ID A0A2T5PFL4_9PSED Unreviewed; 347 AA.
AC A0A2T5PFL4;
DT 18-JUL-2018, integrated into UniProtKB/TrEMBL.
DT 18-JUL-2018, sequence version 1.
DT 27-MAR-2024, entry version 19.
DE RecName: Full=lipopolysaccharide heptosyltransferase II {ECO:0000256|ARBA:ARBA00044042};
DE EC=2.4.99.24 {ECO:0000256|ARBA:ARBA00044042};
GN Name=waaF {ECO:0000313|EMBL:PTU76502.1};
GN ORFNames=DBO85_02370 {ECO:0000313|EMBL:PTU76502.1};
OS Pseudomonas mangrovi.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Pseudomonadales;
OC Pseudomonadaceae; Pseudomonas.
OX NCBI_TaxID=2161748 {ECO:0000313|EMBL:PTU76502.1, ECO:0000313|Proteomes:UP000244064};
RN [1] {ECO:0000313|EMBL:PTU76502.1, ECO:0000313|Proteomes:UP000244064}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=TC-11 {ECO:0000313|EMBL:PTU76502.1,
RC ECO:0000313|Proteomes:UP000244064};
RA Chen C.;
RT "Pseudomonas sp. nov., isolated from mangrove soil.";
RL Submitted (APR-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ADP-L-glycero-beta-D-manno-heptose + an L-alpha-D-Hep-(1->5)-
CC [alpha-Kdo-(2->4)]-alpha-Kdo-(2->6)-lipid A = ADP + an L-alpha-D-Hep-
CC (1->3)-L-alpha-D-Hep-(1->5)-[alpha-Kdo-(2->4)]-alpha-Kdo-(2->6)-lipid
CC A + H(+); Xref=Rhea:RHEA:74071, ChEBI:CHEBI:15378, ChEBI:CHEBI:61506,
CC ChEBI:CHEBI:193068, ChEBI:CHEBI:193069, ChEBI:CHEBI:456216;
CC EC=2.4.99.24; Evidence={ECO:0000256|ARBA:ARBA00043830};
CC -!- SIMILARITY: Belongs to the glycosyltransferase 9 family.
CC {ECO:0000256|ARBA:ARBA00043995}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PTU76502.1}.
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DR EMBL; QASN01000002; PTU76502.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2T5PFL4; -.
DR OrthoDB; 9797795at2; -.
DR Proteomes; UP000244064; Unassembled WGS sequence.
DR GO; GO:0016757; F:glycosyltransferase activity; IEA:InterPro.
DR GO; GO:0009103; P:lipopolysaccharide biosynthetic process; IEA:InterPro.
DR CDD; cd03789; GT9_LPS_heptosyltransferase; 1.
DR Gene3D; 3.40.50.2000; Glycogen Phosphorylase B; 2.
DR InterPro; IPR002201; Glyco_trans_9.
DR InterPro; IPR011910; RfaF.
DR NCBIfam; TIGR02195; heptsyl_trn_II; 1.
DR PANTHER; PTHR30160:SF7; ADP-HEPTOSE--LPS HEPTOSYLTRANSFERASE 2; 1.
DR PANTHER; PTHR30160; TETRAACYLDISACCHARIDE 4'-KINASE-RELATED; 1.
DR Pfam; PF01075; Glyco_transf_9; 1.
DR SUPFAM; SSF53756; UDP-Glycosyltransferase/glycogen phosphorylase; 1.
PE 3: Inferred from homology;
KW Glycosyltransferase {ECO:0000256|ARBA:ARBA00022676};
KW Reference proteome {ECO:0000313|Proteomes:UP000244064};
KW Transferase {ECO:0000256|ARBA:ARBA00022679, ECO:0000313|EMBL:PTU76502.1}.
SQ SEQUENCE 347 AA; 37940 MW; 43D5FD94ACD2E4DA CRC64;
MNILIIGPSW VGDMVMAQTL FSCLRQRHPG CAIDVLAPEW SRPILERMPE VRAALSFPLG
HGALELATRR RIGKSLAGQY DQAILLPNSL KSALVPFFAG IPVRTGWKGE MRYGLLNDIR
TLDKARYPLM IERFMALAFA PGAELPQPYP RPQLQIDPAS RAAALARFSL ALDRPLLALC
PGAEFGEAKR WPAEHYARVA EQKIRDGWQV WLFGSKSDHP VGEEIRAALI PGLREEVCNL
AGETSLAEAI DLLSCSDAVV SNDSGLMHVA AALQRPLVSV YGSTSPGFTP PLAEQVEVVR
LGLDCSPCFD RTCRFGHYNC LRDLSPALVL EALQRLVGDP LAEPGSL
//
