ID   A0A2T4U8R3_9BACI        Unreviewed;       344 AA.
AC   A0A2T4U8R3;
DT   18-JUL-2018, integrated into UniProtKB/TrEMBL.
DT   18-JUL-2018, sequence version 1.
DT   24-JAN-2024, entry version 17.
DE   SubName: Full=Low-specificity L-threonine aldolase {ECO:0000313|EMBL:PTL39779.1};
GN   ORFNames=C6Y45_03785 {ECO:0000313|EMBL:PTL39779.1};
OS   Alkalicoccus saliphilus.
OC   Bacteria; Bacillota; Bacilli; Bacillales; Bacillaceae; Alkalicoccus.
OX   NCBI_TaxID=200989 {ECO:0000313|EMBL:PTL39779.1, ECO:0000313|Proteomes:UP000240509};
RN   [1] {ECO:0000313|EMBL:PTL39779.1, ECO:0000313|Proteomes:UP000240509}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=6AG {ECO:0000313|EMBL:PTL39779.1,
RC   ECO:0000313|Proteomes:UP000240509};
RA   Zhao B.;
RT   "Alkalicoccus saliphilus sp. nov., isolated from a mineral pool.";
RL   Submitted (MAR-2018) to the EMBL/GenBank/DDBJ databases.
CC   -!- COFACTOR:
CC       Name=pyridoxal 5'-phosphate; Xref=ChEBI:CHEBI:597326;
CC         Evidence={ECO:0000256|ARBA:ARBA00001933};
CC   -!- SIMILARITY: Belongs to the threonine aldolase family.
CC       {ECO:0000256|ARBA:ARBA00006966}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:PTL39779.1}.
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DR   EMBL; PZJJ01000004; PTL39779.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A2T4U8R3; -.
DR   OrthoDB; 9774495at2; -.
DR   Proteomes; UP000240509; Unassembled WGS sequence.
DR   GO; GO:0016829; F:lyase activity; IEA:InterPro.
DR   GO; GO:0006520; P:amino acid metabolic process; IEA:InterPro.
DR   CDD; cd06502; TA_like; 1.
DR   Gene3D; 3.90.1150.10; Aspartate Aminotransferase, domain 1; 1.
DR   Gene3D; 3.40.640.10; Type I PLP-dependent aspartate aminotransferase-like (Major domain); 1.
DR   InterPro; IPR001597; ArAA_b-elim_lyase/Thr_aldolase.
DR   InterPro; IPR023603; Low_specificity_L-TA-like.
DR   InterPro; IPR015424; PyrdxlP-dep_Trfase.
DR   InterPro; IPR015421; PyrdxlP-dep_Trfase_major.
DR   InterPro; IPR015422; PyrdxlP-dep_Trfase_small.
DR   NCBIfam; NF041359; GntG_guanitoxin; 1.
DR   PANTHER; PTHR48097:SF9; L-THREONINE ALDOLASE; 1.
DR   PANTHER; PTHR48097; L-THREONINE ALDOLASE-RELATED; 1.
DR   Pfam; PF01212; Beta_elim_lyase; 1.
DR   PIRSF; PIRSF017617; Thr_aldolase; 1.
DR   SUPFAM; SSF53383; PLP-dependent transferases; 1.
PE   3: Inferred from homology;
FT   DOMAIN          3..286
FT                   /note="Aromatic amino acid beta-eliminating lyase/threonine
FT                   aldolase"
FT                   /evidence="ECO:0000259|Pfam:PF01212"
FT   MOD_RES         199
FT                   /note="N6-(pyridoxal phosphate)lysine"
FT                   /evidence="ECO:0000256|PIRSR:PIRSR017617-1"
SQ   SEQUENCE   344 AA;  37440 MW;  DEC20222CE2240DF CRC64;
     MIDLRSDTVT KPDDMMRRLM SEADVGDDVF GEDPTVNELE NYAARLLGKE AALFTTSGTQ
     GNQAALLTHC RPGQEVIMDD EAHVFVYEGA AISAFAGLQS RTLPHQNGVI NIETLKAAIR
     PEDVHYPETG LIWLENTHNR GGGAVLPLDY LKQVKETADD YGLPVHMDGA RLFNAAEALQ
     VEASEIAAFA DSVQFCLSKG LGAPVGSVLA GSSSFIRTAR KKRKMLGGGM RQAGVIAAPG
     LYALQERRAR LKEDHLHARR LAEAIHEYTD LTIRHSVETN IIVADTDTSA RSAAEWVDLL
     AAEGTAIIQY KPKALRFTTN ADVSYEDIEE VVSILRGLPG KEEI
//