ID A0A2T5LRM9_9EURO Unreviewed; 2137 AA.
AC A0A2T5LRM9;
DT 18-JUL-2018, integrated into UniProtKB/TrEMBL.
DT 18-JUL-2018, sequence version 1.
DT 27-MAR-2024, entry version 19.
DE RecName: Full=CCHC-type domain-containing protein {ECO:0000259|PROSITE:PS50158};
GN ORFNames=P175DRAFT_0442009 {ECO:0000313|EMBL:PTU18943.1};
OS Aspergillus ochraceoroseus IBT 24754.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Eurotiales; Aspergillaceae; Aspergillus;
OC Aspergillus subgen. Nidulantes.
OX NCBI_TaxID=1392256 {ECO:0000313|EMBL:PTU18943.1, ECO:0000313|Proteomes:UP000244073};
RN [1] {ECO:0000313|EMBL:PTU18943.1, ECO:0000313|Proteomes:UP000244073}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=IBT 24754 {ECO:0000313|EMBL:PTU18943.1,
RC ECO:0000313|Proteomes:UP000244073};
RX PubMed=29317534; DOI=10.1073/pnas.1715954115;
RA Kaerboelling I., Vesth T.C., Frisvad J.C., Nybo J.L., Theobald S., Kuo A.,
RA Bowyer P., Matsuda Y., Mondo S., Lyhne E.K., Kogle M.E., Clum A.,
RA Lipzen A., Salamov A., Ngan C.Y., Daum C., Chiniquy J., Barry K.,
RA LaButti K., Haridas S., Simmons B.A., Magnuson J.K., Mortensen U.H.,
RA Larsen T.O., Grigoriev I.V., Baker S.E., Andersen M.R.;
RT "Linking secondary metabolites to gene clusters through genome sequencing
RT of six diverse Aspergillus species.";
RL Proc. Natl. Acad. Sci. U.S.A. 115:E753-E761(2018).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PTU18943.1}.
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DR EMBL; MSFN02000007; PTU18943.1; -; Genomic_DNA.
DR VEuPathDB; FungiDB:P175DRAFT_0442009; -.
DR OrthoDB; 170190at2759; -.
DR Proteomes; UP000244073; Unassembled WGS sequence.
DR GO; GO:0004386; F:helicase activity; IEA:InterPro.
DR GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR CDD; cd18042; DEXXQc_SETX; 1.
DR CDD; cd18808; SF1_C_Upf1; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR Gene3D; 4.10.60.10; Zinc finger, CCHC-type; 1.
DR InterPro; IPR045055; DNA2/NAM7-like.
DR InterPro; IPR041679; DNA2/NAM7-like_C.
DR InterPro; IPR041677; DNA2/NAM7_AAA_11.
DR InterPro; IPR024481; Helicase_Sen1_N.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR047187; SF1_C_Upf1.
DR InterPro; IPR001878; Znf_CCHC.
DR InterPro; IPR036875; Znf_CCHC_sf.
DR PANTHER; PTHR10887; DNA2/NAM7 HELICASE FAMILY; 1.
DR PANTHER; PTHR10887:SF525; HELICASE SENATAXIN-RELATED; 1.
DR Pfam; PF13086; AAA_11; 1.
DR Pfam; PF13087; AAA_12; 1.
DR Pfam; PF12726; SEN1_N; 1.
DR SMART; SM00343; ZnF_C2HC; 3.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF57756; Retrovirus zinc finger-like domains; 1.
DR PROSITE; PS50158; ZF_CCHC; 2.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Metal-binding {ECO:0000256|PROSITE-ProRule:PRU00047};
KW Zinc {ECO:0000256|PROSITE-ProRule:PRU00047};
KW Zinc-finger {ECO:0000256|PROSITE-ProRule:PRU00047}.
