ID A0A2T7BKK6_9BACT Unreviewed; 359 AA.
AC A0A2T7BKK6;
DT 18-JUL-2018, integrated into UniProtKB/TrEMBL.
DT 18-JUL-2018, sequence version 1.
DT 24-JAN-2024, entry version 16.
DE RecName: Full=DNA topoisomerase {ECO:0000256|ARBA:ARBA00012891};
DE EC=5.6.2.1 {ECO:0000256|ARBA:ARBA00012891};
GN ORFNames=DCC81_01620 {ECO:0000313|EMBL:PUZ28207.1};
OS Chitinophaga parva.
OC Bacteria; Bacteroidota; Chitinophagia; Chitinophagales; Chitinophagaceae;
OC Chitinophaga.
OX NCBI_TaxID=2169414 {ECO:0000313|EMBL:PUZ28207.1, ECO:0000313|Proteomes:UP000244450};
RN [1] {ECO:0000313|EMBL:PUZ28207.1, ECO:0000313|Proteomes:UP000244450}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=LY-1 {ECO:0000313|EMBL:PUZ28207.1,
RC ECO:0000313|Proteomes:UP000244450};
RA Chen K.;
RT "Chitinophaga fuyangensis sp. nov., isolated from soil in a chemical
RT factory.";
RL Submitted (APR-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP-independent breakage of single-stranded DNA, followed by
CC passage and rejoining.; EC=5.6.2.1;
CC Evidence={ECO:0000256|ARBA:ARBA00000213};
CC -!- SIMILARITY: Belongs to the type IB topoisomerase family.
CC {ECO:0000256|ARBA:ARBA00006645}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PUZ28207.1}.
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DR EMBL; QCYK01000001; PUZ28207.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2T7BKK6; -.
DR OrthoDB; 9778962at2; -.
DR Proteomes; UP000244450; Unassembled WGS sequence.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0003917; F:DNA topoisomerase type I (single strand cut, ATP-independent) activity; IEA:InterPro.
DR GO; GO:0006265; P:DNA topological change; IEA:InterPro.
DR Gene3D; 1.10.132.120; -; 1.
DR Gene3D; 3.30.66.10; DNA topoisomerase I domain; 1.
DR InterPro; IPR011010; DNA_brk_join_enz.
DR InterPro; IPR035447; DNA_topo_I_N_sf.
DR InterPro; IPR049331; Top1B_N_bact.
DR InterPro; IPR001631; TopoI.
DR InterPro; IPR014711; TopoI_cat_a-hlx-sub_euk.
DR InterPro; IPR013500; TopoI_cat_euk.
DR Pfam; PF21338; Top1B_N_bact; 1.
DR Pfam; PF01028; Topoisom_I; 1.
DR PRINTS; PR00416; EUTPISMRASEI.
DR SUPFAM; SSF56349; DNA breaking-rejoining enzymes; 1.
DR SUPFAM; SSF55869; DNA topoisomerase I domain; 1.
PE 3: Inferred from homology;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Isomerase {ECO:0000256|ARBA:ARBA00023235, ECO:0000313|EMBL:PUZ28207.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000244450};
KW Topoisomerase {ECO:0000256|ARBA:ARBA00023029}.
FT DOMAIN 36..82
FT /note="DNA topoisomerase IB N-terminal"
FT /evidence="ECO:0000259|Pfam:PF21338"
FT DOMAIN 93..311
FT /note="DNA topoisomerase I catalytic core eukaryotic-type"
FT /evidence="ECO:0000259|Pfam:PF01028"
SQ SEQUENCE 359 AA; 41299 MW; A61F95E66931A706 CRC64;
MEVLQDPVAL AHAAKLRYVH ANKPGFTRVK ENGEMRYLDQ EGKEITDEET LHRIRGLVLP
PAWEQVWICP YANGHLQATG IDAAGRKQYR YHSRWAQVRN ETKYHRLLRF GEVLPRLRTQ
LKHNLRHRKL DKEKVIAIAL SVMEETMIRV GNSAYEKLYG SHGLTTLHNK HVIIQGSKAF
FHFKGKKGVE HKIELKHSTL ARLLQKVKEI PGQDLFQYYC EDGEHRCLDS GEVNDYLHQH
TGEDFTAKDF RTWAGTLHAM NLLADLAPFQ SAAECKRNVV GIIDGVAAKL GNTRAVSKKY
YIHPQILSSY ENGSLDPYLE LLRLQRDKPA RGALHNDEKI LLLFLKDLAR EKPRRRHAA
//
