ID   A0A2T6BGN1_9BACL        Unreviewed;       474 AA.
AC   A0A2T6BGN1;
DT   18-JUL-2018, integrated into UniProtKB/TrEMBL.
DT   18-JUL-2018, sequence version 1.
DT   27-MAR-2024, entry version 13.
DE   SubName: Full=Arginine/lysine/ornithine decarboxylase {ECO:0000313|EMBL:PTX55210.1};
GN   ORFNames=C8P63_1204 {ECO:0000313|EMBL:PTX55210.1};
OS   Melghirimyces profundicolus.
OC   Bacteria; Bacillota; Bacilli; Bacillales; Thermoactinomycetaceae;
OC   Melghirimyces.
OX   NCBI_TaxID=1242148 {ECO:0000313|EMBL:PTX55210.1, ECO:0000313|Proteomes:UP000244240};
RN   [1] {ECO:0000313|EMBL:PTX55210.1, ECO:0000313|Proteomes:UP000244240}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 45787 {ECO:0000313|EMBL:PTX55210.1,
RC   ECO:0000313|Proteomes:UP000244240};
RA   Goeker M.;
RT   "Genomic Encyclopedia of Archaeal and Bacterial Type Strains, Phase II
RT   (KMG-II): from individual species to whole genera.";
RL   Submitted (APR-2018) to the EMBL/GenBank/DDBJ databases.
CC   -!- COFACTOR:
CC       Name=pyridoxal 5'-phosphate; Xref=ChEBI:CHEBI:597326;
CC         Evidence={ECO:0000256|ARBA:ARBA00001933};
CC   -!- SIMILARITY: Belongs to the Orn/Lys/Arg decarboxylase class-I family.
CC       {ECO:0000256|ARBA:ARBA00010671}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:PTX55210.1}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; QBKR01000020; PTX55210.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A2T6BGN1; -.
DR   OrthoDB; 9815233at2; -.
DR   Proteomes; UP000244240; Unassembled WGS sequence.
DR   GO; GO:0003824; F:catalytic activity; IEA:InterPro.
DR   CDD; cd00615; Orn_deC_like; 1.
DR   Gene3D; 3.90.100.10; Orn/Lys/Arg decarboxylase, C-terminal domain; 1.
DR   Gene3D; 3.40.640.10; Type I PLP-dependent aspartate aminotransferase-like (Major domain); 1.
DR   InterPro; IPR000310; Orn/Lys/Arg_deCO2ase_major_dom.
DR   InterPro; IPR008286; Prn/Lys/Arg_de-COase_C.
DR   InterPro; IPR036633; Prn/Lys/Arg_de-COase_C_sf.
DR   InterPro; IPR015424; PyrdxlP-dep_Trfase.
DR   InterPro; IPR015421; PyrdxlP-dep_Trfase_major.
DR   PANTHER; PTHR43277; ARGININE DECARBOXYLASE; 1.
DR   PANTHER; PTHR43277:SF3; LYSINE DECARBOXYLASE; 1.
DR   Pfam; PF01276; OKR_DC_1; 1.
DR   Pfam; PF03711; OKR_DC_1_C; 1.
DR   SUPFAM; SSF55904; Ornithine decarboxylase C-terminal domain; 1.
DR   SUPFAM; SSF53383; PLP-dependent transferases; 1.
PE   3: Inferred from homology;
KW   Pyridoxal phosphate {ECO:0000256|ARBA:ARBA00022898};
KW   Reference proteome {ECO:0000313|Proteomes:UP000244240}.
FT   DOMAIN          10..303
FT                   /note="Orn/Lys/Arg decarboxylases family 1 pyridoxal-P
FT                   attachment site"
FT                   /evidence="ECO:0000259|Pfam:PF01276"
FT   DOMAIN          393..447
FT                   /note="Orn/Lys/Arg decarboxylase C-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF03711"
SQ   SEQUENCE   474 AA;  52772 MW;  66B5A720D6EAF60E CRC64;
     MEPKTQQKAP LYDALMRHRE KSRGNFHVPG HKQGRAFDAE ARVLYRELLT LDLTEIGDLD
     DLHQAEGVIR EAQELAAEAF GADRTFFLVG GSTAGNLAMI LGSCRPGERL LVHRSSHQSV
     FHGCMLAGVR PVFIKGRGAG PLGGSLEPGD LDRALDVYAD VKGVVVTSPD YFGRTQPLSE
     LAAVCHRHGV PLLVDEAHGA HFGFHPDLPA PALSQGADGV VQSTHKMLPA MTMSSMLHLR
     GHRLDPERIR HGLKIIQSSS PSYPLMASLD LARRFMVTRG EEELGRVLKR IRLFREQISR
     LVHLVEYRFP ESDPLKVCIG AHRPVTGYRL LRWLEDRKMY LEMADHEKVL AVFSPGTEWE
     EVDRLMEWLE GLDDEIPGME ECPPFPSPDI PVMRESEVSY EQLRTAEVET VPLQKAGGRL
     AARTVVSYPP GVPLLLPGER VRREQTEEIA RLIRQGGRVR GLASGFPVGV YVIK
//