ID A0A2T6DR56_9BACT Unreviewed; 483 AA.
AC A0A2T6DR56;
DT 18-JUL-2018, integrated into UniProtKB/TrEMBL.
DT 18-JUL-2018, sequence version 1.
DT 27-MAR-2024, entry version 19.
DE RecName: Full=histidine kinase {ECO:0000256|ARBA:ARBA00012438};
DE EC=2.7.13.3 {ECO:0000256|ARBA:ARBA00012438};
GN ORFNames=DB347_19705 {ECO:0000313|EMBL:PTY04920.1};
OS Opitutaceae bacterium EW11.
OC Bacteria; Verrucomicrobiota; Opitutae; Opitutales; Opitutaceae.
OX NCBI_TaxID=2161865 {ECO:0000313|EMBL:PTY04920.1, ECO:0000313|Proteomes:UP000244239};
RN [1] {ECO:0000313|EMBL:PTY04920.1, ECO:0000313|Proteomes:UP000244239}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=EW11 {ECO:0000313|EMBL:PTY04920.1,
RC ECO:0000313|Proteomes:UP000244239};
RA Buenger W., Mueller J., Hurek T., Reinhold-Hurek B.;
RT "Genomic and phenotypic characterization of four novel plant-associated
RT Verrucomicrobia indicate a new subdivision with one cultivated member.";
RL Submitted (MAR-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + protein L-histidine = ADP + protein N-phospho-L-
CC histidine.; EC=2.7.13.3; Evidence={ECO:0000256|ARBA:ARBA00000085};
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PTY04920.1}.
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DR EMBL; QAYY01000013; PTY04920.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2T6DR56; -.
DR OrthoDB; 9796330at2; -.
DR Proteomes; UP000244239; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0000155; F:phosphorelay sensor kinase activity; IEA:InterPro.
DR CDD; cd06225; HAMP; 1.
DR CDD; cd00075; HATPase; 1.
DR CDD; cd00082; HisKA; 1.
DR Gene3D; 1.10.287.130; -; 1.
DR Gene3D; 6.10.340.10; -; 1.
DR Gene3D; 3.30.565.10; Histidine kinase-like ATPase, C-terminal domain; 1.
DR InterPro; IPR003660; HAMP_dom.
DR InterPro; IPR003594; HATPase_C.
DR InterPro; IPR036890; HATPase_C_sf.
DR InterPro; IPR005467; His_kinase_dom.
DR InterPro; IPR003661; HisK_dim/P.
DR InterPro; IPR036097; HisK_dim/P_sf.
DR InterPro; IPR004358; Sig_transdc_His_kin-like_C.
DR PANTHER; PTHR45436:SF5; SENSOR HISTIDINE KINASE TRCS; 1.
DR PANTHER; PTHR45436; SENSOR HISTIDINE KINASE YKOH; 1.
DR Pfam; PF00672; HAMP; 1.
DR Pfam; PF02518; HATPase_c; 1.
DR Pfam; PF00512; HisKA; 1.
DR PRINTS; PR00344; BCTRLSENSOR.
DR SMART; SM00304; HAMP; 1.
DR SMART; SM00387; HATPase_c; 1.
DR SMART; SM00388; HisKA; 1.
DR SUPFAM; SSF55874; ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase; 1.
DR SUPFAM; SSF158472; HAMP domain-like; 1.
DR SUPFAM; SSF47384; Homodimeric domain of signal transducing histidine kinase; 1.
DR PROSITE; PS50885; HAMP; 1.
DR PROSITE; PS50109; HIS_KIN; 1.
PE 4: Predicted;
KW Kinase {ECO:0000256|ARBA:ARBA00022777, ECO:0000313|EMBL:PTY04920.1};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW Reference proteome {ECO:0000313|Proteomes:UP000244239};
KW Transferase {ECO:0000256|ARBA:ARBA00022679};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius};
KW Two-component regulatory system {ECO:0000256|ARBA:ARBA00023012}.
FT TRANSMEM 14..36
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 175..198
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 199..252
FT /note="HAMP"
FT /evidence="ECO:0000259|PROSITE:PS50885"
FT DOMAIN 260..476
FT /note="Histidine kinase"
FT /evidence="ECO:0000259|PROSITE:PS50109"
SQ SEQUENCE 483 AA; 52709 MW; AD9563DF7684DF01 CRC64;
MRTFFHSIRW RVQAWHGAIL LTVILGFCLT SHRLAWNNQL RSVDRSLAQT ERTLIRGLMQ
AAEAHGEPGP GFSPRRLADK LRSNPEVFPS ALGAIFQGRE PGFAYFSLRD ADNRPLLQSP
NVPEDVAVPL HTPPEFAEEA RTVSGRREIV HRTPDGLVSI IGMDLGPERR EMRRFAWSLV
ALGGGVWLVG LLGGWWLAGR AIQPVADISR TASRIAEGNL EERIVPDGTN SELDQLSRVL
NATFDRLHAA LERQKQFTAD ASHELRTPVT ILLSETQRIL KRDRTPEEYR AVIQTCQATA
QRMRQLTEAL LLLARQDRGA GELRREPCDL AAILRTTAAQ LQPLADARGI QLRLELETAL
CMGDPTALSI LTTNLVGNAV EHHDRAGGVV VVGCGVHEGQ VRLAVSDDGP GIPAADLPHV
FDRFYRVDSA RSGGSGHVGL GLAIAKAIAT NHGGDIVAEN LPGRGCRFSV QLPARSPSAR
ASS
//
