ID A0A2T4JH25_9RHOB Unreviewed; 450 AA.
AC A0A2T4JH25;
DT 18-JUL-2018, integrated into UniProtKB/TrEMBL.
DT 18-JUL-2018, sequence version 1.
DT 24-JAN-2024, entry version 20.
DE RecName: Full=Zinc metalloprotease {ECO:0000256|RuleBase:RU362031};
DE EC=3.4.24.- {ECO:0000256|RuleBase:RU362031};
GN Name=rseP {ECO:0000313|EMBL:PTE17087.1};
GN ORFNames=C5F46_10920 {ECO:0000313|EMBL:PTE17087.1};
OS Phaeovulum veldkampii DSM 11550.
OC Bacteria; Pseudomonadota; Alphaproteobacteria; Rhodobacterales;
OC Paracoccaceae; Phaeovulum.
OX NCBI_TaxID=1185920 {ECO:0000313|EMBL:PTE17087.1, ECO:0000313|Proteomes:UP000241899};
RN [1] {ECO:0000313|EMBL:PTE17087.1, ECO:0000313|Proteomes:UP000241899}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 11550 {ECO:0000313|EMBL:PTE17087.1,
RC ECO:0000313|Proteomes:UP000241899};
RA Meyer T.E., Miller S., Lodha T., Gandham S., Chintalapati S.,
RA Chintalapati V.R.;
RT "Rhodobacter veldkampii.";
RL Submitted (MAR-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- COFACTOR:
CC Name=Zn(2+); Xref=ChEBI:CHEBI:29105;
CC Evidence={ECO:0000256|ARBA:ARBA00001947,
CC ECO:0000256|RuleBase:RU362031};
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the peptidase M50B family.
CC {ECO:0000256|ARBA:ARBA00007931, ECO:0000256|RuleBase:RU362031}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PTE17087.1}.
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DR EMBL; PZKF01000024; PTE17087.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2T4JH25; -.
DR OrthoDB; 9782003at2; -.
DR Proteomes; UP000241899; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.
DR GO; GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
DR CDD; cd00989; PDZ_metalloprotease; 1.
DR CDD; cd06163; S2P-M50_PDZ_RseP-like; 1.
DR Gene3D; 2.30.42.10; -; 1.
DR InterPro; IPR001478; PDZ.
DR InterPro; IPR041489; PDZ_6.
DR InterPro; IPR036034; PDZ_sf.
DR InterPro; IPR004387; Pept_M50_Zn.
DR InterPro; IPR008915; Peptidase_M50.
DR NCBIfam; TIGR00054; RIP metalloprotease RseP; 1.
DR PANTHER; PTHR42837:SF2; MEMBRANE METALLOPROTEASE ARASP2, CHLOROPLASTIC-RELATED; 1.
DR PANTHER; PTHR42837; REGULATOR OF SIGMA-E PROTEASE RSEP; 1.
DR Pfam; PF17820; PDZ_6; 1.
DR Pfam; PF02163; Peptidase_M50; 1.
DR SMART; SM00228; PDZ; 1.
DR SUPFAM; SSF50156; PDZ domain-like; 2.
PE 3: Inferred from homology;
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000256|RuleBase:RU362031};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|RuleBase:RU362031};
KW Metal-binding {ECO:0000256|RuleBase:RU362031};
KW Metalloprotease {ECO:0000256|ARBA:ARBA00023049,
KW ECO:0000256|RuleBase:RU362031};
KW Protease {ECO:0000256|ARBA:ARBA00022670, ECO:0000313|EMBL:PTE17087.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000241899};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692,
KW ECO:0000256|RuleBase:RU362031};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|RuleBase:RU362031};
KW Zinc {ECO:0000256|ARBA:ARBA00022833, ECO:0000256|RuleBase:RU362031}.
FT TRANSMEM 12..30
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362031"
FT TRANSMEM 114..142
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362031"
FT TRANSMEM 379..401
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362031"
FT TRANSMEM 422..443
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362031"
FT DOMAIN 160..275
FT /note="PDZ"
FT /evidence="ECO:0000259|SMART:SM00228"
SQ SEQUENCE 450 AA; 47379 MW; 4DF0273134298F4F CRC64;
MDLIGLLPDF GNLLYTIAAF VVALSIIVTV HEFGHYIVGR WSGIRSEVFS IGFGPRLFSR
VDRHGTRWQV ALLPLGGYVK FLGDANAASA KADEAEMAAL SPEDRRHTMH GAPLWARAAT
VAAGPVFNFI LALAIFTGVF LYSGTATDRP EVGSLFDLPG GSGAVMVGDR ILAVEGMPTP
DYEALDQAMR SLPPAPLFDY LVERAGQQIT VPGPVLYPAR LAGIGAGSAA MDAGLKAGDV
LVRAEGKPIY GFVELQNAVG ASGGQPMTLE IWRPGMAADE TMTVTLTPRS TDLPLRDGGF
ETRFLMGANG NFFFAPQTRP TGLLEAAGDA VGEVRFIIVS SLSGLWNMIT GAISSCNLRG
PLGIAETSAA AASTGAGNFI WFIAVLSTAV GLLNLFPIPV LDGGHLVFHA WEAVTGKPPS
DRVLNALMTV GLALILMLMA FGLSNDLFCP
//
