ID   A0A2T6ZBV1_TUBBO        Unreviewed;       407 AA.
AC   A0A2T6ZBV1;
DT   18-JUL-2018, integrated into UniProtKB/TrEMBL.
DT   18-JUL-2018, sequence version 1.
DT   08-NOV-2023, entry version 12.
DE   RecName: Full=NAD(P)-binding domain-containing protein {ECO:0000259|Pfam:PF16363};
GN   ORFNames=B9Z19DRAFT_1069399 {ECO:0000313|EMBL:PUU72894.1};
OS   Tuber borchii (White truffle).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Pezizomycetes;
OC   Pezizales; Tuberaceae; Tuber.
OX   NCBI_TaxID=42251 {ECO:0000313|EMBL:PUU72894.1, ECO:0000313|Proteomes:UP000244722};
RN   [1] {ECO:0000313|EMBL:PUU72894.1, ECO:0000313|Proteomes:UP000244722}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Tbo3840 {ECO:0000313|EMBL:PUU72894.1,
RC   ECO:0000313|Proteomes:UP000244722};
RG   DOE Joint Genome Institute;
RA   Murat C., Kuo A., Barry K.W., Clum A., Dockter R.B., Fauchery L., Iotti M.,
RA   Kohler A., Labutti K., Lindquist E.A., Lipzen A., Ohm R.A., Wang M.,
RA   Grigoriev I.V., Zambonelli A., Martin F.M.;
RT   "Draft genome sequence of Tuber borchii Vittad., a whitish edible
RT   truffle.";
RL   Submitted (APR-2017) to the EMBL/GenBank/DDBJ databases.
CC   -!- COFACTOR:
CC       Name=NAD(+); Xref=ChEBI:CHEBI:57540;
CC         Evidence={ECO:0000256|ARBA:ARBA00001911};
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:PUU72894.1}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; NESQ01000446; PUU72894.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A2T6ZBV1; -.
DR   STRING; 42251.A0A2T6ZBV1; -.
DR   Proteomes; UP000244722; Unassembled WGS sequence.
DR   GO; GO:0008460; F:dTDP-glucose 4,6-dehydratase activity; IEA:InterPro.
DR   GO; GO:0009225; P:nucleotide-sugar metabolic process; IEA:InterPro.
DR   CDD; cd05246; dTDP_GD_SDR_e; 1.
DR   Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR   Gene3D; 3.90.25.10; UDP-galactose 4-epimerase, domain 1; 1.
DR   InterPro; IPR005888; dTDP_Gluc_deHydtase.
DR   InterPro; IPR016040; NAD(P)-bd_dom.
DR   InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR   PANTHER; PTHR43000:SF7; DTDP-D-GLUCOSE 4,6-DEHYDRATASE; 1.
DR   PANTHER; PTHR43000; DTDP-D-GLUCOSE 4,6-DEHYDRATASE-RELATED; 1.
DR   Pfam; PF16363; GDP_Man_Dehyd; 1.
DR   SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
PE   4: Predicted;
KW   NAD {ECO:0000256|ARBA:ARBA00023027};
KW   Reference proteome {ECO:0000313|Proteomes:UP000244722}.
FT   DOMAIN          58..365
FT                   /note="NAD(P)-binding"
FT                   /evidence="ECO:0000259|Pfam:PF16363"
SQ   SEQUENCE   407 AA;  45502 MW;  EFDB9ACB60CFBB97 CRC64;
     MAPNRCELKL PGLLISFSDS AFSAVTHRHF QDTGIWRDAP VYKGATKFPP LEDAKNILIT
     GGAGFIACWL VRHLTLTYPE YNIISYDKLD YCASLNNTRC LSSAPNFTFV HGDITSPEEV
     QNAFRKYDID TVFHFAAQSH VDLSFGNSYE FTSTNVYGTH VLLECAKNHG SLKRFIHIST
     DEVYGEVDED GEDLIEQSIL APTNPYAASK AAAEMLVHSY YKSFKLPVII VRSNNVYGPH
     QFPEKVIPKF SCLLHRGEKL LLHGDGKHTR RYLFAGDAAD AFDTILHKGL IGQIYNVGST
     DEISNLELCA LLLKQFGHDP AVDFDSFVQH TIDRPFNDRR YAVDATKLKG LGWVQKTTFA
     EGLKTTVDWY RKFGGEWWGN IDLVLVPFPV VKDSEVVDAG NSGSKSS
//