ID A0A2T5JG19_9SPHI Unreviewed; 559 AA.
AC A0A2T5JG19;
DT 18-JUL-2018, integrated into UniProtKB/TrEMBL.
DT 18-JUL-2018, sequence version 1.
DT 24-JAN-2024, entry version 15.
DE RecName: Full=DNA-directed DNA polymerase {ECO:0000256|ARBA:ARBA00012417};
DE EC=2.7.7.7 {ECO:0000256|ARBA:ARBA00012417};
GN ORFNames=C8P68_101589 {ECO:0000313|EMBL:PTR01355.1};
OS Mucilaginibacter yixingensis.
OC Bacteria; Bacteroidota; Sphingobacteriia; Sphingobacteriales;
OC Sphingobacteriaceae; Mucilaginibacter.
OX NCBI_TaxID=1295612 {ECO:0000313|EMBL:PTR01355.1, ECO:0000313|Proteomes:UP000244168};
RN [1] {ECO:0000313|EMBL:PTR01355.1, ECO:0000313|Proteomes:UP000244168}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 26809 {ECO:0000313|EMBL:PTR01355.1,
RC ECO:0000313|Proteomes:UP000244168};
RA Goeker M.;
RT "Genomic Encyclopedia of Archaeal and Bacterial Type Strains, Phase II
RT (KMG-II): from individual species to whole genera.";
RL Submitted (APR-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=a 2'-deoxyribonucleoside 5'-triphosphate + DNA(n) =
CC diphosphate + DNA(n+1); Xref=Rhea:RHEA:22508, Rhea:RHEA-COMP:17339,
CC Rhea:RHEA-COMP:17340, ChEBI:CHEBI:33019, ChEBI:CHEBI:61560,
CC ChEBI:CHEBI:173112; EC=2.7.7.7;
CC Evidence={ECO:0000256|ARBA:ARBA00024632};
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PTR01355.1}.
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DR EMBL; QAOQ01000001; PTR01355.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2T5JG19; -.
DR OrthoDB; 9808747at2; -.
DR Proteomes; UP000244168; Unassembled WGS sequence.
DR GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR GO; GO:0003887; F:DNA-directed DNA polymerase activity; IEA:UniProtKB-KW.
DR GO; GO:0006281; P:DNA repair; IEA:UniProtKB-KW.
DR CDD; cd07436; PHP_PolX; 1.
DR Gene3D; 1.10.150.20; 5' to 3' exonuclease, C-terminal subdomain; 1.
DR Gene3D; 3.30.460.10; Beta Polymerase, domain 2; 1.
DR Gene3D; 1.10.150.110; DNA polymerase beta, N-terminal domain-like; 1.
DR Gene3D; 3.20.20.140; Metal-dependent hydrolases; 1.
DR InterPro; IPR002054; DNA-dir_DNA_pol_X.
DR InterPro; IPR010996; DNA_pol_b-like_N.
DR InterPro; IPR027421; DNA_pol_lamdba_lyase_dom_sf.
DR InterPro; IPR002008; DNA_pol_X_beta-like.
DR InterPro; IPR043519; NT_sf.
DR InterPro; IPR003141; Pol/His_phosphatase_N.
DR InterPro; IPR016195; Pol/histidinol_Pase-like.
DR InterPro; IPR022311; PolX-like.
DR InterPro; IPR047967; PolX_PHP.
DR PANTHER; PTHR36928; PHOSPHATASE YCDX-RELATED; 1.
DR PANTHER; PTHR36928:SF1; PHOSPHATASE YCDX-RELATED; 1.
DR Pfam; PF14520; HHH_5; 1.
DR Pfam; PF14716; HHH_8; 1.
DR PIRSF; PIRSF005047; UCP005047_YshC; 1.
DR PRINTS; PR00870; DNAPOLXBETA.
DR SMART; SM00481; POLIIIAc; 1.
DR SMART; SM00483; POLXc; 1.
DR SUPFAM; SSF47802; DNA polymerase beta, N-terminal domain-like; 1.
DR SUPFAM; SSF81301; Nucleotidyltransferase; 1.
DR SUPFAM; SSF89550; PHP domain-like; 1.
PE 4: Predicted;
KW DNA damage {ECO:0000256|ARBA:ARBA00022763};
KW DNA repair {ECO:0000256|ARBA:ARBA00023204};
KW DNA-directed DNA polymerase {ECO:0000256|ARBA:ARBA00022932};
KW Nucleotidyltransferase {ECO:0000256|ARBA:ARBA00022932};
KW Reference proteome {ECO:0000313|Proteomes:UP000244168};
KW Transferase {ECO:0000256|ARBA:ARBA00022932}.
FT DOMAIN 3..297
FT /note="DNA-directed DNA polymerase X"
FT /evidence="ECO:0000259|SMART:SM00483"
FT DOMAIN 321..401
FT /note="Polymerase/histidinol phosphatase N-terminal"
FT /evidence="ECO:0000259|SMART:SM00481"
SQ SEQUENCE 559 AA; 62839 MW; 3EA192A1F1F2D6A7 CRC64;
MENKTISRTL RLFSQLMELH EVNQFKIRSV ANAAFKVDKL PFKLAGKTTA EMEKIDGVGK
SLAGKITELL ETGAIAEMQD LRHNTPEGVI EMLHIKGIGP KKIGIIWHEL GIETIGELYY
ACNENRLIEA KGFGLKTQEE IAKAIDFRMA GNGKFLYAQI EDQAGVVIQL IRDTLPGALV
EFAGDYRRGC EVISELSVVI GSRDPDIAMQ ALQQLDVIKN INVDHHHING ELDSGLMIDL
ICVSKADYFK TLFLQTGNDQ HVDAILERIA GPLDSPTSEQ IIYQKAGLEY LAPELREGDA
WLEKAEQNTL PHLITRFDLK GTLHNHSTWS DGVNTLEEMA LYCRDEMKLE YLGISDHSKT
AVYAKGLSIE RVLQQHEEID HLNKKLENFH IFKGIESDIL GDGALDYPDE ILARFDFIVA
SVHSNLKMSE EKATARLIKA IENPYTTMLG HPTGRLLLSR AGYPIDYKKV IDACAANNVV
IEVNSNPLRL DLDWRWHQYA LDKGVWLSIN PDAHRNEGFH DMQFGVLVAR KGGLSKERCL
NAQSLADIKN FFEQQKAKR
//
