ID   A0A2T4IBN1_9RHOO        Unreviewed;       416 AA.
AC   A0A2T4IBN1;
DT   18-JUL-2018, integrated into UniProtKB/TrEMBL.
DT   18-JUL-2018, sequence version 1.
DT   27-MAR-2024, entry version 11.
DE   SubName: Full=MBL fold metallo-hydrolase {ECO:0000313|EMBL:PTD95126.1};
GN   ORFNames=C8261_15970 {ECO:0000313|EMBL:PTD95126.1};
OS   Pseudothauera lacus.
OC   Bacteria; Pseudomonadota; Betaproteobacteria; Rhodocyclales; Zoogloeaceae;
OC   Pseudothauera.
OX   NCBI_TaxID=2136175 {ECO:0000313|EMBL:PTD95126.1, ECO:0000313|Proteomes:UP000241193};
RN   [1] {ECO:0000313|EMBL:PTD95126.1, ECO:0000313|Proteomes:UP000241193}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=D20 {ECO:0000313|EMBL:PTD95126.1,
RC   ECO:0000313|Proteomes:UP000241193};
RA   Keele B.F.;
RL   Submitted (MAR-2018) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|EMBL:PTD95126.1, ECO:0000313|Proteomes:UP000241193}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=D20 {ECO:0000313|EMBL:PTD95126.1,
RC   ECO:0000313|Proteomes:UP000241193};
RA   Liang Q.-Y.;
RT   "Thauera lacus sp. nov., isolated from an saline lake in Inner Mongolia,
RT   China.";
RL   Submitted (APR-2018) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:PTD95126.1}.
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DR   EMBL; PZKC01000018; PTD95126.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A2T4IBN1; -.
DR   OrthoDB; 9803916at2; -.
DR   Proteomes; UP000241193; Unassembled WGS sequence.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0004518; F:nuclease activity; IEA:UniProtKB-KW.
DR   CDD; cd07732; metallo-hydrolase-like_MBL-fold; 1.
DR   Gene3D; 3.60.15.10; Ribonuclease Z/Hydroxyacylglutathione hydrolase-like; 2.
DR   InterPro; IPR001279; Metallo-B-lactamas.
DR   InterPro; IPR036866; RibonucZ/Hydroxyglut_hydro.
DR   InterPro; IPR011108; RMMBL.
DR   PANTHER; PTHR43694; RIBONUCLEASE J; 1.
DR   PANTHER; PTHR43694:SF1; RIBONUCLEASE J; 1.
DR   Pfam; PF12706; Lactamase_B_2; 1.
DR   Pfam; PF07521; RMMBL; 1.
DR   SMART; SM00849; Lactamase_B; 1.
DR   SUPFAM; SSF56281; Metallo-hydrolase/oxidoreductase; 1.
PE   4: Predicted;
KW   Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000313|EMBL:PTD95126.1};
KW   Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW   Nuclease {ECO:0000256|ARBA:ARBA00022722};
KW   Reference proteome {ECO:0000313|Proteomes:UP000241193};
KW   Zinc {ECO:0000256|ARBA:ARBA00022833}.
FT   DOMAIN          17..211
FT                   /note="Metallo-beta-lactamase"
FT                   /evidence="ECO:0000259|SMART:SM00849"
SQ   SEQUENCE   416 AA;  45474 MW;  5365AF5798296666 CRC64;
     MSGRVTLTIH RAAHEIGGNC IEVATADGSR VLLDAGRPLD APEGACEGLL PSTLDVGRPV
     AGVLLSHPHQ DHYGLLDELP ASWPVFCGRA SEKLIRLTSG IFGRAPRQSF HNWESGRPFT
     LGPFTVTPLL TDHSAFDAYM LLIEVAGKRL LYSGDFRLHG RKSALVRRLM GSPPASVNAL
     VMEGTNLGSS KPCSSETDLE KRFLALFQAT SGRVFVAWSA QNIDRTVTLY RACKAAGRTL
     VVDLYTAEVM ELVADFGRLP HPSWSNIKVV ITKAFARMYR DTGRGDFVDR MAMHGISADK
     LAETPSKWVV MTRPSLIRDF EKKGVAPNRQ DAWSWSMWHG YLRGGDGSRV QAWFDQGQCL
     ANHIHTSGHA SPDDLRQFAA AINPQALIPV HGVAWDAEAE GFPAVRRLAD GEPATL
//