ID A0A2T5MCN0_9GAMM Unreviewed; 632 AA.
AC A0A2T5MCN0;
DT 18-JUL-2018, integrated into UniProtKB/TrEMBL.
DT 18-JUL-2018, sequence version 1.
DT 27-MAR-2024, entry version 18.
DE SubName: Full=Propionyl-CoA synthetase {ECO:0000313|EMBL:PTU30336.1};
DE EC=6.2.1.17 {ECO:0000313|EMBL:PTU30336.1};
GN Name=prpE {ECO:0000313|EMBL:PTU30336.1};
GN Synonyms=yahU {ECO:0000313|EMBL:PTU30336.1};
GN ORFNames=CJD38_15435 {ECO:0000313|EMBL:PTU30336.1};
OS Stenotrophobium rhamnosiphilum.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Nevskiales; Nevskiaceae;
OC Stenotrophobium.
OX NCBI_TaxID=2029166 {ECO:0000313|EMBL:PTU30336.1, ECO:0000313|Proteomes:UP000244248};
RN [1] {ECO:0000313|EMBL:PTU30336.1, ECO:0000313|Proteomes:UP000244248}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=GT1R17 {ECO:0000313|EMBL:PTU30336.1,
RC ECO:0000313|Proteomes:UP000244248};
RA Liu Q., Xin Y.-H.;
RT "Novel species isolated from glacier.";
RL Submitted (APR-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the ATP-dependent AMP-binding enzyme family.
CC {ECO:0000256|ARBA:ARBA00006432}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PTU30336.1}.
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DR EMBL; QANS01000006; PTU30336.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2T5MCN0; -.
DR OrthoDB; 9803968at2; -.
DR Proteomes; UP000244248; Unassembled WGS sequence.
DR GO; GO:0050218; F:propionate-CoA ligase activity; IEA:UniProtKB-EC.
DR CDD; cd05967; PrpE; 1.
DR Gene3D; 3.30.300.30; -; 1.
DR Gene3D; 3.40.50.12780; N-terminal domain of ligase-like; 1.
DR InterPro; IPR032387; ACAS_N.
DR InterPro; IPR025110; AMP-bd_C.
DR InterPro; IPR045851; AMP-bd_C_sf.
DR InterPro; IPR020845; AMP-binding_CS.
DR InterPro; IPR000873; AMP-dep_Synth/Lig_com.
DR InterPro; IPR042099; ANL_N_sf.
DR PANTHER; PTHR43347; ACYL-COA SYNTHETASE; 1.
DR PANTHER; PTHR43347:SF3; ACYL-COA SYNTHETASE SHORT-CHAIN FAMILY MEMBER 3, MITOCHONDRIAL; 1.
DR Pfam; PF16177; ACAS_N; 1.
DR Pfam; PF00501; AMP-binding; 1.
DR Pfam; PF13193; AMP-binding_C; 1.
DR SUPFAM; SSF56801; Acetyl-CoA synthetase-like; 1.
DR PROSITE; PS00455; AMP_BINDING; 1.
PE 3: Inferred from homology;
KW Ligase {ECO:0000313|EMBL:PTU30336.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000244248}.
FT DOMAIN 6..60
FT /note="Acetyl-coenzyme A synthetase N-terminal"
FT /evidence="ECO:0000259|Pfam:PF16177"
FT DOMAIN 67..448
FT /note="AMP-dependent synthetase/ligase"
FT /evidence="ECO:0000259|Pfam:PF00501"
FT DOMAIN 513..591
FT /note="AMP-binding enzyme C-terminal"
FT /evidence="ECO:0000259|Pfam:PF13193"
SQ SEQUENCE 632 AA; 69029 MW; ACF383CD923FCC99 CRC64;
MSASKYAEQY QRSLSEPEIF WAEQAAKLRW HKPWSKVLDD SKAPFYRWFA GAEFNTCYNA
LDRHVEEGRA DQVAITYDSP LTNSLKKFTY RELRDEVALF AGALRANGVK RGDLVVIYMP
MVPEAAVAML ACARIGAVHS VVFGGFAAPE LAKRIDAAKP VLLVSATCGI EPGRVIDYKP
LLDQAIELAE HKVTRTIILQ RPQREAALIA GRDVDWQEAV EAAQPADCVP VASTDPLYVL
YTSGTTGKPK GVVRDHGGHA VALMYSMKTV FDTNPGDVFW AASDVGWVVG HSYIVYGPLL
QGCTTIFYEG KPVGTPDAGA FWRVISQHGV KTFFTAPTAF RAIKKEDPEG KLIGQYDLSK
FKTLYLAGER CDPDTILWAQ DKLKVPVIDN WWQTELGWSA IANCQGLELM PVKPGSAAVP
VPGFEFAVLD NAGTPVKDDD IGNVVIKLPL PPGTLSTMWQ NDQGYHDNYL SRYPGYYLTG
DAGYRDTDGY LWIMSRIDDI INVAGHRLST GAMEEVLSSH PAVAECAVIG VADALKGQLP
VGLVVLKAGV TKSSEEIVRE LVERVRAQIG AVAAFKQATV IARLPKTRSG KVLRSTMRSI
ADSQPHTVPA TIDDPKSLEE IATALQALGY AK
//
