ID   A0A2T6DV11_9BACT        Unreviewed;       448 AA.
AC   A0A2T6DV11;
DT   18-JUL-2018, integrated into UniProtKB/TrEMBL.
DT   18-JUL-2018, sequence version 1.
DT   24-JAN-2024, entry version 23.
DE   RecName: Full=Thymidylate synthase {ECO:0008006|Google:ProtNLM};
GN   ORFNames=DB347_12515 {ECO:0000313|EMBL:PTY06257.1};
OS   Opitutaceae bacterium EW11.
OC   Bacteria; Verrucomicrobiota; Opitutae; Opitutales; Opitutaceae.
OX   NCBI_TaxID=2161865 {ECO:0000313|EMBL:PTY06257.1, ECO:0000313|Proteomes:UP000244239};
RN   [1] {ECO:0000313|EMBL:PTY06257.1, ECO:0000313|Proteomes:UP000244239}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=EW11 {ECO:0000313|EMBL:PTY06257.1,
RC   ECO:0000313|Proteomes:UP000244239};
RA   Buenger W., Mueller J., Hurek T., Reinhold-Hurek B.;
RT   "Genomic and phenotypic characterization of four novel plant-associated
RT   Verrucomicrobia indicate a new subdivision with one cultivated member.";
RL   Submitted (MAR-2018) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:PTY06257.1}.
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DR   EMBL; QAYY01000010; PTY06257.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A2T6DV11; -.
DR   OrthoDB; 178972at2; -.
DR   Proteomes; UP000244239; Unassembled WGS sequence.
DR   GO; GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.
DR   GO; GO:0050797; F:thymidylate synthase (FAD) activity; IEA:UniProtKB-EC.
DR   GO; GO:0006231; P:dTMP biosynthetic process; IEA:InterPro.
DR   Gene3D; 3.30.1360.170; -; 1.
DR   InterPro; IPR003669; Thymidylate_synthase_ThyX.
DR   InterPro; IPR036098; Thymidylate_synthase_ThyX_sf.
DR   PANTHER; PTHR34934; FLAVIN-DEPENDENT THYMIDYLATE SYNTHASE; 1.
DR   PANTHER; PTHR34934:SF1; FLAVIN-DEPENDENT THYMIDYLATE SYNTHASE; 1.
DR   Pfam; PF02511; Thy1; 1.
DR   SUPFAM; SSF69796; Thymidylate synthase-complementing protein Thy1; 2.
DR   PROSITE; PS51331; THYX; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000244239}.
SQ   SEQUENCE   448 AA;  49515 MW;  E07AE4BB213CDF66 CRC64;
     MKVTGIATVP PPSAADLPKV TPELLASVLA RYSRSNEGLD SILAKVDLAN PDASIDRILK
     FVDYGHASIG GLTGGLAIAL DGVSMWLAYK IFEIAQMADG QESSTRYIAM DPANLPEPAI
     IGIPDDLAER WKDIMARAFA SYHSEYSRLD ALGAAQPELV RVPKDAKPAV VSRMRKNYAL
     DRARYFIPFA TRTNLAVVQS SRMWAQTVKQ LDSLPNAEAQ AAAKAIRDEL LKVSPRLMRH
     SSAEHSYQAQ AEQELNASLA LGLDRLSTKL VGDQAWVNVD RATPPFLSSV QSVSEALRHR
     SNRYGQQGTA TRRMRVTFAW NNLAIAELRD LNRHRTGHRY TPLIQAGFYL PPEIDRNAHA
     TLLADQAALT HELLKRGSPA YVYSLLLGAQ TPFEHSTQAD KFIYEAELRT GMGAHFRYAE
     HLSAVLREFF KQVPEAQAWV VEGTAEPE
//