ID   A0A2T4Z7P2_9BACL        Unreviewed;       550 AA.
AC   A0A2T4Z7P2;
DT   18-JUL-2018, integrated into UniProtKB/TrEMBL.
DT   18-JUL-2018, sequence version 1.
DT   24-JAN-2024, entry version 13.
DE   SubName: Full=tRNA-specific A34 adenosine deaminase {ECO:0000313|EMBL:PTM57893.1};
GN   ORFNames=C8J48_0458 {ECO:0000313|EMBL:PTM57893.1};
OS   Desmospora activa DSM 45169.
OC   Bacteria; Bacillota; Bacilli; Bacillales; Thermoactinomycetaceae;
OC   Desmospora.
OX   NCBI_TaxID=1121389 {ECO:0000313|EMBL:PTM57893.1, ECO:0000313|Proteomes:UP000241639};
RN   [1] {ECO:0000313|EMBL:PTM57893.1, ECO:0000313|Proteomes:UP000241639}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 45169 {ECO:0000313|EMBL:PTM57893.1,
RC   ECO:0000313|Proteomes:UP000241639};
RA   Goeker M.;
RT   "Genomic Encyclopedia of Archaeal and Bacterial Type Strains, Phase II
RT   (KMG-II): from individual species to whole genera.";
RL   Submitted (APR-2018) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:PTM57893.1}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; PZZP01000001; PTM57893.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A2T4Z7P2; -.
DR   OrthoDB; 485723at2; -.
DR   Proteomes; UP000241639; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   GO; GO:0008251; F:tRNA-specific adenosine deaminase activity; IEA:InterPro.
DR   GO; GO:0002100; P:tRNA wobble adenosine to inosine editing; IEA:InterPro.
DR   InterPro; IPR016193; Cytidine_deaminase-like.
DR   InterPro; IPR028883; tRNA_aden_deaminase.
DR   Pfam; PF14437; MafB19-deam; 1.
DR   SUPFAM; SSF53927; Cytidine deaminase-like; 1.
PE   4: Predicted;
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000241639};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius};
KW   tRNA processing {ECO:0000256|ARBA:ARBA00022694}.
FT   TRANSMEM        20..41
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   REGION          64..106
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          375..394
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        71..90
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   550 AA;  58616 MW;  6D7F9FDEDD82E8D4 CRC64;
     MNVFKRFCNT LFSRKGSSTI EYVIVMSAGA ILASALLSAL YSEAIKKPMV AVIENHIACL
     NEEPSCNRGG SRGGEGTQVS EASGSGGPSD SPEQEPPDED KGGWSGLLQK GKEFASDAWD
     GVTEPIADAW NGLQEYASDS IDNAKDRYQY WLDHEGGREK ILAADEFLSQ SAVYREFRGD
     IIEGNWLRYS IRMLNYMSGA GITTALISEL TGFDLIKWGV DNPGATLTMA AGVGMLFFPP
     TTLLGIGVLS GGGISGAITA FSGGSADEVA DAMFIGGLTG LIGGGVAGGV ARAGLRYIGQ
     RAAQWVGASI GSSSESLADN FLRGEKLNWK NAAAAGLFAF GSVVGLNAAK NSIPTFGITP
     KSNQVANQAS KNADPNVVAG VKKPPVTPSQ FDNVRKDMGL PARIGDDDPY TTSVLRIDGH
     EYWGKNGKWV TKGKTSNYTD KAHYDKVRKE LGTSAEVPGH AEGVAFNKAY QVRKNTGTKG
     GNAVLYVDKI PCVMCKPGIA TLMRSAKVDH LDLHYLQDGK MHHVQYVRNP DTDAVYNPFS
     GKWTKPSKKK
//