ID   A0A2T7A1W0_TUBBO        Unreviewed;       746 AA.
AC   A0A2T7A1W0;
DT   18-JUL-2018, integrated into UniProtKB/TrEMBL.
DT   18-JUL-2018, sequence version 1.
DT   27-MAR-2024, entry version 18.
DE   RecName: Full=XPG-I domain-containing protein {ECO:0008006|Google:ProtNLM};
GN   ORFNames=B9Z19DRAFT_1062433 {ECO:0000313|EMBL:PUU81729.1};
OS   Tuber borchii (White truffle).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Pezizomycetes;
OC   Pezizales; Tuberaceae; Tuber.
OX   NCBI_TaxID=42251 {ECO:0000313|EMBL:PUU81729.1, ECO:0000313|Proteomes:UP000244722};
RN   [1] {ECO:0000313|EMBL:PUU81729.1, ECO:0000313|Proteomes:UP000244722}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Tbo3840 {ECO:0000313|EMBL:PUU81729.1,
RC   ECO:0000313|Proteomes:UP000244722};
RG   DOE Joint Genome Institute;
RA   Murat C., Kuo A., Barry K.W., Clum A., Dockter R.B., Fauchery L., Iotti M.,
RA   Kohler A., Labutti K., Lindquist E.A., Lipzen A., Ohm R.A., Wang M.,
RA   Grigoriev I.V., Zambonelli A., Martin F.M.;
RT   "Draft genome sequence of Tuber borchii Vittad., a whitish edible
RT   truffle.";
RL   Submitted (APR-2017) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:PUU81729.1}.
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DR   EMBL; NESQ01000041; PUU81729.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A2T7A1W0; -.
DR   STRING; 42251.A0A2T7A1W0; -.
DR   Proteomes; UP000244722; Unassembled WGS sequence.
DR   GO; GO:0008821; F:crossover junction DNA endonuclease activity; IEA:InterPro.
DR   GO; GO:0006281; P:DNA repair; IEA:UniProt.
DR   CDD; cd09906; H3TH_YEN1; 1.
DR   CDD; cd09870; PIN_YEN1; 1.
DR   Gene3D; 3.40.50.1010; 5'-nuclease; 2.
DR   InterPro; IPR036279; 5-3_exonuclease_C_sf.
DR   InterPro; IPR041177; GEN1_C.
DR   InterPro; IPR029060; PIN-like_dom_sf.
DR   InterPro; IPR006086; XPG-I_dom.
DR   InterPro; IPR006084; XPG/Rad2.
DR   InterPro; IPR006085; XPG_DNA_repair_N.
DR   InterPro; IPR037316; Yen1_H3TH.
DR   PANTHER; PTHR11081:SF71; ENDONUCLEASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_3G13260)-RELATED; 1.
DR   PANTHER; PTHR11081; FLAP ENDONUCLEASE FAMILY MEMBER; 1.
DR   Pfam; PF18380; GEN1_C; 1.
DR   Pfam; PF00867; XPG_I; 1.
DR   Pfam; PF00752; XPG_N; 1.
DR   PRINTS; PR00853; XPGRADSUPER.
DR   SMART; SM00484; XPGI; 1.
DR   SMART; SM00485; XPGN; 1.
DR   SUPFAM; SSF47807; 5' to 3' exonuclease, C-terminal subdomain; 1.
DR   SUPFAM; SSF88723; PIN domain-like; 1.
PE   4: Predicted;
KW   Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW   Nuclease {ECO:0000256|ARBA:ARBA00022722};
KW   Reference proteome {ECO:0000313|Proteomes:UP000244722}.
FT   DOMAIN          1..105
FT                   /note="XPG N-terminal"
FT                   /evidence="ECO:0000259|SMART:SM00485"
FT   DOMAIN          109..184
FT                   /note="XPG-I"
FT                   /evidence="ECO:0000259|SMART:SM00484"
FT   REGION          390..412
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          438..515
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          531..581
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          616..708
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        536..579
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        638..661
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   746 AA;  81927 MW;  AD2363CB412B6B09 CRC64;
     MGIVGLYQEL GPGPRVSLAK LSADHYISTG RRLRLAVDAS IWAFQVQAGK GGNNPALRTL
     YYRLIRLLHL NITPLFIFDG PNRPVFKRNH KTNTVMTPTL TRSTKALLKL FGFPYHEAPG
     EAEAECANLQ THGIVDAVLS EDVDTLMFGC EVTFRNWSGE GGKSKAPTHV SVYERESVEA
     MSGLTPEGMV LIALMRGGDY SPEGVPRCGI KIAADAARAG FGELLCALDV QDKEGLAAWR
     RRLQRELETN ESGYFKRKNK TIRIPEGFPD ITILGHYKKP VVSSKEKVER LRNSICWSGE
     INFSGLRESA RWAFEWRGKI GAAKFIRCLA PAVMSWNLCT STEGVRELVS GFHGRREHFS
     TGECRELRIS FVPGNVVKVD MDAEADDDVE VQPDDDEEFA QEGEDGSRKA RDYDPYTLER
     MWVLEVFARQ GVPEMVEEYE NPKPKAKKTA AATTKKSRLA RSKDKSVEAV HTMPEYLTVS
     KPGKQRPTPS KHPQEPRSSS SARRTQREVS VSLSSLTSHL SALQILEDDA FTHPAPSPTS
     VPTSKGNPCR QPLTSNPSTQ NHHPLPSERE TSQEQENIWT APAWPCETIG LSPPRGRGHP
     ALGAYGAAVS PQAVSPAVTA PAPEEERVTV SIPSSPEVET VRRRRVDQRR SSTDKKKNTS
     RGKTPVCILD ISDSESEGEV PDRRASPPLS LSGGRNEKKA VASGRANKKA VLRTSVEGSW
     KFADGEALAS GGGGWVDVEV MDLTGA
//