ID   A0A2T6E7B6_9GAMM        Unreviewed;       724 AA.
AC   A0A2T6E7B6;
DT   18-JUL-2018, integrated into UniProtKB/TrEMBL.
DT   18-JUL-2018, sequence version 1.
DT   27-MAR-2024, entry version 16.
DE   RecName: Full=Guanylate cyclase domain-containing protein {ECO:0000259|PROSITE:PS50125};
GN   ORFNames=BGP77_02570 {ECO:0000313|EMBL:PTY37277.1};
OS   Saccharospirillum sp. MSK14-1.
OC   Bacteria; Pseudomonadota; Gammaproteobacteria; Oceanospirillales;
OC   Saccharospirillaceae; Saccharospirillum.
OX   NCBI_TaxID=1897632 {ECO:0000313|EMBL:PTY37277.1, ECO:0000313|Proteomes:UP000244044};
RN   [1] {ECO:0000313|EMBL:PTY37277.1, ECO:0000313|Proteomes:UP000244044}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=MSK14-1 {ECO:0000313|EMBL:PTY37277.1,
RC   ECO:0000313|Proteomes:UP000244044};
RA   Nakajima Y., Yoshizawa S., Ogura Y., Hayashi T., Kogure K.;
RT   "Draft genome of Saccharospirillum sp. MSK14-1.";
RL   Submitted (AUG-2016) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:PTY37277.1}.
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DR   EMBL; MIES01000033; PTY37277.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A2T6E7B6; -.
DR   Proteomes; UP000244044; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   GO; GO:0004016; F:adenylate cyclase activity; IEA:UniProt.
DR   GO; GO:0009190; P:cyclic nucleotide biosynthetic process; IEA:InterPro.
DR   GO; GO:0035556; P:intracellular signal transduction; IEA:InterPro.
DR   CDD; cd07302; CHD; 1.
DR   Gene3D; 3.30.70.1230; Nucleotide cyclase; 1.
DR   InterPro; IPR001054; A/G_cyclase.
DR   InterPro; IPR007890; CHASE2.
DR   InterPro; IPR029787; Nucleotide_cyclase.
DR   PANTHER; PTHR43081; ADENYLATE CYCLASE, TERMINAL-DIFFERENTIATION SPECIFIC-RELATED; 1.
DR   PANTHER; PTHR43081:SF17; BLL5647 PROTEIN; 1.
DR   Pfam; PF05226; CHASE2; 1.
DR   Pfam; PF00211; Guanylate_cyc; 1.
DR   SMART; SM01080; CHASE2; 1.
DR   SMART; SM00044; CYCc; 1.
DR   SUPFAM; SSF55073; Nucleotide cyclase; 1.
DR   PROSITE; PS50125; GUANYLATE_CYCLASE_2; 1.
PE   4: Predicted;
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000244044};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        351..370
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        377..397
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          469..601
FT                   /note="Guanylate cyclase"
FT                   /evidence="ECO:0000259|PROSITE:PS50125"
SQ   SEQUENCE   724 AA;  80103 MW;  72B4FBFFC1423C11 CRC64;
     MITLSLAGYH LLVARYDQNS FIQRLDYLFY DWRFQLLDSG ERFARADDQI VIVDIDEASL
     KTEGRWPWPR DKLATLTHQL TEAGAVVIGF DILMSEPQLN PTRQLQQQAL ADGNTELADS
     LTPFIELTEY DQILADSFAN IDVVLPFLLQ ADASLRVGQL PAPVYQLSPQ QTERLLVVEA
     QGYAGAVDIL QNAAVTSGSI VPTIDGDGTL RSAPLVTRFE DGLYPSLSLA MGLTYYFLDG
     IELDIVPFNR QLDVIERLHF ADKSLRVDAG RVLVPYLGPQ GQFPYVSATD VINGRADTEV
     FTNALVLVGT SSVGLSDLRT TPVGTQFPGV EVHANLLNGL LAGNFPFTPD YGHTMTAVLL
     VILGVIFTLI SGRLGPLALA TATLLLLAIL VAINLSLWVY QQMALPLASS VLLTLALGTL
     HLLEGFLSER RHKQHVTHVF GQYVPKAHID RMLNEPEAYG FEGENRQMTV LFSDVRSFTT
     ISESLSATQL KDLLNRYFTP ITGVIFNHQG TIDKYVGDMV MAFWGAPLED PEHPRHALEA
     AVEMIDTTDA LNPELQALGY PEIQVGIGLN TGPMNVGDMG STYRRAYTVL GDAVNLGSRL
     ESLTKFYGVK ILIGPQTRAA IDDWAFRPID RIRVKGKTEP VAVFEPWGKL ADLTANQQAE
     LDALEHAQQL YLQQDWAAAR QAFEQLNAHS EHAKLYEVYL ERIAILEHET LPEDWDGSFT
     HTSK
//