ID A0A2T6D2I3_9BACT Unreviewed; 1496 AA.
AC A0A2T6D2I3;
DT 18-JUL-2018, integrated into UniProtKB/TrEMBL.
DT 18-JUL-2018, sequence version 1.
DT 27-MAR-2024, entry version 20.
DE RecName: Full=histidine kinase {ECO:0000256|ARBA:ARBA00012438};
DE EC=2.7.13.3 {ECO:0000256|ARBA:ARBA00012438};
GN ORFNames=DB354_08255 {ECO:0000313|EMBL:PTX96640.1};
OS Opitutus sp. ER46.
OC Bacteria; Verrucomicrobiota; Opitutae; Opitutales; Opitutaceae; Opitutus.
OX NCBI_TaxID=2161864 {ECO:0000313|EMBL:PTX96640.1, ECO:0000313|Proteomes:UP000244023};
RN [1] {ECO:0000313|EMBL:PTX96640.1, ECO:0000313|Proteomes:UP000244023}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ER46 {ECO:0000313|EMBL:PTX96640.1,
RC ECO:0000313|Proteomes:UP000244023};
RA Buenger W., Mueller J., Hurek T., Reinhold-Hurek B.;
RT "Genomic and phenotypic characterization of four novel plant-associated
RT Verrucomicrobia indicate a new subdivision with one cultivated member.";
RL Submitted (MAR-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + protein L-histidine = ADP + protein N-phospho-L-
CC histidine.; EC=2.7.13.3; Evidence={ECO:0000256|ARBA:ARBA00000085};
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PTX96640.1}.
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DR EMBL; QAYX01000020; PTX96640.1; -; Genomic_DNA.
DR InParanoid; A0A2T6D2I3; -.
DR Proteomes; UP000244023; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0000155; F:phosphorelay sensor kinase activity; IEA:InterPro.
DR CDD; cd00082; HisKA; 1.
DR CDD; cd00130; PAS; 2.
DR Gene3D; 1.10.287.130; -; 1.
DR Gene3D; 2.10.70.100; -; 1.
DR Gene3D; 3.40.50.2300; -; 1.
DR Gene3D; 3.30.565.10; Histidine kinase-like ATPase, C-terminal domain; 1.
DR Gene3D; 2.60.40.10; Immunoglobulins; 1.
DR Gene3D; 3.30.450.20; PAS domain; 2.
DR Gene3D; 2.130.10.10; YVTN repeat-like/Quinoprotein amine dehydrogenase; 3.
DR InterPro; IPR011006; CheY-like_superfamily.
DR InterPro; IPR003594; HATPase_C.
DR InterPro; IPR036890; HATPase_C_sf.
DR InterPro; IPR005467; His_kinase_dom.
DR InterPro; IPR003661; HisK_dim/P.
DR InterPro; IPR036097; HisK_dim/P_sf.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR001610; PAC.
DR InterPro; IPR000014; PAS.
DR InterPro; IPR000700; PAS-assoc_C.
DR InterPro; IPR035965; PAS-like_dom_sf.
DR InterPro; IPR013655; PAS_fold_3.
DR InterPro; IPR011041; Quinoprot_gluc/sorb_DH.
DR InterPro; IPR004358; Sig_transdc_His_kin-like_C.
DR InterPro; IPR001789; Sig_transdc_resp-reg_receiver.
DR InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR NCBIfam; TIGR00229; sensory_box; 2.
DR PANTHER; PTHR43065:SF10; PEROXIDE STRESS-ACTIVATED HISTIDINE KINASE MAK3; 1.
DR PANTHER; PTHR43065; SENSOR HISTIDINE KINASE; 1.
DR Pfam; PF02518; HATPase_c; 1.
DR Pfam; PF00512; HisKA; 1.
DR Pfam; PF08447; PAS_3; 2.
DR Pfam; PF00072; Response_reg; 1.
DR PRINTS; PR00344; BCTRLSENSOR.
DR SMART; SM00387; HATPase_c; 1.
DR SMART; SM00388; HisKA; 1.
DR SMART; SM00086; PAC; 2.
DR SMART; SM00091; PAS; 2.
DR SMART; SM00448; REC; 1.
DR SUPFAM; SSF55874; ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase; 1.
DR SUPFAM; SSF63829; Calcium-dependent phosphotriesterase; 1.
DR SUPFAM; SSF52172; CheY-like; 1.
DR SUPFAM; SSF47384; Homodimeric domain of signal transducing histidine kinase; 1.
DR SUPFAM; SSF55785; PYP-like sensor domain (PAS domain); 2.
DR SUPFAM; SSF50952; Soluble quinoprotein glucose dehydrogenase; 1.
DR PROSITE; PS50109; HIS_KIN; 1.
DR PROSITE; PS50113; PAC; 2.
DR PROSITE; PS50112; PAS; 1.
