ID   A0A2T4IDA6_9RHOO        Unreviewed;       942 AA.
AC   A0A2T4IDA6;
DT   18-JUL-2018, integrated into UniProtKB/TrEMBL.
DT   18-JUL-2018, sequence version 1.
DT   27-MAR-2024, entry version 16.
DE   SubName: Full=Diguanylate cyclase {ECO:0000313|EMBL:PTD95740.1};
GN   ORFNames=C8261_13255 {ECO:0000313|EMBL:PTD95740.1};
OS   Pseudothauera lacus.
OC   Bacteria; Pseudomonadota; Betaproteobacteria; Rhodocyclales; Zoogloeaceae;
OC   Pseudothauera.
OX   NCBI_TaxID=2136175 {ECO:0000313|EMBL:PTD95740.1, ECO:0000313|Proteomes:UP000241193};
RN   [1] {ECO:0000313|EMBL:PTD95740.1, ECO:0000313|Proteomes:UP000241193}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=D20 {ECO:0000313|EMBL:PTD95740.1,
RC   ECO:0000313|Proteomes:UP000241193};
RA   Keele B.F.;
RL   Submitted (MAR-2018) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|EMBL:PTD95740.1, ECO:0000313|Proteomes:UP000241193}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=D20 {ECO:0000313|EMBL:PTD95740.1,
RC   ECO:0000313|Proteomes:UP000241193};
RA   Liang Q.-Y.;
RT   "Thauera lacus sp. nov., isolated from an saline lake in Inner Mongolia,
RT   China.";
RL   Submitted (APR-2018) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:PTD95740.1}.
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DR   EMBL; PZKC01000011; PTD95740.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A2T4IDA6; -.
DR   OrthoDB; 9813903at2; -.
DR   Proteomes; UP000241193; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   CDD; cd01949; GGDEF; 1.
DR   CDD; cd01007; PBP2_BvgS_HisK_like; 2.
DR   CDD; cd13708; PBP2_BvgS_like_1; 1.
DR   Gene3D; 3.30.70.270; -; 1.
DR   Gene3D; 3.40.190.10; Periplasmic binding protein-like II; 6.
DR   InterPro; IPR000160; GGDEF_dom.
DR   InterPro; IPR029787; Nucleotide_cyclase.
DR   InterPro; IPR043128; Rev_trsase/Diguanyl_cyclase.
DR   InterPro; IPR001638; Solute-binding_3/MltF_N.
DR   NCBIfam; TIGR00254; GGDEF; 1.
DR   PANTHER; PTHR35936; MEMBRANE-BOUND LYTIC MUREIN TRANSGLYCOSYLASE F; 1.
DR   PANTHER; PTHR35936:SF35; PBPB DOMAIN-CONTAINING PROTEIN; 1.
DR   Pfam; PF00990; GGDEF; 1.
DR   Pfam; PF00497; SBP_bac_3; 3.
DR   SMART; SM00267; GGDEF; 1.
DR   SMART; SM00062; PBPb; 3.
DR   SUPFAM; SSF55073; Nucleotide cyclase; 1.
DR   SUPFAM; SSF53850; Periplasmic binding protein-like II; 3.
DR   PROSITE; PS50887; GGDEF; 1.
PE   4: Predicted;
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000241193};
KW   Signal {ECO:0000256|ARBA:ARBA00022729};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        737..755
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          807..942
FT                   /note="GGDEF"
FT                   /evidence="ECO:0000259|PROSITE:PS50887"
SQ   SEQUENCE   942 AA;  103645 MW;  AB0AEA5650E34717 CRC64;
     MAEGASAAQG RKVLTVGVIA DNEPYSSVDG GTPSGFSIDV LEEVAAHAGL RFSYRAGSWP
     EIYPAFLRGE IDVIDEISFR EERAALMRFT EPYHYRQTVV MHDVNRPLPA LGAVEDLRPY
     RVGVVRDIYY KSELSARGIA VVEYDGLPSL VRALAFGWVD AIVGPEVTLS YHARRGGFGH
     LRVAGSVPMG GLEVEDFRLA VLPANASLLE ALSAGLAAIP PQRMAEMLER WQEFGGQAIS
     APQAYRLSEQ QTAYIRRLGP VRVGLMRDYA PFSFVDGGKV QGLAVDVLER VADLSGMQVV
     TVADRWTVLL DLFQRGEIDV IANISDHPAR REFTRYTRPY HVIPNVVFSR DPTLLYEQPE
     DLRGLRIALG SEVFYEGAVR RQFGDSVVGF SSQQAMFGAL AEGSVDVVLA ALPNGMHWVR
     ELGLTDVRVA GEFSMPGVEG EDLRFGVRPA LEPLARIMDD ALAAISPTEQ RTIENRWLGA
     SAVRGEVMQR RLSFSAAEEA YLAQRGGRLR ACVSPAWMPI EGLDRHGRHA GIGADFLALF
     EARSGIAFEI VRTATWTESL EAAQARRCDI LPMAMETLDR LAYLNFSRPY FSVPMVLLGR
     VEAPFVDGLD ELDGRPVGVL RGHAAGELLR ARYPGLRIVE VDDELEGLRR VQRGELHGYV
     GSLMSVSHLL QEHGLADIKV LARVPGDVLL SVATRNDEPA LASIAQKLVD AVGDDERRQI
     EARWRAVRLE QRVDYALLWQ LGGGALLGLG LLFVWNRKLG ALNRRLEDAN AALERVALTD
     SLTGVGNRKF FDRHFGATMR WCQRHELVFM VAMIDVDHFK AINDNHGHQI GDDCLVALGA
     CLQAHLRRES DHVARFGGEE FVVFCALAAG EDAQAWLEAL RVKVEALRVA SPAGELRFTV
     SIGFADGVPG PAARAEDYLA RADQALYEAK RNGRNRCVRA SA
//