ID A0A2T6DXG4_9BACT Unreviewed; 720 AA.
AC A0A2T6DXG4;
DT 18-JUL-2018, integrated into UniProtKB/TrEMBL.
DT 18-JUL-2018, sequence version 1.
DT 27-MAR-2024, entry version 21.
DE RecName: Full=histidine kinase {ECO:0000256|ARBA:ARBA00012438};
DE EC=2.7.13.3 {ECO:0000256|ARBA:ARBA00012438};
GN ORFNames=DB347_07400 {ECO:0000313|EMBL:PTY07129.1};
OS Opitutaceae bacterium EW11.
OC Bacteria; Verrucomicrobiota; Opitutae; Opitutales; Opitutaceae.
OX NCBI_TaxID=2161865 {ECO:0000313|EMBL:PTY07129.1, ECO:0000313|Proteomes:UP000244239};
RN [1] {ECO:0000313|EMBL:PTY07129.1, ECO:0000313|Proteomes:UP000244239}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=EW11 {ECO:0000313|EMBL:PTY07129.1,
RC ECO:0000313|Proteomes:UP000244239};
RA Buenger W., Mueller J., Hurek T., Reinhold-Hurek B.;
RT "Genomic and phenotypic characterization of four novel plant-associated
RT Verrucomicrobia indicate a new subdivision with one cultivated member.";
RL Submitted (MAR-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + protein L-histidine = ADP + protein N-phospho-L-
CC histidine.; EC=2.7.13.3; Evidence={ECO:0000256|ARBA:ARBA00000085};
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PTY07129.1}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; QAYY01000003; PTY07129.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2T6DXG4; -.
DR OrthoDB; 179990at2; -.
DR Proteomes; UP000244239; Unassembled WGS sequence.
DR GO; GO:0000155; F:phosphorelay sensor kinase activity; IEA:InterPro.
DR CDD; cd00082; HisKA; 1.
DR CDD; cd00130; PAS; 2.
DR Gene3D; 1.10.287.130; -; 1.
DR Gene3D; 2.10.70.100; -; 1.
DR Gene3D; 3.30.565.10; Histidine kinase-like ATPase, C-terminal domain; 1.
DR Gene3D; 3.30.450.20; PAS domain; 3.
DR InterPro; IPR003594; HATPase_C.
DR InterPro; IPR036890; HATPase_C_sf.
DR InterPro; IPR005467; His_kinase_dom.
DR InterPro; IPR003661; HisK_dim/P.
DR InterPro; IPR036097; HisK_dim/P_sf.
DR InterPro; IPR001610; PAC.
DR InterPro; IPR000014; PAS.
DR InterPro; IPR000700; PAS-assoc_C.
DR InterPro; IPR035965; PAS-like_dom_sf.
DR InterPro; IPR013656; PAS_4.
DR InterPro; IPR013655; PAS_fold_3.
DR InterPro; IPR004358; Sig_transdc_His_kin-like_C.
DR NCBIfam; TIGR00229; sensory_box; 2.
DR PANTHER; PTHR43304:SF1; PAC DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR43304; PHYTOCHROME-LIKE PROTEIN CPH1; 1.
DR Pfam; PF02518; HATPase_c; 1.
DR Pfam; PF00512; HisKA; 1.
DR Pfam; PF08447; PAS_3; 1.
DR Pfam; PF08448; PAS_4; 1.
DR PRINTS; PR00344; BCTRLSENSOR.
DR SMART; SM00387; HATPase_c; 1.
DR SMART; SM00388; HisKA; 1.
DR SMART; SM00086; PAC; 3.
DR SMART; SM00091; PAS; 3.
DR SUPFAM; SSF55874; ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase; 1.
DR SUPFAM; SSF47384; Homodimeric domain of signal transducing histidine kinase; 1.
DR SUPFAM; SSF55785; PYP-like sensor domain (PAS domain); 4.
DR PROSITE; PS50109; HIS_KIN; 1.
DR PROSITE; PS50113; PAC; 2.
DR PROSITE; PS50112; PAS; 2.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW Reference proteome {ECO:0000313|Proteomes:UP000244239}.
FT DOMAIN 44..115
FT /note="PAS"
FT /evidence="ECO:0000259|PROSITE:PS50112"
FT DOMAIN 117..169
FT /note="PAC"
FT /evidence="ECO:0000259|PROSITE:PS50113"
FT DOMAIN 330..401
FT /note="PAS"
FT /evidence="ECO:0000259|PROSITE:PS50112"
FT DOMAIN 405..458
FT /note="PAC"
FT /evidence="ECO:0000259|PROSITE:PS50113"
FT DOMAIN 501..715
FT /note="Histidine kinase"
FT /evidence="ECO:0000259|PROSITE:PS50109"
FT COILED 449..494
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 720 AA; 80881 MW; 37160025EBC64E7D CRC64;
MKKRSEPDAD HRTLREKIIG LGERSIRKSY YPQLQQQFEE VEKARVFLRT MFETTPDSIW
LLSADGTVLD ANSAAVAVME CASAEAAVGR SISSLVAPEF REGFRAFSAR VVAGQAGVLE
YAFVGLNGTR RWLETHAAPL QSHPGGPPMQ LAVTRDITQR KAADEALRQR EEQYRLIFEN
SPVSLWEEDF SAVKRFFDSL KSQGIEDLGR YFEQDPEAVR ACASRVRIVD VNRATLALVG
ASSKSEVLEG LPAMFTAESF AVFRKALECL WRGDTDMAAD TEIQTLSGQR RQVTLGFSVC
QGYEQTLSRV LVSLSDITER VEAAKRLHES EERLSLTLEA TQVGVWDWDV REDRFYASPT
YFTMLGYAPE THMLRSVWLE RVHPEDRAQV RQQIENLLSG VSETYGYEAR IRHADGSYRW
MQVSGLAMER DHAGRASRLL GIRVDITARK TAEETLRQMN QELDRRVREK TADLKEKSAA
LESMNGKLEA TNKELEAFVY SVSHDLRAPL RSIDGFSRAL LEDYHEKLDD EGRDNLQRIR
AGTARMGQLI DDMLALSRIQ LEPMRIANTG LSEIAEAVVG ELKRLEPGRS VEIVIAPNLA
AMCDARFLRV AFENLLGNAW KFTSRTPRAR IEVGVDAAGE TPVFYVRDNG AGFDMQYARR
LFGPFQRLHT TEEFPGTGIG LATVRRIVQR HGGRIWAESS VGNGATFYFT LGKTPDTAGE
//
