ID   A0A2T7DGF6_9POAL        Unreviewed;       899 AA.
AC   A0A2T7DGF6;
DT   18-JUL-2018, integrated into UniProtKB/TrEMBL.
DT   18-JUL-2018, sequence version 1.
DT   27-MAR-2024, entry version 23.
DE   RecName: Full=PNPLA domain-containing protein {ECO:0000259|PROSITE:PS51635};
GN   ORFNames=GQ55_5G150000 {ECO:0000313|EMBL:PUZ54663.1};
OS   Panicum hallii var. hallii.
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; PACMAD clade;
OC   Panicoideae; Panicodae; Paniceae; Panicinae; Panicum;
OC   Panicum sect. Panicum.
OX   NCBI_TaxID=1504633 {ECO:0000313|EMBL:PUZ54663.1, ECO:0000313|Proteomes:UP000244336};
RN   [1] {ECO:0000313|EMBL:PUZ54663.1, ECO:0000313|Proteomes:UP000244336}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. HAL2 {ECO:0000313|Proteomes:UP000244336};
RA   Lovell J., Jenkins J., Lowry D., Mamidi S., Sreedasyam A., Weng X.,
RA   Barry K., Bonette J., Campitelli B., Daum C., Gordon S., Gould B.,
RA   Lipzen A., MacQueen A., Palacio-Mejia J., Plott C., Shakirov E., Shu S.,
RA   Yoshinaga Y., Zane M., Rokhsar D., Grimwood J., Schmutz J., Juenger T.;
RT   "WGS assembly of Panicum hallii var. hallii HAL2.";
RL   Submitted (APR-2018) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Possesses non-specific lipolytic acyl hydrolase (LAH)
CC       activity. Hydrolyzes phospholipids as well as galactolipids. May play a
CC       role in disease resistance. {ECO:0000256|ARBA:ARBA00025642}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; CM009753; PUZ54663.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A2T7DGF6; -.
DR   STRING; 1504633.A0A2T7DGF6; -.
DR   EnsemblPlants; PUZ54663; PUZ54663; GQ55_5G150000.
DR   Gramene; PUZ54663; PUZ54663; GQ55_5G150000.
DR   Proteomes; UP000244336; Chromosome 5.
DR   GO; GO:0004806; F:triglyceride lipase activity; IEA:InterPro.
DR   GO; GO:0016042; P:lipid catabolic process; IEA:UniProtKB-UniRule.
DR   CDD; cd07231; Pat_SDP1-like; 1.
DR   Gene3D; 3.40.1090.10; Cytosolic phospholipase A2 catalytic domain; 2.
DR   InterPro; IPR016035; Acyl_Trfase/lysoPLipase.
DR   InterPro; IPR002641; PNPLA_dom.
DR   InterPro; IPR021771; Triacylglycerol_lipase_N.
DR   PANTHER; PTHR14226; NEUROPATHY TARGET ESTERASE/SWISS CHEESE D.MELANOGASTER; 1.
DR   PANTHER; PTHR14226:SF10; TRIACYLGLYCEROL LIPASE 4-RELATED; 1.
DR   Pfam; PF11815; DUF3336; 1.
DR   Pfam; PF01734; Patatin; 1.
DR   SUPFAM; SSF52151; FabD/lysophospholipase-like; 1.
DR   PROSITE; PS51635; PNPLA; 1.
PE   4: Predicted;
KW   Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW   Lipid degradation {ECO:0000256|ARBA:ARBA00022963};
KW   Lipid metabolism {ECO:0000256|ARBA:ARBA00023098};
KW   Reference proteome {ECO:0000313|Proteomes:UP000244336}.
FT   DOMAIN          232..435
FT                   /note="PNPLA"
FT                   /evidence="ECO:0000259|PROSITE:PS51635"
FT   REGION          820..860
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          875..899
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        834..860
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   899 AA;  99931 MW;  5ABD63854C1A87E4 CRC64;
     MDDIASEAPV GAFAIGPSTA LGRAVALRVL LCGSAERLRH RLAAALRAAL HLAAAWLHPR
     DNTRGILLAV CAVALLLRGR RGRAGLRARV QSAYRRKFWR NMMRAALTYE EWAHAARMLE
     REAAPRRATD ADLYDEELVR NKLRELRHRR QEGSLRDIVF CMRADLLRNL GNMCNPELHK
     GRLQVPRLIK EYIEEVSTQL KMVCDSDSDE LPLEEKLAFM HETRHAFGRT ALLLSGGASL
     GSFHVGVVKT LVEHKLLPRI ISGSSVGSIM CSIVATRSWP ELESFFEEWH SLKFFDQMGG
     IFPVVKRILT HGAVHDIRHL QVLLRNLTSN LTFQEAYDMT GRILVVTVCS PRKHEPPRCL
     NYLTSPHVLI WSAVTASCAF PGLFEAQELM AKDRFGQTIP FHAPFLLGME ERNGATTRRW
     RDGSLESDLP IKQLKELFNV NHFIVSQANP HIAPLLRLKE IVRAYGGSFA AKLAELAEME
     VKHRCNQVLE LGFPLGGLAK LFAQDWEGDV TVVMPATLAQ YSKMIQNPSY AELQKAANQG
     RRCTWEKLSA IRANCAIELA LDECVALLNH LRRLKRSAER ASASQGHGPT IRLCPSRRIP
     SWNLIARENS TGSLEEEILT SPTRTNHQGP GGVAGLSNRN QYLQRIAHDS SDSESESIDL
     HSWTRSGGPL MRTASANKFI SFVQNLEIDT EFRTVPSRED EPELVTPNAS SLAAQAVSRE
     ANDRSLENSG LDFHDTTTRT AFGPSTSIMV SEGDLLQPEK IENGILFNVV RRDTLLGSSS
     GADSQGSPRE PDVETVQTEC LDCASASDDD DMELNVVNDA ATDPKRRNNL QHQESSLEEN
     VSRPSSLSCE DETNTNKPEA ASIFDICTEI HPATLSKENS QWEGSSENTE LEAAKDVMS
//