FT DOMAIN 1921..1934
FT /note="CCHC-type"
FT /evidence="ECO:0000259|PROSITE:PS50158"
FT DOMAIN 1938..1954
FT /note="CCHC-type"
FT /evidence="ECO:0000259|PROSITE:PS50158"
FT REGION 930..1039
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1846..1886
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1963..2137
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 1473..1500
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 949..973
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1846..1872
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1963..1990
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2008..2043
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2087..2111
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 2137 AA; 238745 MW; 095DB93E4ED8E6C9 CRC64;
MEFMDIVAEL QALPNDVHIL CPRQHDDDHA RYDDETEVDE SGKSVAELVL EANTRREKFL
SCMRILAFNQ EEVEELQNWI WRKIDDALEK CDLCIKQYYM GKIWLMDQLK ENYDEEDIEK
FSRMLDEWDI KRITKNLTTA TTKLREVPAE QIGLHVLDRA SLLSIFETLS CDAMLRNDSL
LKEYFDEPFQ LIQTKRTLKV SDYIPAVSRF LFDPNQSRSF WAIHSWMRYP RPPTTAEFDW
AIKEGLLAAL RTASQQPIQV AVIQRLWRGM QIVVKRLDKD QITHNLRALE IDPCRLSVDH
LAIQSPGLRF TLNTIQTFLE KAPGDFWDAM QTISPQAIVE VVFYNPQVDA FLTQATDGEP
YEKSAMKDIL SWVSPFMSSL KGAHQPTACR SLVYQLLDRL QDARFPNLAR YHCFHVGLVS
LLHTLRSFTD HEASRGSVAR VVLSETLGVV SEHINKILKP PQFAVEQGRQ REIKSLCMDV
IRNTLALECQ SLKSDYEVIL RQNSLQHGVS TYSSTIWDAV VQHLHEDDLA LSTSALLGIL
PLVGLEKFPT KGESSPEKTH FNSIYGHLTH LSCQIIERLA DFKPDHLDEL FKSQDTGSAL
ISALFAADHN TYQAAVDLIK NVSGQSARRD AISHLLESFF TTTMYGLSWS FRRISNMKTF
ASAPRMLHTG TDIVDILCDS QTGMLRTRKL ADRREILSLQ KLWEYLWQAL TTIFDETESW
HLRGNDKAVM LEFCRDSIQF ADLLFSQYGV FLSAVVDADP NQESSARENF IKPPTATMSG
MVKWLRLKDE YLATTLVGLV AKILRRLGEL SVTTVKEDAL NFIEGVAVKS TIKTIITPRE
KAELVRALEA YYKKPVVTAS TASLKKQSMI TAFAKPAEPS ASPSPSRTAD EFEEADLSDD
VLLQLSRSVE LNKERLAAEA KKKAERAAKA LPVIPKPAPA PPKSNLSVQA FREKRERERE
AKKKRDLAEL ARLKRGAPPH GVAEQTAHQG SAIAGIGIKG KDHTPAESMM VSSGSESESE
SEDELDKELF GPKTGSKPDA VKAYEESKRM SLRQQGPVKK IKQVRSAKDM RARLAPDLSS
LHRTILAWDF FAAGDLPPNS GRTDYSLVSN TFRDPIEYQR TFEPLLILEA WQGFRSSKEE
GSFKPFEVKV ATRLSVDSFV EVSTVMPALE VKDYGLGEAD IVLLSKGNSP ATDSSAPHCL
ARVSGINKKK GTVEVSYRVN PGIPFINSLG PGATIWGAKI TSLTPLEREY GALMALQYYD
LCEEVIKAKP SPILNYSDAS LKLVADNYNV NPAQAKAIKS ALDNDAFTLI QGPPGSGKTK
TIVALVGALL SGVLGEQGVS ISRPSATSST RGPARTTTSK KLLVCAPSNA AVDELVMRFK
DGVKTITGRH EKLSVIRLGR TDAINTNVLD VTLDELVNAR LNRTSRREGG EVDLQKIYME
HKAADTAFKE TRSKIDQCRA QGLPVPLELE REFDLLKKKK TQLSQQIDNA RDKNHSAARD
ADLNRRRIQQ EIIDGAHVIC ATLSGSGHEM FQNLSIEFET VVIDEAAQSI ELSALIPLKY
GCSKCILVGD PKQLPPTVLS KVASKFQYEQ SLFVRMQANH PRDVHLLDTQ YRMHPEISVF
PSTAFYDGKL QDGPNMARLR ARPWHQSELL TPYRFFDVQG MHQSATKGHS LINIAELKVA
MQLYERLVTD FRDYNFSGKI GIITPYKGQL RELKNHFAAK YGNAIFSMID FNTTDAFQGR
ESEVIIFSCV RASNKGIGFL SDIRRMNVGL TRAKSSLWVL GNSQSLIQGE FWNSLIKDAR
RRNVYTEGEI LKVLQKPQFT GYKNIDMVDA DASESAVPSR AASAASISRP SSASLDNLPS
QSPFSATASA KGTPPASLPD GPSGGPNGLD ETRMCGYCGS FTHMTHNCDN EEVKEMAKGT
CYRCGEPGHT RFACAAERCT ECGQFGHASN SCRSTKVLPK HEKNRIAREE YNHARNQKQR
TEKQRLKQLG GHDPKVPVIQ VTTEQPANDN RKSERPRPDH AAGSSKRKRT DSPVADASKS
ARPRKFEQGA PPTGPKNQRH KIDANIPSNT ENLVKPSRDG PAYTPLSGKP LSSTPSGPDP
TRQAPRQPQQ RPSNGTRPPP PMRKRKEVDP FIRPKRR
//
