ID   A0A2T6BSY3_9BACL        Unreviewed;       315 AA.
AC   A0A2T6BSY3;
DT   18-JUL-2018, integrated into UniProtKB/TrEMBL.
DT   18-JUL-2018, sequence version 1.
DT   27-MAR-2024, entry version 10.
DE   SubName: Full=Glyoxylase-like metal-dependent hydrolase (Beta-lactamase superfamily II) {ECO:0000313|EMBL:PTX59067.1};
GN   ORFNames=C8P63_11312 {ECO:0000313|EMBL:PTX59067.1};
OS   Melghirimyces profundicolus.
OC   Bacteria; Bacillota; Bacilli; Bacillales; Thermoactinomycetaceae;
OC   Melghirimyces.
OX   NCBI_TaxID=1242148 {ECO:0000313|EMBL:PTX59067.1, ECO:0000313|Proteomes:UP000244240};
RN   [1] {ECO:0000313|EMBL:PTX59067.1, ECO:0000313|Proteomes:UP000244240}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 45787 {ECO:0000313|EMBL:PTX59067.1,
RC   ECO:0000313|Proteomes:UP000244240};
RA   Goeker M.;
RT   "Genomic Encyclopedia of Archaeal and Bacterial Type Strains, Phase II
RT   (KMG-II): from individual species to whole genera.";
RL   Submitted (APR-2018) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:PTX59067.1}.
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DR   EMBL; QBKR01000013; PTX59067.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A2T6BSY3; -.
DR   OrthoDB; 9761531at2; -.
DR   Proteomes; UP000244240; Unassembled WGS sequence.
DR   GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR   CDD; cd07726; ST1585-like_MBL-fold; 1.
DR   Gene3D; 3.60.15.10; Ribonuclease Z/Hydroxyacylglutathione hydrolase-like; 1.
DR   InterPro; IPR001279; Metallo-B-lactamas.
DR   InterPro; IPR036866; RibonucZ/Hydroxyglut_hydro.
DR   InterPro; IPR037482; ST1585_MBL-fold.
DR   PANTHER; PTHR42951; METALLO-BETA-LACTAMASE DOMAIN-CONTAINING; 1.
DR   PANTHER; PTHR42951:SF26; METALLO-HYDROLASE YQJP-RELATED; 1.
DR   Pfam; PF00753; Lactamase_B; 1.
DR   SMART; SM00849; Lactamase_B; 1.
DR   SUPFAM; SSF56281; Metallo-hydrolase/oxidoreductase; 1.
PE   4: Predicted;
KW   Hydrolase {ECO:0000313|EMBL:PTX59067.1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000244240}.
FT   DOMAIN          26..230
FT                   /note="Metallo-beta-lactamase"
FT                   /evidence="ECO:0000259|SMART:SM00849"
SQ   SEQUENCE   315 AA;  35606 MW;  3CEA5A970B41961A CRC64;
     MEPIRLFDWG HRIRMIDGYD LNMPSRTGIY VLEEEELTLI ETGPSPSVPY ILKGLEELGH
     RPEDVRNVIV THIHLDHAGG AGLLLKSCPE ARVVVHPRGA RHLADPSRLI QGARMVYGDQ
     FDALFDPVLP IGEERILVRG DGEKLAIGPD RTLTFLDSPG HAAHHFTIHD PVSNGLFTGD
     TAGIHYAQTE EFGFRLYLPS TSPNQFDPDA MKASIERFRE RRPERIFFGH FGMSEEPAAV
     FEQVKEELEA FMEIAERSLA VGEGAAGMER GLKDRYRRML MEKGVPEDHP VFRILYLDLT
     VCAMGLEHYL NRKNR
//