DR PROSITE; PS50110; RESPONSE_REGULATORY; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553, ECO:0000256|PROSITE-
KW ProRule:PRU00169}; Reference proteome {ECO:0000313|Proteomes:UP000244023};
KW Signal {ECO:0000256|SAM:SignalP}; Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT SIGNAL 1..28
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 29..1496
FT /note="histidine kinase"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5015775015"
FT TRANSMEM 812..834
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 938..990
FT /note="PAC"
FT /evidence="ECO:0000259|PROSITE:PS50113"
FT DOMAIN 991..1058
FT /note="PAS"
FT /evidence="ECO:0000259|PROSITE:PS50112"
FT DOMAIN 1067..1119
FT /note="PAC"
FT /evidence="ECO:0000259|PROSITE:PS50113"
FT DOMAIN 1132..1355
FT /note="Histidine kinase"
FT /evidence="ECO:0000259|PROSITE:PS50109"
FT DOMAIN 1376..1493
FT /note="Response regulatory"
FT /evidence="ECO:0000259|PROSITE:PS50110"
FT MOD_RES 1427
FT /note="4-aspartylphosphate"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00169"
SQ SEQUENCE 1496 AA; 166494 MW; C688C8020FF7A8AD CRC64;
MWVKARWRNL MWILALFLRV LLTPSAIAAE PYQPLTVDPL SEPWRWRVFP QLAGMGVLCM
TEAADGTLWF GTADGLWHFD GVRWQADDGS TQLPGGVLAL HTTGDGRIFA AGRWGISEYR
DGTWSRRYEL AAERDTEVRR LVSLPDGTVW AASSYGAVEL RRTTCTLHTT AERAAQLRAA
HFNPAPAFSI QEWPAAVQEP ILPGNPPALA RHDLFEACRD AMGRLWFGTS GGELLRLTPA
ATPTSPPVWE LYNEKDGLVR GLRPYILGLK NGEVWVTYET RSAHLNQFDG TRWRATPLAT
LGLPEVCVNP LQTRDGAVWL SARYVVSAFR EGRWRTYERP AVPIPRARNI LCATRDGALW
IAGPNTEILR IDYSTHRWRT LDELMFQGED SAGREWFIHQ RGRIVCHDGD TWTSYGAEDG
GISVPVALIV TRAGDVWVAG SHENEAATAR FDGRRWTRTV HANFSWGIDG QAIWEGFDGA
LWFGAAVDTN GPARHRAGIL EYRDGRWIHH HQPGRVFPGE ADDDARTLLP ATQSPQPIGK
FSRIAGSPDG RVWAGRTILA AYDGKRWQRV SPAVGVSIDS VDTLFTSEER DLWLGTRRYG
AIRYDGRNWW RYQGSGSLEA NSVRDFAQTA DGTIWAATDR GYSRFDGQTW TSVLPGALTL
PDAGGSLRAG RENRIWINHY PPEWLRRGWP RVKPGAHAQA EAFRAYSHVP TGTPPDTVLR
PGPKVIGYPG HISVLWDGTA PWATGDDSRL EYSYRLDGGP WSAYTADRGT TLFSLGAGEH
LFEVRARDRS FNVDPTPAKL RLKVQPPVWR QAWFVVLLAA LVATAAVLLI RVLLERARLR
RTNRVLAEEI KSRERTEAAL RTSQAELKDA QHLSRLGTWH MSLATQQLEW SEEVVRTFEL
DASARGAPYD RVLARVHPDD RERVHRAFRR AIYDRLMFDI EFRVGVPDGR TKYVRAIGRI
LAGANGQSAS VSGSLQDITD RKESELQLRE SEERFRQLAE TITDAFWVAA TTPEPKVLYV
SPAFESIWGR RCSELIQDPG MWLASVHADD RERVSRTMAA RAAGVGYDEE YRILRPDGAV
SWVRDRAFPV QGAGGKVERM VGVARDVTSR RQMEAQLRQS QKMEAVGQLA GGVAHDFNNI
LSVIVMQVEL AHSDPALPTE LQECLQEIRA AALRAANLTR QLLLFSRRQE LQSRPVDLNE
VVGNLGKMLR RLIGEDIHLE IALHPSPLRT VADPGMLDQV VMNLVINSRD AMPAGGRLQI
TTAPREIDAQ AAARLRTVEP GSYVALTVTD SGAGIPPDVL PHVFEPFFTT KEAGKGTGLG
LATVFGIVKQ HRGGISVSSQ VGEGTRVEIF LPVITPTENA PDGNESSPAV SGGSETILLV
EDEPSMRLAV RGFLERHGYH VIEAESGARG RAQWEQNRGK IRLLLTDIVM PGRISGRQLA
RELRAEDPAL KVIYASGYAP EQKGEPLELE KADRFLPKPF APEQLLRLIR SLLDAR
//
