.
DR PANTHER; PTHR12933; ORF PROTEIN-RELATED; 1.
DR PANTHER; PTHR12933:SF0; U3 SMALL NUCLEOLAR RNA-ASSOCIATED PROTEIN 25 HOMOLOG; 1.
DR Pfam; PF06862; UTP25; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
PE 3: Inferred from homology;
KW Nucleus {ECO:0000256|ARBA:ARBA00023242, ECO:0000256|RuleBase:RU365070};
KW Reference proteome {ECO:0000313|Proteomes:UP000241587};
KW Ribonucleoprotein {ECO:0000256|ARBA:ARBA00023274,
KW ECO:0000256|RuleBase:RU365070};
KW Ribosome biogenesis {ECO:0000256|RuleBase:RU365070};
KW rRNA processing {ECO:0000256|RuleBase:RU365070}.
FT REGION 1..173
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 59..78
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 99..113
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 119..163
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 719 AA; 81954 MW; 7677FA959C16EDEB CRC64;
MPPRGRGGNF RGRGGRGRGR GGRGGKATSR FGPNRRFDGA RLAENDGSES SGSESESAPE
DTVMEDLESE DEDDDEETAS AKPYMALLQS FNNESNAPNS KRRKLDHKES AQSQPGEDSS
SDEEGEEGQD DPEKDIDRAE DEAEDQVEEQ VDDDDDSEDE ENPTDPFDVH FAHPDEDIVA
KRVKSAQEGN WATKRALIQT LRATVTYPAS DAGSEVPKPI AGLDGLQLKQ KLKEISSRKI
GEFSAVQRNL SPLIFNYNDV LFCDRTVRNS DSLRELTCLH ALNHVFKTRD RVIKNNYKLA
KEGQDDDLEL RDQGFTRPKV LFLLPTRNSC LRMVNMIRDL CEPDQQENRK RFDDGYVDKE
ARFGADRPAD FKDLFEGSDD DMFRLGMKFT RKTVKYFSQF YNSDILFASP LGLRMAIGSE
EDKKLDFDFL SSIEMVVVDQ ADALLMQNWE HVEFIFEHLN LQPKDAHGCD FSRVRNWYLE
DWAKYFRQTI ILSAFNTPEL SELLRLHCHN WAGKVRLQPE YPGTLSQLGV KAKQTFSRFQ
SKSVDKDPDA RFEYFTSAII PSLAKRAKDA TGTLIFVPSY LDFVRVRNYF ATSSSVENVT
FGAISEYTDV PEASRARSHF LSGRHRVLLY TERAHHFRRY QFRGVQRVIF YGLPDNPIFY
TEIAGGYLSK SEQDLRLEPG QGTAKVVFSK YDVMKLERIV GSKRVGKMIQ DRGDTFEFI
//
