ID   A0A2T5LP91_9EURO        Unreviewed;       566 AA.
AC   A0A2T5LP91;
DT   18-JUL-2018, integrated into UniProtKB/TrEMBL.
DT   18-JUL-2018, sequence version 1.
DT   24-JAN-2024, entry version 12.
DE   RecName: Full=Adenosine deaminase domain-containing protein {ECO:0000259|Pfam:PF00962};
GN   ORFNames=P175DRAFT_0485159 {ECO:0000313|EMBL:PTU18095.1};
OS   Aspergillus ochraceoroseus IBT 24754.
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC   Eurotiomycetidae; Eurotiales; Aspergillaceae; Aspergillus;
OC   Aspergillus subgen. Nidulantes.
OX   NCBI_TaxID=1392256 {ECO:0000313|EMBL:PTU18095.1, ECO:0000313|Proteomes:UP000244073};
RN   [1] {ECO:0000313|EMBL:PTU18095.1, ECO:0000313|Proteomes:UP000244073}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=IBT 24754 {ECO:0000313|EMBL:PTU18095.1,
RC   ECO:0000313|Proteomes:UP000244073};
RX   PubMed=29317534; DOI=10.1073/pnas.1715954115;
RA   Kaerboelling I., Vesth T.C., Frisvad J.C., Nybo J.L., Theobald S., Kuo A.,
RA   Bowyer P., Matsuda Y., Mondo S., Lyhne E.K., Kogle M.E., Clum A.,
RA   Lipzen A., Salamov A., Ngan C.Y., Daum C., Chiniquy J., Barry K.,
RA   LaButti K., Haridas S., Simmons B.A., Magnuson J.K., Mortensen U.H.,
RA   Larsen T.O., Grigoriev I.V., Baker S.E., Andersen M.R.;
RT   "Linking secondary metabolites to gene clusters through genome sequencing
RT   of six diverse Aspergillus species.";
RL   Proc. Natl. Acad. Sci. U.S.A. 115:E753-E761(2018).
CC   -!- COFACTOR:
CC       Name=Zn(2+); Xref=ChEBI:CHEBI:29105;
CC         Evidence={ECO:0000256|ARBA:ARBA00001947};
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:PTU18095.1}.
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DR   EMBL; MSFN02000008; PTU18095.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A2T5LP91; -.
DR   VEuPathDB; FungiDB:P175DRAFT_0485159; -.
DR   OrthoDB; 4403at2759; -.
DR   Proteomes; UP000244073; Unassembled WGS sequence.
DR   GO; GO:0019239; F:deaminase activity; IEA:InterPro.
DR   Gene3D; 3.20.20.140; Metal-dependent hydrolases; 1.
DR   InterPro; IPR001365; A_deaminase_dom.
DR   InterPro; IPR006330; Ado/ade_deaminase.
DR   InterPro; IPR032466; Metal_Hydrolase.
DR   PANTHER; PTHR11409; ADENOSINE DEAMINASE; 1.
DR   PANTHER; PTHR11409:SF39; ADENOSINE DEAMINASE 2; 1.
DR   Pfam; PF00962; A_deaminase; 1.
DR   SUPFAM; SSF51556; Metallo-dependent hydrolases; 1.
PE   4: Predicted;
FT   DOMAIN          300..522
FT                   /note="Adenosine deaminase"
FT                   /evidence="ECO:0000259|Pfam:PF00962"
SQ   SEQUENCE   566 AA;  64136 MW;  1BAE991ED15D50A0 CRC64;
     MDPDNRLWEI EEGVPQLLDP FIQKFLAGRR SLIQEEKSQQ HDSNLCKALP EVAIRARKIV
     SRICSATRLE HGGIPHPSLM SDPDRERLES SDLWKIVRNL PKGSLLYGHL PVMIDIDFLI
     DQALATPGIY ISAPNPLITH HDFENATFFF HYMPAHQAEV EGSKDKPELS LWSDSYEPSA
     SLDLQTAAAL FPHGGQIGFR DWLKRRCAVS SENHPCGRRT SPISNLFNHY LPIVSPLFHH
     EPILRVCLRR IFSQLVADKI NYVEFRLAFD FQYTREGAEK PEADYFAWFH IFQEEISLFQ
     SLDEGKNFYG ARIIWAAPRN LSNKDIGESM KECIIMKKRF PALICGFDLL GQESTERPLH
     NLLPILFWFR GRCAEETVNI PFIFSAGQSM GAGDDADGNL FDAVLLSSRR ISQGLSLYTH
     PLLIDIIKKK NILIECSPTS NKGFGFTNSF QAHPIPALLS REVSVALCND SPGIFGNGEN
     GLSSEFWQAL LAFQNMGLTG LAMLVENSIR WSCYEDQTQS EWGSDIQEGI LGEGEKAARL
     HAFYAEFESF CQWVVREYGE KYPVEV
//