ID   A0A2T6FJX1_9GAMM        Unreviewed;       290 AA.
AC   A0A2T6FJX1;
DT   18-JUL-2018, integrated into UniProtKB/TrEMBL.
DT   18-JUL-2018, sequence version 1.
DT   27-MAR-2024, entry version 12.
DE   RecName: Full=D-lactate dehydratase {ECO:0000256|ARBA:ARBA00013134};
DE            EC=4.2.1.130 {ECO:0000256|ARBA:ARBA00013134};
GN   ORFNames=B0W54_19230 {ECO:0000313|EMBL:PUA28738.1};
OS   Cellvibrio sp. 79.
OC   Bacteria; Pseudomonadota; Gammaproteobacteria; Cellvibrionales;
OC   Cellvibrionaceae; Cellvibrio.
OX   NCBI_TaxID=1954207 {ECO:0000313|EMBL:PUA28738.1, ECO:0000313|Proteomes:UP000243979};
RN   [1] {ECO:0000313|EMBL:PUA28738.1, ECO:0000313|Proteomes:UP000243979}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=79 {ECO:0000313|EMBL:PUA28738.1};
RA   Zhang Y., Xu J., Wang N.;
RT   "Cellvibrio sp. 79 recovered from metagenome.";
RL   Submitted (FEB-2017) to the EMBL/GenBank/DDBJ databases.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=H2O + methylglyoxal = (R)-lactate + H(+);
CC         Xref=Rhea:RHEA:27754, ChEBI:CHEBI:15377, ChEBI:CHEBI:15378,
CC         ChEBI:CHEBI:16004, ChEBI:CHEBI:17158; EC=4.2.1.130;
CC         Evidence={ECO:0000256|ARBA:ARBA00001524};
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:PUA28738.1}.
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DR   EMBL; MVDH01000003; PUA28738.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A2T6FJX1; -.
DR   Proteomes; UP000243979; Unassembled WGS sequence.
DR   CDD; cd03141; GATase1_Hsp31_like; 1.
DR   Gene3D; 3.40.50.880; -; 1.
DR   InterPro; IPR029062; Class_I_gatase-like.
DR   InterPro; IPR002818; DJ-1/PfpI.
DR   PANTHER; PTHR48094:SF11; GLUTATHIONE-INDEPENDENT GLYOXALASE HSP31-RELATED; 1.
DR   PANTHER; PTHR48094; PROTEIN/NUCLEIC ACID DEGLYCASE DJ-1-RELATED; 1.
DR   Pfam; PF01965; DJ-1_PfpI; 1.
DR   SUPFAM; SSF52317; Class I glutamine amidotransferase-like; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000243979};
KW   Signal {ECO:0000256|SAM:SignalP};
KW   Stress response {ECO:0000256|ARBA:ARBA00023016}.
FT   SIGNAL          1..25
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT   CHAIN           26..290
FT                   /note="D-lactate dehydratase"
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT                   /id="PRO_5015785511"
FT   DOMAIN          58..282
FT                   /note="DJ-1/PfpI"
FT                   /evidence="ECO:0000259|Pfam:PF01965"
SQ   SEQUENCE   290 AA;  30995 MW;  9365AF6B1FE9A32D CRC64;
     MKVRRLIATA LMVGVASATA VSVLAAENKG KVLVVVSSVS EIPLQDGKTY PTGYFLNELA
     VPVKALIAAG YEPVFANPKG NAANWDVHSL DAKFFAGDKQ ALEKMKSFAQ SLPGLKKPLS
     FAQVIKQGSA GYAGIFVPGG HAPLGDLTTN VELGKLLREF HNANKPTALI CHGPVALLSS
     LPDAQTFTTG MTTGDAAALE RASKNWIYAG YRLTVFGTAE ERMAEQSQLN GKVLFYPAEA
     LAEAGAIVES GKAWQNHVVK DRELITGRQP FSDEEFTSVF IKALDEQQAR
//